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The map label for this gene is fdh1B [H]

Identifier: 119899329

GI number: 119899329

Start: 3342156

End: 3343871

Strand: Reverse

Name: fdh1B [H]

Synonym: azo3039

Alternate gene names: 119899329

Gene position: 3343871-3342156 (Counterclockwise)

Preceding gene: 119899330

Following gene: 119899328

Centisome position: 76.41

GC content: 71.45

Gene sequence:

>1716_bases
ATGACCGAAGCAAACCGAGCGATCTCCCCCAGCCGCGGCCGTGGCCGGCCGCCCTTGCCCGAGGCGGCGCGCGCCGCGGC
AAACGCCGCGCTGGCCGGCGAAACCCCGCGTGCCGACCGCCTGATCGAATACCTGCACCGCCTGCAGGATGCCCACGGCG
CGCTCTACGCCGACCACCTCGCCGCGCTCGCCGAGGCGATGAAGCTGGCGCAGGCGGAGGTCTATGAGGTCGCCACCTTC
TACCACCACTTCGACGTGGTGCCCGCCGGCGAAACGCCGCCGCCGCTGCTCACGGTGCGGGTGTGCGATTCGCTGACCTG
CGCGCTCTACGGCGGGCCGGAACTCGCCGCCGAACTCCAAGGCCGGCTGGGCGCGGAGGTGCGGGTGCAGCGCGTGCCCT
GTGTCGGCCGCTGCGACTGCGCGCCGGTGGCGGTGGTGGGGCAGAACCCGGTGATGCACGCCGATGCCGACAAGGTGGCC
GCGGCGGTGGCGGCCGGCGAGCGCGAGGAAGCCGCGCCGGAGATCATCGACTTCGACGCCTACCGTGCCGATGGCGGCTA
CCGGCTGTATGAGTCTGTGGTACGCGGCGAGCACGACGCGGAGGAGGTGCTTGGCGTGCTCGATACCGCCATCCTGCGCG
GCCTCGGCGGCGCGGGTTTTCCGGCGGCGCGCAAGTGGCGCACGGTGATGGCGCAGCCGGCGCCGCGCAACATGGCGGTG
AACATCGACGAAGGCGAACCCGGCACCTTCAAGGACCGCCACTACCTCGGCCGCGACCCGCACCGCTTCCTCGAAGGCAT
GCTGATCGCCGCCCGCGTGGTCGGCATCTCGGCGATCTGGATCTACATCCGCGACGAATACCCAGCGCTGCGCCGCATGC
TGCTCGCCGAACTCGACAAGCTGCGTGCGGCGTGGCCGGATTTGCCGCCGGTCGAGCTGCGCCGCGGCGCCGGCGCCTAC
ATCTGCGGCGAAGAGTCGGCGATGATCGAATCCATCGAGGGCAAGCGCGGCATGCCGCGGCTGCGTCCGCCCTATGTGGC
CGAGGTGGGCCTGTTTGGCCGGCCGACCCTGGTGCACAACCCGGAAACCCTGTGGTGGGTGCGCGACATCGTCACCGCCG
GCCTGGTGCAGGGGGCGCAGTGGCTGGAAGGCCGCGGCCGCAACGGCCGCCGCGGGCTGCGCAGCTTTTCGGTGAGCGGC
CGGGTGGCGAAACCCGGCGTGGTCGTCACCGACGCCGGTATCACCCTGCGCCAGCTGGTCGACGAGCACTGCGGCGGCAT
GCTGCCGGGGCACGAGTTGTACGGCTATTTCCCCGGCGGCGCCTCGGGCGGCATCCTGCCCGCCAGCCTTGCCGACGTGC
CGTTGGACTTCGACACGCTGGCGCCCTACGGCTGTTTCATCGGCTCGGCGGCGATCGTCGTGTTCTCGCAGCACGACCAG
GCGCGCGTGCTGGCGGAGAACGCGATGCACTTCTTCGCCCATGAATCCTGCGGCCAATGCACGCCCTGCCGCGTCGGTAC
CGCCAAGGCCGCCGACCTGATGGCCGCGCCCACCTGGGATGCCGGCCTGCTCGACGAACTCGGCAGCGCGATGATGGACG
CCTCGATCTGCGGCCTCGGCCAGGCCGCGCCCAACCCGATGCGCTCGGTGCTGCGCTACTTCCCGCAGGAAGTCGGCGCA
GTGCGCGCAAGCGAACAGAAGGAGGGCGCAGCATGA

Upstream 100 bases:

>100_bases
TCTCAACCCCCAAGCCCGCCGGCTTGCACCCGCGAGCAAAAGCTCCGCTCATTCCTCCAGCGTCACCCGCCAGTTCCCGC
ATCAACAACGGACCAAAAGC

Downstream 100 bases:

>100_bases
ACGCCCCCGACACCATTACCTTCGAACTCGACGGCCGCGCGGTGGACGCCGCGCCCGGCGAATCCATCCTGCTCGCCGCC
CGCCGCGCCGGCGTGGATAT

Product: formate dehydrogenase (NADP+) subunit beta

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTEANRAISPSRGRGRPPLPEAARAAANAALAGETPRADRLIEYLHRLQDAHGALYADHLAALAEAMKLAQAEVYEVATF
YHHFDVVPAGETPPPLLTVRVCDSLTCALYGGPELAAELQGRLGAEVRVQRVPCVGRCDCAPVAVVGQNPVMHADADKVA
AAVAAGEREEAAPEIIDFDAYRADGGYRLYESVVRGEHDAEEVLGVLDTAILRGLGGAGFPAARKWRTVMAQPAPRNMAV
NIDEGEPGTFKDRHYLGRDPHRFLEGMLIAARVVGISAIWIYIRDEYPALRRMLLAELDKLRAAWPDLPPVELRRGAGAY
ICGEESAMIESIEGKRGMPRLRPPYVAEVGLFGRPTLVHNPETLWWVRDIVTAGLVQGAQWLEGRGRNGRRGLRSFSVSG
RVAKPGVVVTDAGITLRQLVDEHCGGMLPGHELYGYFPGGASGGILPASLADVPLDFDTLAPYGCFIGSAAIVVFSQHDQ
ARVLAENAMHFFAHESCGQCTPCRVGTAKAADLMAAPTWDAGLLDELGSAMMDASICGLGQAAPNPMRSVLRYFPQEVGA
VRASEQKEGAA

Sequences:

>Translated_571_residues
MTEANRAISPSRGRGRPPLPEAARAAANAALAGETPRADRLIEYLHRLQDAHGALYADHLAALAEAMKLAQAEVYEVATF
YHHFDVVPAGETPPPLLTVRVCDSLTCALYGGPELAAELQGRLGAEVRVQRVPCVGRCDCAPVAVVGQNPVMHADADKVA
AAVAAGEREEAAPEIIDFDAYRADGGYRLYESVVRGEHDAEEVLGVLDTAILRGLGGAGFPAARKWRTVMAQPAPRNMAV
NIDEGEPGTFKDRHYLGRDPHRFLEGMLIAARVVGISAIWIYIRDEYPALRRMLLAELDKLRAAWPDLPPVELRRGAGAY
ICGEESAMIESIEGKRGMPRLRPPYVAEVGLFGRPTLVHNPETLWWVRDIVTAGLVQGAQWLEGRGRNGRRGLRSFSVSG
RVAKPGVVVTDAGITLRQLVDEHCGGMLPGHELYGYFPGGASGGILPASLADVPLDFDTLAPYGCFIGSAAIVVFSQHDQ
ARVLAENAMHFFAHESCGQCTPCRVGTAKAADLMAAPTWDAGLLDELGSAMMDASICGLGQAAPNPMRSVLRYFPQEVGA
VRASEQKEGAA
>Mature_570_residues
TEANRAISPSRGRGRPPLPEAARAAANAALAGETPRADRLIEYLHRLQDAHGALYADHLAALAEAMKLAQAEVYEVATFY
HHFDVVPAGETPPPLLTVRVCDSLTCALYGGPELAAELQGRLGAEVRVQRVPCVGRCDCAPVAVVGQNPVMHADADKVAA
AVAAGEREEAAPEIIDFDAYRADGGYRLYESVVRGEHDAEEVLGVLDTAILRGLGGAGFPAARKWRTVMAQPAPRNMAVN
IDEGEPGTFKDRHYLGRDPHRFLEGMLIAARVVGISAIWIYIRDEYPALRRMLLAELDKLRAAWPDLPPVELRRGAGAYI
CGEESAMIESIEGKRGMPRLRPPYVAEVGLFGRPTLVHNPETLWWVRDIVTAGLVQGAQWLEGRGRNGRRGLRSFSVSGR
VAKPGVVVTDAGITLRQLVDEHCGGMLPGHELYGYFPGGASGGILPASLADVPLDFDTLAPYGCFIGSAAIVVFSQHDQA
RVLAENAMHFFAHESCGQCTPCRVGTAKAADLMAAPTWDAGLLDELGSAMMDASICGLGQAAPNPMRSVLRYFPQEVGAV
RASEQKEGAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=392, Percent_Identity=38.5204081632653, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI260656005, Length=392, Percent_Identity=38.5204081632653, Blast_Score=242, Evalue=5e-64,
Organism=Escherichia coli, GI1788620, Length=413, Percent_Identity=32.2033898305085, Blast_Score=197, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17531727, Length=403, Percent_Identity=38.7096774193548, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI19920794, Length=392, Percent_Identity=39.2857142857143, Blast_Score=255, Evalue=7e-68,
Organism=Drosophila melanogaster, GI45550452, Length=387, Percent_Identity=34.3669250645995, Blast_Score=215, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24653819, Length=405, Percent_Identity=31.1111111111111, Blast_Score=182, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24653817, Length=359, Percent_Identity=30.6406685236769, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 61246; Mature: 61114

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEANRAISPSRGRGRPPLPEAARAAANAALAGETPRADRLIEYLHRLQDAHGALYADHL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
AALAEAMKLAQAEVYEVATFYHHFDVVPAGETPPPLLTVRVCDSLTCALYGGPELAAELQ
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCEEEEEECCHHHHHHHH
GRLGAEVRVQRVPCVGRCDCAPVAVVGQNPVMHADADKVAAAVAAGEREEAAPEIIDFDA
HCCCCCEEEEECCCCCCCCCCCEEEECCCCCEECCHHHHHHHHHCCCHHHCCCCEEECCC
YRADGGYRLYESVVRGEHDAEEVLGVLDTAILRGLGGAGFPAARKWRTVMAQPAPRNMAV
EECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEE
NIDEGEPGTFKDRHYLGRDPHRFLEGMLIAARVVGISAIWIYIRDEYPALRRMLLAELDK
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHHH
LRAAWPDLPPVELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAEVGLFGRPTLVHN
HHHCCCCCCHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCEEEC
PETLWWVRDIVTAGLVQGAQWLEGRGRNGRRGLRSFSVSGRVAKPGVVVTDAGITLRQLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHHH
DEHCGGMLPGHELYGYFPGGASGGILPASLADVPLDFDTLAPYGCFIGSAAIVVFSQHDQ
HHHHCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCHHHCCCHHHHHCCEEEEEEECCCH
ARVLAENAMHFFAHESCGQCTPCRVGTAKAADLMAAPTWDAGLLDELGSAMMDASICGLG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
QAAPNPMRSVLRYFPQEVGAVRASEQKEGAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TEANRAISPSRGRGRPPLPEAARAAANAALAGETPRADRLIEYLHRLQDAHGALYADHL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
AALAEAMKLAQAEVYEVATFYHHFDVVPAGETPPPLLTVRVCDSLTCALYGGPELAAELQ
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCEEEEEECCHHHHHHHH
GRLGAEVRVQRVPCVGRCDCAPVAVVGQNPVMHADADKVAAAVAAGEREEAAPEIIDFDA
HCCCCCEEEEECCCCCCCCCCCEEEECCCCCEECCHHHHHHHHHCCCHHHCCCCEEECCC
YRADGGYRLYESVVRGEHDAEEVLGVLDTAILRGLGGAGFPAARKWRTVMAQPAPRNMAV
EECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEE
NIDEGEPGTFKDRHYLGRDPHRFLEGMLIAARVVGISAIWIYIRDEYPALRRMLLAELDK
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHHH
LRAAWPDLPPVELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAEVGLFGRPTLVHN
HHHCCCCCCHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCEEEC
PETLWWVRDIVTAGLVQGAQWLEGRGRNGRRGLRSFSVSGRVAKPGVVVTDAGITLRQLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHHH
DEHCGGMLPGHELYGYFPGGASGGILPASLADVPLDFDTLAPYGCFIGSAAIVVFSQHDQ
HHHHCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCHHHCCCHHHHHCCEEEEEEECCCH
ARVLAENAMHFFAHESCGQCTPCRVGTAKAADLMAAPTWDAGLLDELGSAMMDASICGLG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
QAAPNPMRSVLRYFPQEVGAVRASEQKEGAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]