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The map label for this gene is epsM [H]

Identifier: 119943899

GI number: 119943899

Start: 138640

End: 139122

Strand: Direct

Name: epsM [H]

Synonym: Ping_0106

Alternate gene names: 119943899

Gene position: 138640-139122 (Clockwise)

Preceding gene: 119943898

Following gene: 119943900

Centisome position: 3.04

GC content: 43.27

Gene sequence:

>483_bases
ATGGTCGAGCGCCTTAACACCTGGTGGGAAAGTATTACTGAAAGAGAGCAGCAACTATCATTAGTTTCTGTATTGCTGAT
ATTGATAGCCATTATTTACTGGGGCATATGGCAGCCGCTGTCTATCGGGCTTGATAATAGTGAAAATCAATTACAGCGAG
CCCAGCAGACCTTATCCACCACCCAACAGCGCGCAACTCTTTTAGTTAGCGCGGGTGTAGGACAAGGATCCGCTGTGAGT
GAAAACCAAAATGTTACCCAGATAGTCACCATCAGTGCGCAACAAAATGGTATTACTTTCTCCCGTATTATAAACCGCAA
TGAACAAGTTGAAGTGCAGGTAAGTAATGTTGAATTTGACCGTTTCATTAACTGGGTTTCCGTATTAAGCTCGCAATACT
CAGTGTCGGTTCTCAATGCGGATATATCTCGTGCAGATGAAGAAGGTTATATTAAAGTCACTCGCCTTTCCCTTGGGTAT
TAA

Upstream 100 bases:

>100_bases
AGTATTAGTGACGTACTAATAAGAAGGAAAAAATAATGGTCGAGTGGTTTAACTTTTGTTGGGAAAGTATTAGTGACGTA
CTAATAAGAAGGGAAAAATA

Downstream 100 bases:

>100_bases
ATCATGCCTTTAACTCTGCCAAAGAGATCCCATCTTCATGAAAATTAAGTTTATTATATTCTTTGTATCTTTTTATCTGG
TCGCGTTGCTTGCCACCTTA

Product: general secretion pathway M protein

Products: NA

Alternate protein names: Cholera toxin secretion protein epsM [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MVERLNTWWESITEREQQLSLVSVLLILIAIIYWGIWQPLSIGLDNSENQLQRAQQTLSTTQQRATLLVSAGVGQGSAVS
ENQNVTQIVTISAQQNGITFSRIINRNEQVEVQVSNVEFDRFINWVSVLSSQYSVSVLNADISRADEEGYIKVTRLSLGY

Sequences:

>Translated_160_residues
MVERLNTWWESITEREQQLSLVSVLLILIAIIYWGIWQPLSIGLDNSENQLQRAQQTLSTTQQRATLLVSAGVGQGSAVS
ENQNVTQIVTISAQQNGITFSRIINRNEQVEVQVSNVEFDRFINWVSVLSSQYSVSVLNADISRADEEGYIKVTRLSLGY
>Mature_160_residues
MVERLNTWWESITEREQQLSLVSVLLILIAIIYWGIWQPLSIGLDNSENQLQRAQQTLSTTQQRATLLVSAGVGQGSAVS
ENQNVTQIVTISAQQNGITFSRIINRNEQVEVQVSNVEFDRFINWVSVLSSQYSVSVLNADISRADEEGYIKVTRLSLGY

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3149

COG function: function code U; Type II secretory pathway, component PulM

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP M family [H]

Homologues:

Organism=Escherichia coli, GI1789339, Length=147, Percent_Identity=27.2108843537415, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007690
- InterPro:   IPR023229 [H]

Pfam domain/function: PF04612 GspM [H]

EC number: NA

Molecular weight: Translated: 18003; Mature: 18003

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERLNTWWESITEREQQLSLVSVLLILIAIIYWGIWQPLSIGLDNSENQLQRAQQTLST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHH
TQQRATLLVSAGVGQGSAVSENQNVTQIVTISAQQNGITFSRIINRNEQVEVQVSNVEFD
HHHHHEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCHH
RFINWVSVLSSQYSVSVLNADISRADEEGYIKVTRLSLGY
HHHHHHHHHHCCCEEEEEECHHHCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MVERLNTWWESITEREQQLSLVSVLLILIAIIYWGIWQPLSIGLDNSENQLQRAQQTLST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHH
TQQRATLLVSAGVGQGSAVSENQNVTQIVTISAQQNGITFSRIINRNEQVEVQVSNVEFD
HHHHHEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCHH
RFINWVSVLSSQYSVSVLNADISRADEEGYIKVTRLSLGY
HHHHHHHHHHCCCEEEEEECHHHCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8406031; 10952301 [H]