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The map label for this gene is yciR [C]

Identifier: 119943931

GI number: 119943931

Start: 187432

End: 189051

Strand: Direct

Name: yciR [C]

Synonym: Ping_0142

Alternate gene names: 119943931

Gene position: 187432-189051 (Clockwise)

Preceding gene: 119943929

Following gene: 119943932

Centisome position: 4.11

GC content: 39.32

Gene sequence:

>1620_bases
GTGGTGCACTTCTATGTTGAACAAGGGTTTACTCGCATTTCAGGCTACAGTGCAGAAGAGGTTATTGGACAGACACCCAA
GCTCTTTAGCTCAGGCCGACAAGACAAAGTGCTCTATAAGGCGATGTGGAACAGTATCAATACCACCGACGCATGGGAAG
GTGAAATCTGGAATCGCCGCAAAAACGGTGACACCTATTTAGCGCATATGACTATTGCCTCAGTGAGAGACACGGGCAAG
ATGATCTCTAATTATGTTGCTACGATCACCGATATTACCCTAAACAAAGCCGCCTCAGAAAAAATCAATAACCTCGCCTA
CTTTGATCAAATCACTCAGTTACCAAATCGTCTTTTGTTAGTTGATAGGCTTAATCTCGCCCTAGCTGAAAGTGCGCACA
GTAACCATCATGGTGCATTACTATTTATTGATTTAAACCAGCTTAAAATCATCAACAACACCCACGGGTACAGTGTGGGA
AATTTACTGTTAAAAGAAGTAACTGCTCGCTTAACTCAGATTGTAAGAAAAGCTGATACCATCGCCCGATTAAGCGGTGA
TGAGTTTGTAATACTTTTAGAAAAATTGAGTGAGCGAGACATTGAAGCTAACACCGAAATCCAAAATATTGCTAAAAAAA
TTATTTTTTTATTAACTCAACCTTACCAGCTCAATATGCACAAATATCGTGGCACCATCAGTATCGGCGCAACAATATTC
AATGGGAATGAATTTGCATCGGAAAAACTGTTAAAGCAAGCTGATATTGCTATGCATCAATCTAGGCTCGCAGGGCACAA
TCGCCTTTGTTTCTTTAATCAAACAATGCAAGAGGCTATTACAGCCCGTGCCGAGATGGAACATGAACTACGCGAAGCGA
TTGAACACAATCAATTTCAGCTATATTATCAAATACAGGTTAGCAGTTCTGGTCAAGCATTAGGGGCTGAAGCTTTAATC
CGTTGGCAACATCCAGAAGATGGTTATATTTCCCCCTTTAACTTTATCCCTTTAGCCGAAGAAACAGGACTTATTTTACC
AATAGGGGAATGGGTATTAAACACAGCCTGCGCTCAACTTAAAAAATGGCAAAAAAAACCACTGACACAAGATCTTGTAC
TCGCCGTTAATGTAAGTGCTCTACAAATTCATCAAGAAGACTTTGTAGAGCAACTAAAAAGCATCCTGCAAAAGCATGAA
ATCACCCCTGAACGACTTAAACTAGAACTAACTGAAAGTATGTTGGTAGAAAATGTCAGTGGCATTATTACCAAAATTAA
TACACTGAGAAAAATAGGTGTTTTATTCTCATTAGATGACTTTGGTACGGGTTATTCTTCTTTACAATATCTTAAAAAAT
TGCCCATCAATCAATTAAAAATAGACCAGTCATTTGTGCGTGACCTTCTCACGGATACCAATGACAGAGCGATTGTACGC
ACCATCATTACCATGTCACATAATTTAGGTATTAACGTTATTGCCGAGGGTGTAGAAACGGTAGAACAAAGACAATACTT
GTTGAGTGAAGGCTGTATGAATTATCAAGGCTATCTATTTAGTAAGCCCGTACCAATTGATGAGTTTGAAGCGTTGATTT
TTCGTTTAAGTGACACCTAA

Upstream 100 bases:

>100_bases
GTAATGAAACCAATTAAAAATTAACTTTCTTTCATGCAAGGATAGGTGTGAATATTTTTGTCCCATAATATGCCTCCAAA
TTAACTAAAGAATAGTTTAA

Downstream 100 bases:

>100_bases
TTTTAAACAGTGAGGGTTACCAATGTTACAGAAAGTCCAAACTCACTATTAAACAGCAATCACTATACGAAAGCGCAAGT
TTACTCAATTGCTTGAGCAT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MVHFYVEQGFTRISGYSAEEVIGQTPKLFSSGRQDKVLYKAMWNSINTTDAWEGEIWNRRKNGDTYLAHMTIASVRDTGK
MISNYVATITDITLNKAASEKINNLAYFDQITQLPNRLLLVDRLNLALAESAHSNHHGALLFIDLNQLKIINNTHGYSVG
NLLLKEVTARLTQIVRKADTIARLSGDEFVILLEKLSERDIEANTEIQNIAKKIIFLLTQPYQLNMHKYRGTISIGATIF
NGNEFASEKLLKQADIAMHQSRLAGHNRLCFFNQTMQEAITARAEMEHELREAIEHNQFQLYYQIQVSSSGQALGAEALI
RWQHPEDGYISPFNFIPLAEETGLILPIGEWVLNTACAQLKKWQKKPLTQDLVLAVNVSALQIHQEDFVEQLKSILQKHE
ITPERLKLELTESMLVENVSGIITKINTLRKIGVLFSLDDFGTGYSSLQYLKKLPINQLKIDQSFVRDLLTDTNDRAIVR
TIITMSHNLGINVIAEGVETVEQRQYLLSEGCMNYQGYLFSKPVPIDEFEALIFRLSDT

Sequences:

>Translated_539_residues
MVHFYVEQGFTRISGYSAEEVIGQTPKLFSSGRQDKVLYKAMWNSINTTDAWEGEIWNRRKNGDTYLAHMTIASVRDTGK
MISNYVATITDITLNKAASEKINNLAYFDQITQLPNRLLLVDRLNLALAESAHSNHHGALLFIDLNQLKIINNTHGYSVG
NLLLKEVTARLTQIVRKADTIARLSGDEFVILLEKLSERDIEANTEIQNIAKKIIFLLTQPYQLNMHKYRGTISIGATIF
NGNEFASEKLLKQADIAMHQSRLAGHNRLCFFNQTMQEAITARAEMEHELREAIEHNQFQLYYQIQVSSSGQALGAEALI
RWQHPEDGYISPFNFIPLAEETGLILPIGEWVLNTACAQLKKWQKKPLTQDLVLAVNVSALQIHQEDFVEQLKSILQKHE
ITPERLKLELTESMLVENVSGIITKINTLRKIGVLFSLDDFGTGYSSLQYLKKLPINQLKIDQSFVRDLLTDTNDRAIVR
TIITMSHNLGINVIAEGVETVEQRQYLLSEGCMNYQGYLFSKPVPIDEFEALIFRLSDT
>Mature_539_residues
MVHFYVEQGFTRISGYSAEEVIGQTPKLFSSGRQDKVLYKAMWNSINTTDAWEGEIWNRRKNGDTYLAHMTIASVRDTGK
MISNYVATITDITLNKAASEKINNLAYFDQITQLPNRLLLVDRLNLALAESAHSNHHGALLFIDLNQLKIINNTHGYSVG
NLLLKEVTARLTQIVRKADTIARLSGDEFVILLEKLSERDIEANTEIQNIAKKIIFLLTQPYQLNMHKYRGTISIGATIF
NGNEFASEKLLKQADIAMHQSRLAGHNRLCFFNQTMQEAITARAEMEHELREAIEHNQFQLYYQIQVSSSGQALGAEALI
RWQHPEDGYISPFNFIPLAEETGLILPIGEWVLNTACAQLKKWQKKPLTQDLVLAVNVSALQIHQEDFVEQLKSILQKHE
ITPERLKLELTESMLVENVSGIITKINTLRKIGVLFSLDDFGTGYSSLQYLKKLPINQLKIDQSFVRDLLTDTNDRAIVR
TIITMSHNLGINVIAEGVETVEQRQYLLSEGCMNYQGYLFSKPVPIDEFEALIFRLSDT

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=528, Percent_Identity=32.3863636363636, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI87081921, Length=494, Percent_Identity=33.4008097165992, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI226510982, Length=458, Percent_Identity=30.1310043668122, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1787055, Length=456, Percent_Identity=27.6315789473684, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=37.1900826446281, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=244, Percent_Identity=34.4262295081967, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081743, Length=244, Percent_Identity=35.655737704918, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=34.0336134453782, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788849, Length=452, Percent_Identity=28.7610619469027, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=32.6771653543307, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788502, Length=263, Percent_Identity=30.7984790874525, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87082096, Length=431, Percent_Identity=24.5939675174014, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788381, Length=297, Percent_Identity=26.5993265993266, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789650, Length=430, Percent_Identity=20.9302325581395, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=30.379746835443, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=28.1045751633987, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=31.3953488372093, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 61219; Mature: 61219

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHFYVEQGFTRISGYSAEEVIGQTPKLFSSGRQDKVLYKAMWNSINTTDAWEGEIWNRR
CEEEEEECCCHHHCCCCHHHHHCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
KNGDTYLAHMTIASVRDTGKMISNYVATITDITLNKAASEKINNLAYFDQITQLPNRLLL
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VDRLNLALAESAHSNHHGALLFIDLNQLKIINNTHGYSVGNLLLKEVTARLTQIVRKADT
HHHHHHHHHHCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
IARLSGDEFVILLEKLSERDIEANTEIQNIAKKIIFLLTQPYQLNMHKYRGTISIGATIF
HHHCCCCCEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHCCCEEEEEEEEE
NGNEFASEKLLKQADIAMHQSRLAGHNRLCFFNQTMQEAITARAEMEHELREAIEHNQFQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LYYQIQVSSSGQALGAEALIRWQHPEDGYISPFNFIPLAEETGLILPIGEWVLNTACAQL
EEEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCCEECCCCCCEEEEHHHHHHHHHHHHH
KKWQKKPLTQDLVLAVNVSALQIHQEDFVEQLKSILQKHEITPERLKLELTESMLVENVS
HHHHHCCCCCCEEEEEEHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GIITKINTLRKIGVLFSLDDFGTGYSSLQYLKKLPINQLKIDQSFVRDLLTDTNDRAIVR
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCEECCHHHHHHHHCCCCCHHHHH
TIITMSHNLGINVIAEGVETVEQRQYLLSEGCMNYQGYLFSKPVPIDEFEALIFRLSDT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHEECCC
>Mature Secondary Structure
MVHFYVEQGFTRISGYSAEEVIGQTPKLFSSGRQDKVLYKAMWNSINTTDAWEGEIWNRR
CEEEEEECCCHHHCCCCHHHHHCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
KNGDTYLAHMTIASVRDTGKMISNYVATITDITLNKAASEKINNLAYFDQITQLPNRLLL
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VDRLNLALAESAHSNHHGALLFIDLNQLKIINNTHGYSVGNLLLKEVTARLTQIVRKADT
HHHHHHHHHHCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
IARLSGDEFVILLEKLSERDIEANTEIQNIAKKIIFLLTQPYQLNMHKYRGTISIGATIF
HHHCCCCCEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHCCCEEEEEEEEE
NGNEFASEKLLKQADIAMHQSRLAGHNRLCFFNQTMQEAITARAEMEHELREAIEHNQFQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LYYQIQVSSSGQALGAEALIRWQHPEDGYISPFNFIPLAEETGLILPIGEWVLNTACAQL
EEEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCCEECCCCCCEEEEHHHHHHHHHHHHH
KKWQKKPLTQDLVLAVNVSALQIHQEDFVEQLKSILQKHEITPERLKLELTESMLVENVS
HHHHHCCCCCCEEEEEEHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GIITKINTLRKIGVLFSLDDFGTGYSSLQYLKKLPINQLKIDQSFVRDLLTDTNDRAIVR
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCEECCHHHHHHHHCCCCCHHHHH
TIITMSHNLGINVIAEGVETVEQRQYLLSEGCMNYQGYLFSKPVPIDEFEALIFRLSDT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]