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The map label for this gene is 119899577

Identifier: 119899577

GI number: 119899577

Start: 3626917

End: 3627633

Strand: Direct

Name: 119899577

Synonym: azo3288

Alternate gene names: NA

Gene position: 3626917-3627633 (Clockwise)

Preceding gene: 119899576

Following gene: 119899578

Centisome position: 82.88

GC content: 67.64

Gene sequence:

>717_bases
ATGCGCTCTGAAATCATCCACCACGGTGGCCGCGACGGCGTAACCGGCTCCTGCCACCAGCTGCTGTTTGGCAACGGCGA
CAGCATCCTTATCGATTGCGGCCTGTTCCAGGGCGCCGAAACCGCCGCCGACGGTCGCGGCGCTGAGGATGCCCTTGCGT
TTCGCATGCCGGTTTCAGCGATACGGGCACTCGTCGTCAGCCATGTCCACATCGACCACGTCGGGCGCATCCCCTGGCTG
CTCGCTGCGGGATTCAAGGGGCCGATCATCTGCAGCGAGCCGTCCGCACGGCTGCTGCCGACGGTCCTCGCAGACGCCTT
CGCGCTCGGCATCGCACGCGATCCCCAACTGGTGCAACGCTACATCGACATGGTGGAAGCGCGGCTCCATCCCCTGCCCT
ACCGCCGCTGGCTCCGGTTCGTCAGCGCCGACGGCACCGAGTGCCGCATCCGCCTTCAGCGTGCGGGTCACATTCTCGGT
TCCGCCTATGTGGAATGCGATCTCCGCCGCCCGGGCGAGAAACCGGAGCGCATCCTGTTCTCGGGCGACCTCGGCGCACC
CCACGCACCACTGCTGCCCGCGCCGCGCCCGCCCTGGCGCGCCGACGTCGTCGTACTGGAAAGCACCTACGGCGATCGGC
TGCACGAAGGTCGGCGCGACCGCCGCCTGCGGCTGAAGAAAATCGTGGAGCACGCGCTCGATAACGGGGCACGGTAA

Upstream 100 bases:

>100_bases
TGAAGGACCTCCCGGAACGGATGTTCACCCGTGAATACATGAGCCGGCTGCAGTAGAAATCCAAATGGCATTTTGCGCGC
ATGACAAATAGAATCGTGTC

Downstream 100 bases:

>100_bases
TCATCCCCGCCTTCAGCATTGGACGCAGCCAGGAACTCCTGTACGAATTCGAGGACATCCTGCACAGGGAAAGGGCACGT
CCCGACCGGCACGCGGCACG

Product: RNA procession exonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRSEIIHHGGRDGVTGSCHQLLFGNGDSILIDCGLFQGAETAADGRGAEDALAFRMPVSAIRALVVSHVHIDHVGRIPWL
LAAGFKGPIICSEPSARLLPTVLADAFALGIARDPQLVQRYIDMVEARLHPLPYRRWLRFVSADGTECRIRLQRAGHILG
SAYVECDLRRPGEKPERILFSGDLGAPHAPLLPAPRPPWRADVVVLESTYGDRLHEGRRDRRLRLKKIVEHALDNGAR

Sequences:

>Translated_238_residues
MRSEIIHHGGRDGVTGSCHQLLFGNGDSILIDCGLFQGAETAADGRGAEDALAFRMPVSAIRALVVSHVHIDHVGRIPWL
LAAGFKGPIICSEPSARLLPTVLADAFALGIARDPQLVQRYIDMVEARLHPLPYRRWLRFVSADGTECRIRLQRAGHILG
SAYVECDLRRPGEKPERILFSGDLGAPHAPLLPAPRPPWRADVVVLESTYGDRLHEGRRDRRLRLKKIVEHALDNGAR
>Mature_238_residues
MRSEIIHHGGRDGVTGSCHQLLFGNGDSILIDCGLFQGAETAADGRGAEDALAFRMPVSAIRALVVSHVHIDHVGRIPWL
LAAGFKGPIICSEPSARLLPTVLADAFALGIARDPQLVQRYIDMVEARLHPLPYRRWLRFVSADGTECRIRLQRAGHILG
SAYVECDLRRPGEKPERILFSGDLGAPHAPLLPAPRPPWRADVVVLESTYGDRLHEGRRDRRLRLKKIVEHALDNGAR

Specific function: Has endoribonuclease activity towards 23S and 16S rRNA (in vitro) [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI7706427, Length=236, Percent_Identity=26.271186440678, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566029, Length=238, Percent_Identity=26.890756302521, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323307, Length=249, Percent_Identity=23.6947791164659, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648013, Length=234, Percent_Identity=29.0598290598291, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358523, Length=239, Percent_Identity=25.1046025104602, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 26283; Mature: 26283

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSEIIHHGGRDGVTGSCHQLLFGNGDSILIDCGLFQGAETAADGRGAEDALAFRMPVSA
CCCCCCCCCCCCCCCCHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHH
IRALVVSHVHIDHVGRIPWLLAAGFKGPIICSEPSARLLPTVLADAFALGIARDPQLVQR
HHHHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHH
YIDMVEARLHPLPYRRWLRFVSADGTECRIRLQRAGHILGSAYVECDLRRPGEKPERILF
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEHHHHCHHHHHHEEEEECCCCCCCCCEEEE
SGDLGAPHAPLLPAPRPPWRADVVVLESTYGDRLHEGRRDRRLRLKKIVEHALDNGAR
ECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSEIIHHGGRDGVTGSCHQLLFGNGDSILIDCGLFQGAETAADGRGAEDALAFRMPVSA
CCCCCCCCCCCCCCCCHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHH
IRALVVSHVHIDHVGRIPWLLAAGFKGPIICSEPSARLLPTVLADAFALGIARDPQLVQR
HHHHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHH
YIDMVEARLHPLPYRRWLRFVSADGTECRIRLQRAGHILGSAYVECDLRRPGEKPERILF
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEHHHHCHHHHHHEEEEECCCCCCCCCEEEE
SGDLGAPHAPLLPAPRPPWRADVVVLESTYGDRLHEGRRDRRLRLKKIVEHALDNGAR
ECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA