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The map label for this gene is pilC [H]

Identifier: 119899524

GI number: 119899524

Start: 3566331

End: 3567566

Strand: Direct

Name: pilC [H]

Synonym: azo3235

Alternate gene names: 119899524

Gene position: 3566331-3567566 (Clockwise)

Preceding gene: 119899523

Following gene: 119899525

Centisome position: 81.5

GC content: 59.87

Gene sequence:

>1236_bases
ATGGCGACAGCGACGCGCGCCCCGCAGCGCACCACGACGGGCCCCAGGGAGGACCTCTACAGCTGGGAAGGCAAGGACAA
GACCGGCAAGGTAATGCGCGGGGAAATGCGCGCCACCGGCGATACCGTCGTACAGGCCACGCTGCGCCGGCAGGGCATCC
AGGTCGTCAAGATCCGCAAACAGAAGCTGTCGCGCGGACACAAGATCAAGGACAAGGACATCGCACTGTTCACCCGTCAG
TTGGCGACGATGATGAAGGCCGGCGTGCCCTTGCTGCAGGCGTTCGACATCGGCATCAAAGGGTCCGGCAATCCCAGCCT
CGCCCGCCTCCTGAACGAGGTGCGTACCGATGTGGAGACGGGGTCCAGCCTGTCGCAGGCCTTCTCCAAGCATCCGGTTT
ACTTCGATAAGCTGTTCTGCAACCTGGTCGGTGCAGGCGAGCAGGCCGGCATCCTCGACAGCCTGCTGGACCGGATTGCG
ACCTATAAAGAGAAGATTCTGGCCATCAAGGGCAAGATCAAATCGGCGCTGTTTTACCCGATTGCCGTGGTCGTGGTTGC
CGCCTTGGTGATCTCGGTGATGATGTTGTTCGTCATTCCCGAGTTCAAGAGTGTCTTCACCGGGTTTGGGGCAGAACTGC
CGGGGCCAACCCTGATGGTCATTGCGATGTCAGACTTCTTTATTGAGTACTGGTATCTGCTGTTTGGTTCGATCATCGCC
GCAATCGTCGGGATCGCAGCGATATACAAACGCTCTCCCGCCATGCAGATCGCTGTCGACCGGTTGGTACTCAAACTCCC
CGTGATCGGTGATGTGATTCGCAAAGCGACGGTGGCGCGATGGGCACGCACGCTCTCCACGATGTTCTCCGCTGGCGTTC
CGTTGGTCGAGGCGCTCGATTCGGTCGGAGGTGCCGCTGGCAACTACATTTACCTGATGGCCACCAAACAGATCCAGACC
GAGGTCAGCACCGGCACCAGCCTTACTGTCTCCATGCAGAACGCTGCCGTGTTCCCCACCATGGTCGTGCAAATGGTGTC
TATCGGCGAAGAGTCCGGCCAGCTCGACTCGATGCTCGGCAAAGTGGCTGACTTCTACGAGCAGGAAGTCGATGACGCGG
TGGCGGGCCTGTCCCAGTTGCTCGAGCCACTGATCATGGTGTTCCTCGGCACGGTCATCGGCGGCCTTGTGGTGGCCATG
TATCTTCCGATCTTCAAGCTGGGCTCCATCGTCTAG

Upstream 100 bases:

>100_bases
GATCTCCGCCAGTCCGGGCTTCTCAAGGTCAAGCAGGGCGTGACGTCACTGGAAGAAGTGCTCGCCTCCACCAACGAATA
GGCAAATCGGAAAACAACCC

Downstream 100 bases:

>100_bases
CGCCGGCTCCACCCTCAAGAGCCGGCTCATCGCCGGCTACCCTCCATGCCTGAATACCTTCGCGACCCTGTCGCCTTTGC
TGCCGTCGCGACCCTGCTCG

Product: type 4 pilus biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MATATRAPQRTTTGPREDLYSWEGKDKTGKVMRGEMRATGDTVVQATLRRQGIQVVKIRKQKLSRGHKIKDKDIALFTRQ
LATMMKAGVPLLQAFDIGIKGSGNPSLARLLNEVRTDVETGSSLSQAFSKHPVYFDKLFCNLVGAGEQAGILDSLLDRIA
TYKEKILAIKGKIKSALFYPIAVVVVAALVISVMMLFVIPEFKSVFTGFGAELPGPTLMVIAMSDFFIEYWYLLFGSIIA
AIVGIAAIYKRSPAMQIAVDRLVLKLPVIGDVIRKATVARWARTLSTMFSAGVPLVEALDSVGGAAGNYIYLMATKQIQT
EVSTGTSLTVSMQNAAVFPTMVVQMVSIGEESGQLDSMLGKVADFYEQEVDDAVAGLSQLLEPLIMVFLGTVIGGLVVAM
YLPIFKLGSIV

Sequences:

>Translated_411_residues
MATATRAPQRTTTGPREDLYSWEGKDKTGKVMRGEMRATGDTVVQATLRRQGIQVVKIRKQKLSRGHKIKDKDIALFTRQ
LATMMKAGVPLLQAFDIGIKGSGNPSLARLLNEVRTDVETGSSLSQAFSKHPVYFDKLFCNLVGAGEQAGILDSLLDRIA
TYKEKILAIKGKIKSALFYPIAVVVVAALVISVMMLFVIPEFKSVFTGFGAELPGPTLMVIAMSDFFIEYWYLLFGSIIA
AIVGIAAIYKRSPAMQIAVDRLVLKLPVIGDVIRKATVARWARTLSTMFSAGVPLVEALDSVGGAAGNYIYLMATKQIQT
EVSTGTSLTVSMQNAAVFPTMVVQMVSIGEESGQLDSMLGKVADFYEQEVDDAVAGLSQLLEPLIMVFLGTVIGGLVVAM
YLPIFKLGSIV
>Mature_410_residues
ATATRAPQRTTTGPREDLYSWEGKDKTGKVMRGEMRATGDTVVQATLRRQGIQVVKIRKQKLSRGHKIKDKDIALFTRQL
ATMMKAGVPLLQAFDIGIKGSGNPSLARLLNEVRTDVETGSSLSQAFSKHPVYFDKLFCNLVGAGEQAGILDSLLDRIAT
YKEKILAIKGKIKSALFYPIAVVVVAALVISVMMLFVIPEFKSVFTGFGAELPGPTLMVIAMSDFFIEYWYLLFGSIIAA
IVGIAAIYKRSPAMQIAVDRLVLKLPVIGDVIRKATVARWARTLSTMFSAGVPLVEALDSVGGAAGNYIYLMATKQIQTE
VSTGTSLTVSMQNAAVFPTMVVQMVSIGEESGQLDSMLGKVADFYEQEVDDAVAGLSQLLEPLIMVFLGTVIGGLVVAMY
LPIFKLGSIV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=29.040404040404, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1786295, Length=393, Percent_Identity=29.0076335877863, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44476; Mature: 44345

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATATRAPQRTTTGPREDLYSWEGKDKTGKVMRGEMRATGDTVVQATLRRQGIQVVKIRK
CCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCHHHHCHHHHHHHHHHHCCHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]