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The map label for this gene is cobU [H]

Identifier: 119899846

GI number: 119899846

Start: 3903450

End: 3904043

Strand: Direct

Name: cobU [H]

Synonym: azo3557

Alternate gene names: 119899846

Gene position: 3903450-3904043 (Clockwise)

Preceding gene: 119899837

Following gene: 119899849

Centisome position: 89.2

GC content: 74.58

Gene sequence:

>594_bases
ATGATACCGTGTCCGGCTCTTTCCGTAACGAGAAACATCGACCCCGCCATGAGCTGCGAACTGATCCTGGGCGGCGCCCG
CTCGGGCAAGAGCCGCCACGCCGAAGCGCTCGCCGGCGCCAGCGGCCTCGCCGTCACCGTGATCGCCACCGCCGAGGGCG
GCGACGCCGAGATGAGCGCGCGCATCCGCCGCCACCAGGCGGACCGCCCCGCGCACTGGCGCACCGTGGAAGAACCGCTG
GCGCTCGCCGCGGCGCTGCGGCGCGAGGCCGACGCTGGGCGCTGCGTGATCGTCGATTGCCTGACGCTGTGGCTGACCAA
CCTGCTGGCGGGCGCCGAAACCCTGCCGCCCGAAGCGGGCGCGGACGCCCTGCCGCGCTTTCGCGCCGAGCGCGACGCCC
TGCTCGACGTGCTGCCCGCGCTGCCGGGCGAGATCCTGCTGGTGGCCAACGAGGTGGGGCTGGGCCTGGTGCCGGAAACG
CCGCTCGGGCGCCTGTTCCGCGACGAGGCGGGCCGGCTCAATCAGGCGATCGCGGCGCGCGTGCCGCGGGTCAGCTTCGT
CGCCGCGGGCCTGCCGCTGCGGCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
ATTGCGCCGGAGGCGCGCACCTGTTTCCCGTTTAACCCTGGGGCGAGGACCGCCTTCGGGCACCTGAAACGCGCCGCACC
TTTCGGCGCGGAGCGCCCGG

Downstream 100 bases:

>100_bases
TCAGCGCAGCCCGAGCGCGCGCAGCCGCTCTTCGGTGGCGGGGTGGGTGGAGAGGTAGTCCTGCCAGCCGGATTCCGACG
CGGCGCAGTCGGCCTCGGGC

Product: cobinamide kinase/cobinamide phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIPCPALSVTRNIDPAMSCELILGGARSGKSRHAEALAGASGLAVTVIATAEGGDAEMSARIRRHQADRPAHWRTVEEPL
ALAAALRREADAGRCVIVDCLTLWLTNLLAGAETLPPEAGADALPRFRAERDALLDVLPALPGEILLVANEVGLGLVPET
PLGRLFRDEAGRLNQAIAARVPRVSFVAAGLPLRLKG

Sequences:

>Translated_197_residues
MIPCPALSVTRNIDPAMSCELILGGARSGKSRHAEALAGASGLAVTVIATAEGGDAEMSARIRRHQADRPAHWRTVEEPL
ALAAALRREADAGRCVIVDCLTLWLTNLLAGAETLPPEAGADALPRFRAERDALLDVLPALPGEILLVANEVGLGLVPET
PLGRLFRDEAGRLNQAIAARVPRVSFVAAGLPLRLKG
>Mature_197_residues
MIPCPALSVTRNIDPAMSCELILGGARSGKSRHAEALAGASGLAVTVIATAEGGDAEMSARIRRHQADRPAHWRTVEEPL
ALAAALRREADAGRCVIVDCLTLWLTNLLAGAETLPPEAGADALPRFRAERDALLDVLPALPGEILLVANEVGLGLVPET
PLGRLFRDEAGRLNQAIAARVPRVSFVAAGLPLRLKG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=179, Percent_Identity=43.5754189944134, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20697; Mature: 20697

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPCPALSVTRNIDPAMSCELILGGARSGKSRHAEALAGASGLAVTVIATAEGGDAEMSA
CCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
RIRRHQADRPAHWRTVEEPLALAAALRREADAGRCVIVDCLTLWLTNLLAGAETLPPEAG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ADALPRFRAERDALLDVLPALPGEILLVANEVGLGLVPETPLGRLFRDEAGRLNQAIAAR
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VPRVSFVAAGLPLRLKG
CCCCEEEECCCCEEECC
>Mature Secondary Structure
MIPCPALSVTRNIDPAMSCELILGGARSGKSRHAEALAGASGLAVTVIATAEGGDAEMSA
CCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
RIRRHQADRPAHWRTVEEPLALAAALRREADAGRCVIVDCLTLWLTNLLAGAETLPPEAG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ADALPRFRAERDALLDVLPALPGEILLVANEVGLGLVPETPLGRLFRDEAGRLNQAIAAR
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VPRVSFVAAGLPLRLKG
CCCCEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]