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The map label for this gene is modD [H]

Identifier: 119899654

GI number: 119899654

Start: 3701590

End: 3702435

Strand: Reverse

Name: modD [H]

Synonym: azo3365

Alternate gene names: 119899654

Gene position: 3702435-3701590 (Counterclockwise)

Preceding gene: 119899655

Following gene: 119899652

Centisome position: 84.61

GC content: 71.39

Gene sequence:

>846_bases
ATGCCACGCTCCGTCCTAGCCGATCACGAACTGGCCGCGTTGCTGGCCGACGACGTGCCCTGCGGCGATCTCACCACCGA
CGCGCTGCGCATCGGCCCGCAGCCGGCGCGGCTGAGCTTCATCGCGCGCCAGCCGATGACCGTGTGCGGGGTCGAGGAAG
CCGTGCGGATGTTCGAACTCGCCGGCGCCGCGGTGAAGGCCGAACTCGCCTCCGGCGACGTGCTCAGCTTCCAGTCGCCC
ATCCTGACCGCCGAAGGCGATGCCGACGTGCTGCACCGGGTATGGAAGACCGCCCAGGTGCTGGTCGAGTGGGCGAGCGG
CATCGCCAGCAGCGCTTCCGCCATCGTCGAGGCCGCCCAGCACGACGGCCGCCGCGTGCCGGTGGCCTGCACCCGCAAGA
CCGTGCCGGGCACCAAGGCGCTGTCGGTCAAGGCGGTGCGCTGCGCTGGCGCCAGCATGCACCGCTTGGGCCTTTCGGAG
ACCCTGCTGGTGTTCCCCGAGCACCGGCTCTACCTGGATGAGGCCCCGGCGGTCACCATCGCCCGCCTGCGCGCGGCCGA
AGCGGAAAAGCGCATCGTCGTCGAGGTGGGCTCGGTGGAGGAGGCGGTGGTGTGGACCGAGGCCGGCGCCGACGTGATCC
AGCTGGAGAAATTTCCGCCCGAACGGGTGGCCGAGTGCCGCGCCGCGATCGCCCACAGCCGGATGCGCCCCTTGCTGGCG
GCCGCCGGCGGCATCAAGGCGGACAACGCCGGCGCCTACGTGGCGGCGGGGGCCGATGTGCTGGTGACGTCGGCGCCATT
TACTGCGGCGCCGCGGGATGTGAAGGTGACGTTCTTGCGGGATTGA

Upstream 100 bases:

>100_bases
TCGCGTCACTGATCACCGGCGCCGCCGTGCTCCGCGCGCGGCGGCCTCCGTTTTTCCGCGCCGGCTGCCTCCGGGCGGCC
GGTTCCACAGGGGAAGCCGC

Downstream 100 bases:

>100_bases
TTACGGCGAAACGCGCTTTTTTCGGCGGCGAGGCGATGAGCGCCTCGCTCCCTCTCCTTCAAGGGGTGAGGACGGGGTTT
CGCCTAGCATTGCTTGCCGT

Product: putative molybdenum transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPRSVLADHELAALLADDVPCGDLTTDALRIGPQPARLSFIARQPMTVCGVEEAVRMFELAGAAVKAELASGDVLSFQSP
ILTAEGDADVLHRVWKTAQVLVEWASGIASSASAIVEAAQHDGRRVPVACTRKTVPGTKALSVKAVRCAGASMHRLGLSE
TLLVFPEHRLYLDEAPAVTIARLRAAEAEKRIVVEVGSVEEAVVWTEAGADVIQLEKFPPERVAECRAAIAHSRMRPLLA
AAGGIKADNAGAYVAAGADVLVTSAPFTAAPRDVKVTFLRD

Sequences:

>Translated_281_residues
MPRSVLADHELAALLADDVPCGDLTTDALRIGPQPARLSFIARQPMTVCGVEEAVRMFELAGAAVKAELASGDVLSFQSP
ILTAEGDADVLHRVWKTAQVLVEWASGIASSASAIVEAAQHDGRRVPVACTRKTVPGTKALSVKAVRCAGASMHRLGLSE
TLLVFPEHRLYLDEAPAVTIARLRAAEAEKRIVVEVGSVEEAVVWTEAGADVIQLEKFPPERVAECRAAIAHSRMRPLLA
AAGGIKADNAGAYVAAGADVLVTSAPFTAAPRDVKVTFLRD
>Mature_280_residues
PRSVLADHELAALLADDVPCGDLTTDALRIGPQPARLSFIARQPMTVCGVEEAVRMFELAGAAVKAELASGDVLSFQSPI
LTAEGDADVLHRVWKTAQVLVEWASGIASSASAIVEAAQHDGRRVPVACTRKTVPGTKALSVKAVRCAGASMHRLGLSET
LLVFPEHRLYLDEAPAVTIARLRAAEAEKRIVVEVGSVEEAVVWTEAGADVIQLEKFPPERVAECRAAIAHSRMRPLLAA
AGGIKADNAGAYVAAGADVLVTSAPFTAAPRDVKVTFLRD

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=251, Percent_Identity=29.4820717131474, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786299, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321162, Length=273, Percent_Identity=27.4725274725275, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 29643; Mature: 29512

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSVLADHELAALLADDVPCGDLTTDALRIGPQPARLSFIARQPMTVCGVEEAVRMFEL
CCCCHHCCHHHHHHHHCCCCCCCCCCHHHHCCCCCHHEEEECCCCCCEECHHHHHHHHHH
AGAAVKAELASGDVLSFQSPILTAEGDADVLHRVWKTAQVLVEWASGIASSASAIVEAAQ
HCHHHEEECCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDGRRVPVACTRKTVPGTKALSVKAVRCAGASMHRLGLSETLLVFPEHRLYLDEAPAVTI
HCCCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCEEEECCCCCHHH
ARLRAAEAEKRIVVEVGSVEEAVVWTEAGADVIQLEKFPPERVAECRAAIAHSRMRPLLA
HHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
AAGGIKADNAGAYVAAGADVLVTSAPFTAAPRDVKVTFLRD
HCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
PRSVLADHELAALLADDVPCGDLTTDALRIGPQPARLSFIARQPMTVCGVEEAVRMFEL
CCCHHCCHHHHHHHHCCCCCCCCCCHHHHCCCCCHHEEEECCCCCCEECHHHHHHHHHH
AGAAVKAELASGDVLSFQSPILTAEGDADVLHRVWKTAQVLVEWASGIASSASAIVEAAQ
HCHHHEEECCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDGRRVPVACTRKTVPGTKALSVKAVRCAGASMHRLGLSETLLVFPEHRLYLDEAPAVTI
HCCCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCEEEECCCCCHHH
ARLRAAEAEKRIVVEVGSVEEAVVWTEAGADVIQLEKFPPERVAECRAAIAHSRMRPLLA
HHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
AAGGIKADNAGAYVAAGADVLVTSAPFTAAPRDVKVTFLRD
HCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]