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The map label for this gene is nikR [C]

Identifier: 119899418

GI number: 119899418

Start: 3436442

End: 3436924

Strand: Direct

Name: nikR [C]

Synonym: azo3128

Alternate gene names: 119899418

Gene position: 3436442-3436924 (Clockwise)

Preceding gene: 119899416

Following gene: 119899419

Centisome position: 78.53

GC content: 67.29

Gene sequence:

>483_bases
ATGGAACGCTTCACCATTTCGCTCGAGGACGAACTCGCGCGCGATTTCGACGCCCTGATCGCCGAACGCGGCTACGCCAG
CCGATCCGAAGCCGTGCGCGACATGCTGCGGCGCGAACTGGAAGCCGCCCGCCAGCGCCGCGGCGATGGAGGCCACTGCA
TCGCCAGCCTCAGCTACGTCTTCAACCATCACGAGCGCGATCTCGGCGAACGCCTGACCGGCATCCAGCACGACCACCAC
GACCTCACGGTATCCACGCTGCACGCCCATCTCGATCACGACAACTGCATCGAATCGACGATCCTGCGCGGGCCCACCGA
AGCGGTGCGGCGCTTTGCCGATTCGATCATGGCGCAAAGCGGCGTGCGCCACGGCCAGCTCAACCTGATCTCGGTGGACC
TCGCCCACCCGCAGCACGCGCACGGCCACGATCACAGCCATCCGCACGGCCCCGGCCACTTCCACTACCGCCCGCGGCGC
TGA

Upstream 100 bases:

>100_bases
TGGATAAGGCGGCCGCCGCGAGCGGCGGCGGGGCCTCGCGGCGCTGCCCAGCTTTTGGGCAAGCGGCTAAGATGAAGCCC
CCTGCCCGCGCGGAGCCGCC

Downstream 100 bases:

>100_bases
TCCGGTTCGCCGACAACGCGACGTCGCATCTGCGACAGCGCACCCCCACCCGCCGCCGACGCCTACCGCAAGCGCTTGAA
TTGACGGGCTTGCACGCCTC

Product: nickel responsive regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MERFTISLEDELARDFDALIAERGYASRSEAVRDMLRRELEAARQRRGDGGHCIASLSYVFNHHERDLGERLTGIQHDHH
DLTVSTLHAHLDHDNCIESTILRGPTEAVRRFADSIMAQSGVRHGQLNLISVDLAHPQHAHGHDHSHPHGPGHFHYRPRR

Sequences:

>Translated_160_residues
MERFTISLEDELARDFDALIAERGYASRSEAVRDMLRRELEAARQRRGDGGHCIASLSYVFNHHERDLGERLTGIQHDHH
DLTVSTLHAHLDHDNCIESTILRGPTEAVRRFADSIMAQSGVRHGQLNLISVDLAHPQHAHGHDHSHPHGPGHFHYRPRR
>Mature_160_residues
MERFTISLEDELARDFDALIAERGYASRSEAVRDMLRRELEAARQRRGDGGHCIASLSYVFNHHERDLGERLTGIQHDHH
DLTVSTLHAHLDHDNCIESTILRGPTEAVRRFADSIMAQSGVRHGQLNLISVDLAHPQHAHGHDHSHPHGPGHFHYRPRR

Specific function: Transcriptional regulator (Potential) [H]

COG id: COG0864

COG function: function code K; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory CopG/NikR family [H]

Homologues:

Organism=Escherichia coli, GI1789892, Length=131, Percent_Identity=48.8549618320611, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013321
- InterPro:   IPR002145
- InterPro:   IPR022988
- InterPro:   IPR010985
- InterPro:   IPR014864 [H]

Pfam domain/function: PF08753 NikR_C; PF01402 RHH_1 [H]

EC number: NA

Molecular weight: Translated: 18243; Mature: 18243

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFTISLEDELARDFDALIAERGYASRSEAVRDMLRRELEAARQRRGDGGHCIASLSYV
CCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FNHHERDLGERLTGIQHDHHDLTVSTLHAHLDHDNCIESTILRGPTEAVRRFADSIMAQS
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHC
GVRHGQLNLISVDLAHPQHAHGHDHSHPHGPGHFHYRPRR
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MERFTISLEDELARDFDALIAERGYASRSEAVRDMLRRELEAARQRRGDGGHCIASLSYV
CCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FNHHERDLGERLTGIQHDHHDLTVSTLHAHLDHDNCIESTILRGPTEAVRRFADSIMAQS
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHC
GVRHGQLNLISVDLAHPQHAHGHDHSHPHGPGHFHYRPRR
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA