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The map label for this gene is sciK [H]

Identifier: 119900187

GI number: 119900187

Start: 4275831

End: 4276337

Strand: Direct

Name: sciK [H]

Synonym: azo3898

Alternate gene names: 119900187

Gene position: 4275831-4276337 (Clockwise)

Preceding gene: 119900186

Following gene: 119900188

Centisome position: 97.71

GC content: 67.06

Gene sequence:

>507_bases
ATGGCCTCCGGCGACATGTTCCTCAAAATCGAAGGCGCGCGCATGGGCCCCATCAAGGGCGAGGCCCAGGACGCCCTGCA
CAAGGACGAGATCGACATCCTGTCCTGGAGCTGGGGCATGCAGGGCAATGCCAGCGCCACCGCCACCGCGGGCGGCCGCA
GCGGCGGCGCCAGCCAGGTTTCGGTCAGCGAACTGGTCGTCTCCAAGGGTTTCGACCGCGCCAGCACCGCACTGCTGGTC
GCGCTGCGCTCCAACGAACAGATCAAGCGCGCCGTCCTCACGATGCGCAAGGCCGGTGGCCCGAAGGCGGTCGAGTTCCT
CGTCATCACGATGGAAAACGCCCGCATCCGCTCGGTCCAGCTGTCCGGCGCCGGCACCGGCGATGACCCGGTGCACGAGC
AGGTCTCCATCTCGTTCCAGAAAATCGCCGTCGAATACCGCGGCCAGGAAGGCAGCGGCGGCGGCAACGCCGTATCGCGC
TTCGAAACCGACGTCACGCCCCAATAA

Upstream 100 bases:

>100_bases
AGGCGGCTTCCTGCGATCGCCGCGGACGCCCACCGGTGGATCCGTGCCTGCGACCGCTTTGTTCCCCGGCAGTTAAACCG
CCCCGCGACAGGAATTCCTC

Downstream 100 bases:

>100_bases
GCCGAGGAGAGGACCATGTCCGCCCCCGCCAAAACCCTAGCCGACGCCGAAGCCGCGCTGCGCGCCGGCGACCCCGACGC
CGCCCTCGCCCAGCTGCAGG

Product: putative cytoplasmic protein SciK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MASGDMFLKIEGARMGPIKGEAQDALHKDEIDILSWSWGMQGNASATATAGGRSGGASQVSVSELVVSKGFDRASTALLV
ALRSNEQIKRAVLTMRKAGGPKAVEFLVITMENARIRSVQLSGAGTGDDPVHEQVSISFQKIAVEYRGQEGSGGGNAVSR
FETDVTPQ

Sequences:

>Translated_168_residues
MASGDMFLKIEGARMGPIKGEAQDALHKDEIDILSWSWGMQGNASATATAGGRSGGASQVSVSELVVSKGFDRASTALLV
ALRSNEQIKRAVLTMRKAGGPKAVEFLVITMENARIRSVQLSGAGTGDDPVHEQVSISFQKIAVEYRGQEGSGGGNAVSR
FETDVTPQ
>Mature_167_residues
ASGDMFLKIEGARMGPIKGEAQDALHKDEIDILSWSWGMQGNASATATAGGRSGGASQVSVSELVVSKGFDRASTALLVA
LRSNEQIKRAVLTMRKAGGPKAVEFLVITMENARIRSVQLSGAGTGDDPVHEQVSISFQKIAVEYRGQEGSGGGNAVSRF
ETDVTPQ

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 17653; Mature: 17522

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGDMFLKIEGARMGPIKGEAQDALHKDEIDILSWSWGMQGNASATATAGGRSGGASQV
CCCCCEEEEECCCEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCH
SVSELVVSKGFDRASTALLVALRSNEQIKRAVLTMRKAGGPKAVEFLVITMENARIRSVQ
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEE
LSGAGTGDDPVHEQVSISFQKIAVEYRGQEGSGGGNAVSRFETDVTPQ
ECCCCCCCCCCCHHHEEEEEEEEEEECCCCCCCCCCCHHEECCCCCCC
>Mature Secondary Structure 
ASGDMFLKIEGARMGPIKGEAQDALHKDEIDILSWSWGMQGNASATATAGGRSGGASQV
CCCCEEEEECCCEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCH
SVSELVVSKGFDRASTALLVALRSNEQIKRAVLTMRKAGGPKAVEFLVITMENARIRSVQ
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEE
LSGAGTGDDPVHEQVSISFQKIAVEYRGQEGSGGGNAVSRFETDVTPQ
ECCCCCCCCCCCHHHEEEEEEEEEEECCCCCCCCCCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]