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The map label for this gene is etf2 [C]

Identifier: 119899298

GI number: 119899298

Start: 3305802

End: 3307487

Strand: Direct

Name: etf2 [C]

Synonym: azo3008

Alternate gene names: 119899298

Gene position: 3305802-3307487 (Clockwise)

Preceding gene: 119899297

Following gene: 119899300

Centisome position: 75.54

GC content: 69.57

Gene sequence:

>1686_bases
ATGACCCCGCAAGACCTCCTCGACCACTACGGCCCGCGCGAATCCACCACCTACGACGTCGCCATCGTCGGTGCCGGCCC
GGCCGGCCTCGCCACCGCCATCCGCCTCAAGCAGCTGGCCGCCGAACGCGGCGGCGAAATCTCCGTCGTCGTTCTCGAAA
AGGGCTCCGAACCCGGCGCCCACATCCTCAGCGGCGCCGTCATGGACCCGCGCGCGCTCGACGAGCTGATTCCCGACTGG
AAGGAACGCGGCGCGCCGCTGCATCAGCCGGTCACCGCCGACGAAGTGCTGCTGCTCTCGGAAACCGGCGCGTGGCGGAC
GCCTGCCGCGCTGGTGCCGCACAACTTCCACAACGCGGGCAACTACGTCGTCAGCCTCGGCAAGGTGGTGCGCTGGCTGG
CCGTGCAGGCCGAAGCCCTGGGCGTCGACATCTTCCCCGGCTTCGCCGCCGCCGAAGTCCTCTACAACGAGGATGGCGCA
GTCAAGGGCGTGGCCACCGGCAACATGGGCATCGGCAGGGACGGAGCGCCGGGGGCCGACTTCCAGCTGGGCATGGAGCT
GCACGCCGGCTACACCGTGTTCGCCGAAGGCGCGCGCGGCCAGCTCGGGCGCCAGCTGCTGGAGCGCTTCCGGCTGCAGG
ACGGCAAGGCGCCGCAGAGCTTCGGCATCGGCATCAAGGAACTGTGGGAAATCCCGGCCGAGCGCGCCCGCCCCGGCCTG
GTGGTGCACACCGCCGGCTGGCCGATGGACACGCACACCTTCGGCGGCGGCTTCCTCTACCACCTGGAGAACAACCAGGT
CGCGCTCGGCTTCGTCGTCGGGCTGGATTACCGCAACCCCTGGCTCAGCCCGTTCGAGGAGATGCAGCGCTGGAAGCAGC
ATCCGGCCATCCGGCGCCACATCGAAGGCGGCCGGCGGCTGGGCTACGGCGCGCGCGCCATCAACAACGGCGGCATCCCC
AGCCTGCCGAAGACGGTGTTTCCCGGCGGGGCGCTGGTCGGCTGCGACGCCGGCTACCTGAATGCCAGCCGCATCAAGGG
CAGCCACGCCGCGATCAAGAGCGGCATGCTGGCGGCCGAGGCCATCCATGAAGCACTGGCCGCCGGGCGCAGCCACGACG
AACTCGCCGCCTACCCCGCAGCCTTCGAGCGCAGCTGGCTGTACCGCGAACTGCGCGCGGCGAGCAACTTCAAGCCGTGG
TTCAAGAAGGGACGCACCGTCGGCATGCTGATGGCCGGCGTCGAACACTGGCTGCTGCCGCGGCTGGGCATCGCGACACC
GCCATGGACGCTGCGCAATCCGGCCCCCGATCACGGCTTCCTCGCCGCGGCGGCGGACTGCCCGAAAATCGACTACCCCA
AACCCGACGGCAGGATCAGCTTCGACCGGCTGTCCTCGGTGTTCCTCTCCAACACCAACCATGCCGAGAACCAGCCGGCG
CACCTGACGCTGAAGGATGCGGACGTGCCGCTGGCGATCAACCGGGCCCGCTACGCCGGACCGGAAGCGCGCTACTGCCC
CGCCGGGGTGTATGAATTCGTGGCCGACGACGCCGGCCGCGAACGCCTGCAGATCAACGCGCAGAACTGCGTGCACTGCA
AGACCTGCGACATCAAGGACCCCACGCAGAACATCGTGTGGTGCGCCCCCGAAGGCGGTGGCGGCCCGAACTACACCGGA
CTGTAA

Upstream 100 bases:

>100_bases
TCCGCGCAGCCCGTGCGGCACGCCTGCCTGCAGGCGCTGCAGCCGGATGCCAGCCTGATCCAGGTCTCCTTCCACCGGCA
CTGACGCCACCGACATCGCC

Downstream 100 bases:

>100_bases
GCCCCGCCCCTTCCAGCGGCAGCGCCGCGGCAACCGCCGCCGCGCTGCCGTTTTTCATTGCTGGCAGCCCCATGAAGCCC
CCCTATGGGGTGAAGCAGGG

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTPQDLLDHYGPRESTTYDVAIVGAGPAGLATAIRLKQLAAERGGEISVVVLEKGSEPGAHILSGAVMDPRALDELIPDW
KERGAPLHQPVTADEVLLLSETGAWRTPAALVPHNFHNAGNYVVSLGKVVRWLAVQAEALGVDIFPGFAAAEVLYNEDGA
VKGVATGNMGIGRDGAPGADFQLGMELHAGYTVFAEGARGQLGRQLLERFRLQDGKAPQSFGIGIKELWEIPAERARPGL
VVHTAGWPMDTHTFGGGFLYHLENNQVALGFVVGLDYRNPWLSPFEEMQRWKQHPAIRRHIEGGRRLGYGARAINNGGIP
SLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKSGMLAAEAIHEALAAGRSHDELAAYPAAFERSWLYRELRAASNFKPW
FKKGRTVGMLMAGVEHWLLPRLGIATPPWTLRNPAPDHGFLAAAADCPKIDYPKPDGRISFDRLSSVFLSNTNHAENQPA
HLTLKDADVPLAINRARYAGPEARYCPAGVYEFVADDAGRERLQINAQNCVHCKTCDIKDPTQNIVWCAPEGGGGPNYTG
L

Sequences:

>Translated_561_residues
MTPQDLLDHYGPRESTTYDVAIVGAGPAGLATAIRLKQLAAERGGEISVVVLEKGSEPGAHILSGAVMDPRALDELIPDW
KERGAPLHQPVTADEVLLLSETGAWRTPAALVPHNFHNAGNYVVSLGKVVRWLAVQAEALGVDIFPGFAAAEVLYNEDGA
VKGVATGNMGIGRDGAPGADFQLGMELHAGYTVFAEGARGQLGRQLLERFRLQDGKAPQSFGIGIKELWEIPAERARPGL
VVHTAGWPMDTHTFGGGFLYHLENNQVALGFVVGLDYRNPWLSPFEEMQRWKQHPAIRRHIEGGRRLGYGARAINNGGIP
SLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKSGMLAAEAIHEALAAGRSHDELAAYPAAFERSWLYRELRAASNFKPW
FKKGRTVGMLMAGVEHWLLPRLGIATPPWTLRNPAPDHGFLAAAADCPKIDYPKPDGRISFDRLSSVFLSNTNHAENQPA
HLTLKDADVPLAINRARYAGPEARYCPAGVYEFVADDAGRERLQINAQNCVHCKTCDIKDPTQNIVWCAPEGGGGPNYTG
L
>Mature_560_residues
TPQDLLDHYGPRESTTYDVAIVGAGPAGLATAIRLKQLAAERGGEISVVVLEKGSEPGAHILSGAVMDPRALDELIPDWK
ERGAPLHQPVTADEVLLLSETGAWRTPAALVPHNFHNAGNYVVSLGKVVRWLAVQAEALGVDIFPGFAAAEVLYNEDGAV
KGVATGNMGIGRDGAPGADFQLGMELHAGYTVFAEGARGQLGRQLLERFRLQDGKAPQSFGIGIKELWEIPAERARPGLV
VHTAGWPMDTHTFGGGFLYHLENNQVALGFVVGLDYRNPWLSPFEEMQRWKQHPAIRRHIEGGRRLGYGARAINNGGIPS
LPKTVFPGGALVGCDAGYLNASRIKGSHAAIKSGMLAAEAIHEALAAGRSHDELAAYPAAFERSWLYRELRAASNFKPWF
KKGRTVGMLMAGVEHWLLPRLGIATPPWTLRNPAPDHGFLAAAADCPKIDYPKPDGRISFDRLSSVFLSNTNHAENQPAH
LTLKDADVPLAINRARYAGPEARYCPAGVYEFVADDAGRERLQINAQNCVHCKTCDIKDPTQNIVWCAPEGGGGPNYTGL

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=554, Percent_Identity=53.7906137184115, Blast_Score=602, Evalue=1e-172,
Organism=Escherichia coli, GI1787991, Length=394, Percent_Identity=29.4416243654822, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786227, Length=433, Percent_Identity=27.4826789838337, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87082155, Length=366, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144720, Length=561, Percent_Identity=53.1194295900178, Blast_Score=602, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6324932, Length=588, Percent_Identity=43.7074829931973, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24652256, Length=552, Percent_Identity=55.2536231884058, Blast_Score=601, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 60530; Mature: 60399

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQDLLDHYGPRESTTYDVAIVGAGPAGLATAIRLKQLAAERGGEISVVVLEKGSEPGA
CCHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
HILSGAVMDPRALDELIPDWKERGAPLHQPVTADEVLLLSETGAWRTPAALVPHNFHNAG
HHHHCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
NYVVSLGKVVRWLAVQAEALGVDIFPGFAAAEVLYNEDGAVKGVATGNMGIGRDGAPGAD
HHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCCCC
FQLGMELHAGYTVFAEGARGQLGRQLLERFRLQDGKAPQSFGIGIKELWEIPAERARPGL
EEECEEEECCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHCCHHHCCCCE
VVHTAGWPMDTHTFGGGFLYHLENNQVALGFVVGLDYRNPWLSPFEEMQRWKQHPAIRRH
EEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHCHHHHHH
IEGGRRLGYGARAINNGGIPSLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKSGMLAAE
HCCCCEECCCCEEECCCCCCCCCHHHCCCCEEEECCCCCCCHHHCCCHHHHHHHCHHHHH
AIHEALAAGRSHDELAAYPAAFERSWLYRELRAASNFKPWFKKGRTVGMLMAGVEHWLLP
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
RLGIATPPWTLRNPAPDHGFLAAAADCPKIDYPKPDGRISFDRLSSVFLSNTNHAENQPA
HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCC
HLTLKDADVPLAINRARYAGPEARYCPAGVYEFVADDAGRERLQINAQNCVHCKTCDIKD
EEEEECCCCCEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCEEEEECCCCC
PTQNIVWCAPEGGGGPNYTGL
CCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TPQDLLDHYGPRESTTYDVAIVGAGPAGLATAIRLKQLAAERGGEISVVVLEKGSEPGA
CHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
HILSGAVMDPRALDELIPDWKERGAPLHQPVTADEVLLLSETGAWRTPAALVPHNFHNAG
HHHHCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
NYVVSLGKVVRWLAVQAEALGVDIFPGFAAAEVLYNEDGAVKGVATGNMGIGRDGAPGAD
HHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCCCC
FQLGMELHAGYTVFAEGARGQLGRQLLERFRLQDGKAPQSFGIGIKELWEIPAERARPGL
EEECEEEECCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHCCHHHCCCCE
VVHTAGWPMDTHTFGGGFLYHLENNQVALGFVVGLDYRNPWLSPFEEMQRWKQHPAIRRH
EEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHCHHHHHH
IEGGRRLGYGARAINNGGIPSLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKSGMLAAE
HCCCCEECCCCEEECCCCCCCCCHHHCCCCEEEECCCCCCCHHHCCCHHHHHHHCHHHHH
AIHEALAAGRSHDELAAYPAAFERSWLYRELRAASNFKPWFKKGRTVGMLMAGVEHWLLP
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
RLGIATPPWTLRNPAPDHGFLAAAADCPKIDYPKPDGRISFDRLSSVFLSNTNHAENQPA
HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCC
HLTLKDADVPLAINRARYAGPEARYCPAGVYEFVADDAGRERLQINAQNCVHCKTCDIKD
EEEEECCCCCEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCEEEEECCCCC
PTQNIVWCAPEGGGGPNYTGL
CCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]