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The map label for this gene is metX

Identifier: 119900260

GI number: 119900260

Start: 4351391

End: 4352518

Strand: Direct

Name: metX

Synonym: azo3971

Alternate gene names: 119900260

Gene position: 4351391-4352518 (Clockwise)

Preceding gene: 119900254

Following gene: 119900261

Centisome position: 99.44

GC content: 67.91

Gene sequence:

>1128_bases
ATGACCGAACCCCAATCCGTCGGCACCGTGGCGCCGCAGACGGCCCACTTCGACGAGCCCTTGCCGCTGCGCAGCGGCGG
CACGCTCGCCGGCTACGACCTGGTGTACGAAACCTATGGCCAGCTCAACGCGGCGCGCAGCAACGCCGTGCTGGTCTGCC
ACGCGCTGTCCGGCTCCCACCATGTGGCGGGCGTCTATGCGGACGACCCGCGCAACGTCGGCTGGTGGGACAACCTGGTC
GGCCCCGGCAAACCGCTCGATACGCGCAAGTTCTTCGTGATCGGGGTGAACAACCTCGGCGGCTGCTACGGCAGCACCGG
CCCCGGCTCGGTCAATCCGGCCACCGGGCGGCCGTGGGGCGCCGATTTCCCCTTCGTCACCGTCGAGGACTGGGTGGACG
CGCAGGCGCGACTCGCGGACCGCCTCGGCATCCAACGCTTCGCCGCGATCGTCGGCGGCAGCCTGGGCGGCATGCAGGCC
CTGTCCTGGACGCTGCAGTACCCGGAGCGCGTCGGCCACGCTGCCGTCATCGCCTCGGCGCCCAAGCTCACCGCGCAGAA
CATCGCCTTCAACGAGGTCGCGCGCCAGGCCATCCTGACCGACCCGGATTTTCACGGCGGCCATTATTACGAGCACGGCG
TGGTGCCGGCGCGCGGCCTGAAGCTGGCGCGCATGGTGGGCCACATAACCTATCTGTCGGACGACTCGATGGGTGAGAAA
TTCGGCCGCAGCCTGCGCCACGGCAAGGCGGTGTACAGCTACGACGTCGAGTTCGAGATCGAGTCCTACCTGCGCTACCA
GGGCGACAAGTTCGCCGGCTACTTCGACGCCAACACCTACCTGCTGACGACCAAGACGCTGGACTATTTCGATCCGGCCT
TCGAGCACGGCGGCAATCTCAACGCCGCGCTCGCCCGCGCCAGCGCCGACTTCCTGGTGGTGTCCTTCACCACCGACTGG
CGCTTCTCGCCGGCACGCTCGCGCGAGATCGTCTATGCGTTGCTGCACAACCGGCGCAACGTCAGCTACGCGGAGATCGA
CTGCCCCGCCGGGCACGACTCCTTCCTGCTCGACGACCCGCAATACCACGCGCTCCTCAGCGCCTGGTTCGACCGCATCG
AGGTGTAA

Upstream 100 bases:

>100_bases
GAACCACAGCTTGCGGGCGCTCAATAAATCCGGCTAAAGCGAGGGCGACCCAGTCCGCGTTTTCGAGCCGGCTGGGTTTT
TTGTTTTCCACGCACAGATC

Downstream 100 bases:

>100_bases
GGATGGCGGCCTATCGCTACGACTACGACGTGATCGCCCAGTGGATCGCCCCCGGCGAGAAGGTGCTGGACCTCGGCTGC
GGCGACGGCAGCCTGCTCAA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSHHVAGVYADDPRNVGWWDNLV
GPGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWGADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQA
LSWTLQYPERVGHAAVIASAPKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEK
FGRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNLNAALARASADFLVVSFTTDW
RFSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDPQYHALLSAWFDRIEV

Sequences:

>Translated_375_residues
MTEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSHHVAGVYADDPRNVGWWDNLV
GPGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWGADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQA
LSWTLQYPERVGHAAVIASAPKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEK
FGRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNLNAALARASADFLVVSFTTDW
RFSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDPQYHALLSAWFDRIEV
>Mature_374_residues
TEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSHHVAGVYADDPRNVGWWDNLVG
PGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWGADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQAL
SWTLQYPERVGHAAVIASAPKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEKF
GRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNLNAALARASADFLVVSFTTDWR
FSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDPQYHALLSAWFDRIEV

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=37.0535714285714, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_AZOSB (A1KCN1)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_935473.1
- STRING:   A1KCN1
- GeneID:   4609939
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3971
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   A1KCN1
- ProtClustDB:   PRK00175
- BioCyc:   ASP62928:AZO3971-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41115; Mature: 40984

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: ACT_SITE 154-154 ACT_SITE 352-352

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
HVAGVYADDPRNVGWWDNLVGPGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWG
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
ADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQALSWTLQYPERVGHAAVIASA
CCCCEEEHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHHCCCEEEEECC
PKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEK
CCCCHHCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHEEEECCCHHHHH
FGRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNL
HHHHHHCCCEEEEEEEEEEHHHHHHHCCCCEEEEECCCEEEEEECCCHHCCHHHHCCCCC
NAALARASADFLVVSFTTDWRFSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDP
CHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCH
QYHALLSAWFDRIEV
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEPQSVGTVAPQTAHFDEPLPLRSGGTLAGYDLVYETYGQLNAARSNAVLVCHALSGSH
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
HVAGVYADDPRNVGWWDNLVGPGKPLDTRKFFVIGVNNLGGCYGSTGPGSVNPATGRPWG
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
ADFPFVTVEDWVDAQARLADRLGIQRFAAIVGGSLGGMQALSWTLQYPERVGHAAVIASA
CCCCEEEHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHHCCCEEEEECC
PKLTAQNIAFNEVARQAILTDPDFHGGHYYEHGVVPARGLKLARMVGHITYLSDDSMGEK
CCCCHHCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHEEEECCCHHHHH
FGRSLRHGKAVYSYDVEFEIESYLRYQGDKFAGYFDANTYLLTTKTLDYFDPAFEHGGNL
HHHHHHCCCEEEEEEEEEEHHHHHHHCCCCEEEEECCCEEEEEECCCHHCCHHHHCCCCC
NAALARASADFLVVSFTTDWRFSPARSREIVYALLHNRRNVSYAEIDCPAGHDSFLLDDP
CHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCH
QYHALLSAWFDRIEV
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA