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The map label for this gene is can [H]

Identifier: 119900266

GI number: 119900266

Start: 4357121

End: 4357792

Strand: Direct

Name: can [H]

Synonym: azo3977

Alternate gene names: 119900266

Gene position: 4357121-4357792 (Clockwise)

Preceding gene: 119900265

Following gene: NA

Centisome position: 99.57

GC content: 63.69

Gene sequence:

>672_bases
ATGCAAACGACCCCGAATACCCCCGACATCCAGCTACTGTTCGACAACAACAAAGCCTGGTCCGAACGCATGCATGGTGA
AGATCCCGAGTACTTCACCCGGCTCGCCAACCAGCAAACACCCGAATACCTCTGGATCGGCTGCTCCGACAGCCGCGTTC
CCGCCAACCAGATCATCGGCCTCGCCCCGGGTGAGGTCTTCGTCCACCGCAACGTCGCCAACGTCGTGGTGCACACCGAC
CTCAACGCCCTCTCGGTGATCCAGTACGCCGTGGATGTGCTGCGCGTGAAACACATCCTGGTGGTCGGCCACTACGGCTG
CGGCGGGGTGAAGGCGGCGCTGAACAACAACCGCCTTGGCCTGATCGACAACTGGCTGCGTCATGTGCAGGACGTCCGCG
ACCTGCACGAAGCCACGCTGGCGCAGATCGAAGACCCCAACCTGCGGGTCGACCGGCTGTGCGAATTCAATGCCATGCAG
CAGGTCGTCAACATCTGCCAGACCTCGGTGCTGCGCGAAGCCTGGGCCCGTGGGCAGAAGGTGAATGTGCACGCCTGGTG
CTATGGCCTCAAGGACGGGCTGGTGCACGACCTCGGCATCGATGCGGGCAGCCGCGACGAGGCGCTCGAACAGTACCGCC
AGGCCGTCAGCCAGGTCCGCGACAGCGTCTGA

Upstream 100 bases:

>100_bases
TGCCGGCGCCTCGCGGCGCAAGCGCTTGACGGCGAATGTCCCGGCTGACAAGGCGGTCTCTATTATTCATAATTATGGAA
ACCCTGCCCGGCCCACACAG

Downstream 100 bases:

>100_bases
GCTGTCTTGCGACGGGCGTCGCGGCTGCCGCACGACGCCCGCCCACGTCCCGCCCCAGGCTCCACCCCCGTCAGGGACGC
GCGAGGCTCGCGCACGGCGC

Product: putative carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MQTTPNTPDIQLLFDNNKAWSERMHGEDPEYFTRLANQQTPEYLWIGCSDSRVPANQIIGLAPGEVFVHRNVANVVVHTD
LNALSVIQYAVDVLRVKHILVVGHYGCGGVKAALNNNRLGLIDNWLRHVQDVRDLHEATLAQIEDPNLRVDRLCEFNAMQ
QVVNICQTSVLREAWARGQKVNVHAWCYGLKDGLVHDLGIDAGSRDEALEQYRQAVSQVRDSV

Sequences:

>Translated_223_residues
MQTTPNTPDIQLLFDNNKAWSERMHGEDPEYFTRLANQQTPEYLWIGCSDSRVPANQIIGLAPGEVFVHRNVANVVVHTD
LNALSVIQYAVDVLRVKHILVVGHYGCGGVKAALNNNRLGLIDNWLRHVQDVRDLHEATLAQIEDPNLRVDRLCEFNAMQ
QVVNICQTSVLREAWARGQKVNVHAWCYGLKDGLVHDLGIDAGSRDEALEQYRQAVSQVRDSV
>Mature_223_residues
MQTTPNTPDIQLLFDNNKAWSERMHGEDPEYFTRLANQQTPEYLWIGCSDSRVPANQIIGLAPGEVFVHRNVANVVVHTD
LNALSVIQYAVDVLRVKHILVVGHYGCGGVKAALNNNRLGLIDNWLRHVQDVRDLHEATLAQIEDPNLRVDRLCEFNAMQ
QVVNICQTSVLREAWARGQKVNVHAWCYGLKDGLVHDLGIDAGSRDEALEQYRQAVSQVRDSV

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=52.8301886792453, Blast_Score=251, Evalue=2e-68,
Organism=Escherichia coli, GI1786534, Length=170, Percent_Identity=30, Blast_Score=83, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=201, Percent_Identity=29.3532338308458, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25116; Mature: 25116

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTPNTPDIQLLFDNNKAWSERMHGEDPEYFTRLANQQTPEYLWIGCSDSRVPANQIIG
CCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHEEE
LAPGEVFVHRNVANVVVHTDLNALSVIQYAVDVLRVKHILVVGHYGCGGVKAALNNNRLG
CCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEHHHCCCCCC
LIDNWLRHVQDVRDLHEATLAQIEDPNLRVDRLCEFNAMQQVVNICQTSVLREAWARGQK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VNVHAWCYGLKDGLVHDLGIDAGSRDEALEQYRQAVSQVRDSV
EEEEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTTPNTPDIQLLFDNNKAWSERMHGEDPEYFTRLANQQTPEYLWIGCSDSRVPANQIIG
CCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHEEE
LAPGEVFVHRNVANVVVHTDLNALSVIQYAVDVLRVKHILVVGHYGCGGVKAALNNNRLG
CCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEHHHCCCCCC
LIDNWLRHVQDVRDLHEATLAQIEDPNLRVDRLCEFNAMQQVVNICQTSVLREAWARGQK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VNVHAWCYGLKDGLVHDLGIDAGSRDEALEQYRQAVSQVRDSV
EEEEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]