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The map label for this gene is aroK [H]

Identifier: 119899345

GI number: 119899345

Start: 3359261

End: 3360175

Strand: Direct

Name: aroK [H]

Synonym: azo3055

Alternate gene names: 119899345

Gene position: 3359261-3360175 (Clockwise)

Preceding gene: 119899325

Following gene: 119899346

Centisome position: 76.76

GC content: 66.89

Gene sequence:

>915_bases
ATGAACACCAGGACCGAGACCCCGACCAGCCCCAACGACGCCGACCAGACCGCCGAAGCCCGCGACGAACGCGACGACGG
CGAGTTCCTGATGTCGCTCGGCAAGCGGGTGCGCGAGATCCGCGACCGCCGCGGCATGACGCGCAAGCTGGTGGCCCGCG
AGGCCGGCGTTTCCGAACGCCACCTCGCCCACCTGGAAGCCGGCGAAGGCAACGTCTCGATCGTGCTGCTGCGCCACATC
ACCCGCGCGCTGGATGTCTCGCTGATCGAGCTGCTGGCGCCGGAAGCGGAAGACACGGTGGAAAAGCGGCTGATCCGCCG
CTTCCTCGAACGGCTGCCGCAGCACCGCCTGGAAGAAGTGGTGTTCCGCCTGATGCGCGACTTCGGCCACGAAGAAGCGG
TGCGCAGGAAGCGCGTGGCGCTGATCGGCCTGCGCGGCGCGGGCAAATCCACGCTGGGCAACCGCCTGGCCAAGGAAATG
GGTGTCGGCTTCATCGAACTCGACCGCGAGATCGAGCGCGAAACCGGCATGCCGGCGAGCGAACTGTTCGCGCTGTACGG
CCAGGCGGGTTACCGCCGGATCGAGCAGCGCACGCTGGAACGGGTGATCCGTGACAACGAACGCGGCGTCATCTCGGTGG
GCGGCGGCGTCGTCGCCCAGCAGGAAACCTACGACATGCTGCTGTCGAACTGCCTGACCGTGTGGGTGAAGGCGCAGCCG
GAAGAACACATGGCCCGCGTGATGGCCCAGGGCGACCTGCGGCCGATGGCGGGCAACGACGAGGCGATGGAAGACCTCAA
GCGCATTCTCGAAGCGCGCGAGCCGCTCTACGCCAAGGCGGACACCGTGATCGACACCTCGGGCGAGACGGTGGACGAGA
GTTTCATGAAGTTAAGACAGCTCGTCATGAGCTGA

Upstream 100 bases:

>100_bases
TTTCGATGGAACTAAACTGCACTTTACCTCTTGACTCCATTTTTGAGCTGCACTATTGTTCAACAAACACGTGCTGCAGC
TCGCACAGGACGCTAACCAG

Downstream 100 bases:

>100_bases
ACCCCAAAGAAGAGGAGACAGAAAGTGGAAGCTGCAAGCGCCAACAAGATCGAACCCGTCGATTACCGCACCGAACCGTC
GCGCTACAAGCACTGGAAGC

Product: anaerobic benzoate catabolism transcriptional regulator

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNTRTETPTSPNDADQTAEARDERDDGEFLMSLGKRVREIRDRRGMTRKLVAREAGVSERHLAHLEAGEGNVSIVLLRHI
TRALDVSLIELLAPEAEDTVEKRLIRRFLERLPQHRLEEVVFRLMRDFGHEEAVRRKRVALIGLRGAGKSTLGNRLAKEM
GVGFIELDREIERETGMPASELFALYGQAGYRRIEQRTLERVIRDNERGVISVGGGVVAQQETYDMLLSNCLTVWVKAQP
EEHMARVMAQGDLRPMAGNDEAMEDLKRILEAREPLYAKADTVIDTSGETVDESFMKLRQLVMS

Sequences:

>Translated_304_residues
MNTRTETPTSPNDADQTAEARDERDDGEFLMSLGKRVREIRDRRGMTRKLVAREAGVSERHLAHLEAGEGNVSIVLLRHI
TRALDVSLIELLAPEAEDTVEKRLIRRFLERLPQHRLEEVVFRLMRDFGHEEAVRRKRVALIGLRGAGKSTLGNRLAKEM
GVGFIELDREIERETGMPASELFALYGQAGYRRIEQRTLERVIRDNERGVISVGGGVVAQQETYDMLLSNCLTVWVKAQP
EEHMARVMAQGDLRPMAGNDEAMEDLKRILEAREPLYAKADTVIDTSGETVDESFMKLRQLVMS
>Mature_304_residues
MNTRTETPTSPNDADQTAEARDERDDGEFLMSLGKRVREIRDRRGMTRKLVAREAGVSERHLAHLEAGEGNVSIVLLRHI
TRALDVSLIELLAPEAEDTVEKRLIRRFLERLPQHRLEEVVFRLMRDFGHEEAVRRKRVALIGLRGAGKSTLGNRLAKEM
GVGFIELDREIERETGMPASELFALYGQAGYRRIEQRTLERVIRDNERGVISVGGGVVAQQETYDMLLSNCLTVWVKAQP
EEHMARVMAQGDLRPMAGNDEAMEDLKRILEAREPLYAKADTVIDTSGETVDESFMKLRQLVMS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=156, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786587, Length=152, Percent_Identity=30.2631578947368, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 34493; Mature: 34493

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50943 HTH_CROC1 ; PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRTETPTSPNDADQTAEARDERDDGEFLMSLGKRVREIRDRRGMTRKLVAREAGVSER
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHH
HLAHLEAGEGNVSIVLLRHITRALDVSLIELLAPEAEDTVEKRLIRRFLERLPQHRLEEV
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFRLMRDFGHEEAVRRKRVALIGLRGAGKSTLGNRLAKEMGVGFIELDREIERETGMPAS
HHHHHHHHCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
ELFALYGQAGYRRIEQRTLERVIRDNERGVISVGGGVVAQQETYDMLLSNCLTVWVKAQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCC
EEHMARVMAQGDLRPMAGNDEAMEDLKRILEAREPLYAKADTVIDTSGETVDESFMKLRQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCEECCCCCHHHHHHHHHHH
LVMS
HHCC
>Mature Secondary Structure
MNTRTETPTSPNDADQTAEARDERDDGEFLMSLGKRVREIRDRRGMTRKLVAREAGVSER
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHH
HLAHLEAGEGNVSIVLLRHITRALDVSLIELLAPEAEDTVEKRLIRRFLERLPQHRLEEV
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFRLMRDFGHEEAVRRKRVALIGLRGAGKSTLGNRLAKEMGVGFIELDREIERETGMPAS
HHHHHHHHCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
ELFALYGQAGYRRIEQRTLERVIRDNERGVISVGGGVVAQQETYDMLLSNCLTVWVKAQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCC
EEHMARVMAQGDLRPMAGNDEAMEDLKRILEAREPLYAKADTVIDTSGETVDESFMKLRQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCEECCCCCHHHHHHHHHHH
LVMS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA