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The map label for this gene is etfA4 [H]

Identifier: 119899296

GI number: 119899296

Start: 3304218

End: 3305165

Strand: Direct

Name: etfA4 [H]

Synonym: azo3006

Alternate gene names: 119899296

Gene position: 3304218-3305165 (Clockwise)

Preceding gene: 119899295

Following gene: 119899297

Centisome position: 75.51

GC content: 75.95

Gene sequence:

>948_bases
ATGAACGCCCTCATCATCGCCGCCCACGACGGCCAGCAGCTCGACCCCGCCACCGCCTGCGCGGTCACCGCAGCCCGGCC
CCTGGCCGCCAACGGCCGCATCGACATCCTCGTCGTCGGCCACGACACCGCGGCCGTCGCCGCCCAGGCCGCGGCGCTGG
TCGGCGTCGCCAGCGTGCGGGTGGCCGATTCCCCGGCGCTGGGCGCGCCCAATGCCGAAACCCTGGCGCGCCAGATCACC
GCGGTGGCCGCCGGCTATGCCTGGGTGCTGGCCGCGCACAACCTGCAGGCCCGCGCCGCGCTGCCGCGCGCGGCGGCGCT
GGCTGGCGCCGCCTACCTGAGCGACGTGGTGCGCACCGCCGCCGACGCGCTCGAACGCCCGGCCTATGCCGGCGCGGTGG
TGACGCGGGTCCGGCCGCTCGCCGCCGCCACCTTCCTCACCGTGCGCGCCAGCGCCTTTCCCGCCGCCGCGGCCGCATCG
GCACCGGCCCCGATCGAAGCAGTCGCCGCCGTCGAGGCGGATGCCCGCACCCGCATCCTCGGCAGCGAGGGCGGCGCCAG
CACCCGCCCCGACCTGAGCCGCGCGCGCATCGTGGTGGCGGGCGGGCGCGGCGTGGGCTCGGCGGAGAACATGGCGAAGG
TCGAAGCGCTGGCCGACCATCTGGGCGCCGCGGTGGGCGCGTCGCGCGCGGCGGTCGATGCCGGCTTCGCCCCCAACGCG
GTGCAGATCGGCCAGACCGGCAAGGTGGTCGCGCCCGACCTGTATCTGGCGCTGGGCATCTCCGGCGCCATCCAGCACCT
GGCCGGCATCAAGGACGCCAAGTGCATCGTCGCCATCAACAAGGACCCGGACGCGCCGATCTTCCAGATCGCCGACTACG
GCATCGTCGGCGATCTGTTCGAAGCGCTGCCGGTGCTGCAGGCGCAGCTCGCGGCCGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCGCGCGCGCGCCCGGCATCAAGCTGGACAGCCTGGCCGCGCTGATCGAACGCCTGCGCGCCCTGCCCGCCCTGCAATC
CTGATCCCCGGAGCCCCGCC

Downstream 100 bases:

>100_bases
GCCGGTCGGCGATGACTGCCGCCGCAGCGCGCCCCTTCGTGCTCGCCGCCATCGCGCCGCAACCGTGGCGCAACGGCGGC
GGCGCCACCCGCGAGATCCT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNALIIAAHDGQQLDPATACAVTAARPLAANGRIDILVVGHDTAAVAAQAAALVGVASVRVADSPALGAPNAETLARQIT
AVAAGYAWVLAAHNLQARAALPRAAALAGAAYLSDVVRTAADALERPAYAGAVVTRVRPLAAATFLTVRASAFPAAAAAS
APAPIEAVAAVEADARTRILGSEGGASTRPDLSRARIVVAGGRGVGSAENMAKVEALADHLGAAVGASRAAVDAGFAPNA
VQIGQTGKVVAPDLYLALGISGAIQHLAGIKDAKCIVAINKDPDAPIFQIADYGIVGDLFEALPVLQAQLAAAAA

Sequences:

>Translated_315_residues
MNALIIAAHDGQQLDPATACAVTAARPLAANGRIDILVVGHDTAAVAAQAAALVGVASVRVADSPALGAPNAETLARQIT
AVAAGYAWVLAAHNLQARAALPRAAALAGAAYLSDVVRTAADALERPAYAGAVVTRVRPLAAATFLTVRASAFPAAAAAS
APAPIEAVAAVEADARTRILGSEGGASTRPDLSRARIVVAGGRGVGSAENMAKVEALADHLGAAVGASRAAVDAGFAPNA
VQIGQTGKVVAPDLYLALGISGAIQHLAGIKDAKCIVAINKDPDAPIFQIADYGIVGDLFEALPVLQAQLAAAAA
>Mature_315_residues
MNALIIAAHDGQQLDPATACAVTAARPLAANGRIDILVVGHDTAAVAAQAAALVGVASVRVADSPALGAPNAETLARQIT
AVAAGYAWVLAAHNLQARAALPRAAALAGAAYLSDVVRTAADALERPAYAGAVVTRVRPLAAATFLTVRASAFPAAAAAS
APAPIEAVAAVEADARTRILGSEGGASTRPDLSRARIVVAGGRGVGSAENMAKVEALADHLGAAVGASRAAVDAGFAPNA
VQIGQTGKVVAPDLYLALGISGAIQHLAGIKDAKCIVAINKDPDAPIFQIADYGIVGDLFEALPVLQAQLAAAAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=308, Percent_Identity=43.5064935064935, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=45.2830188679245, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI1786226, Length=188, Percent_Identity=39.3617021276596, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787990, Length=161, Percent_Identity=42.8571428571429, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082157, Length=119, Percent_Identity=42.0168067226891, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=45.6869009584665, Blast_Score=243, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6325261, Length=229, Percent_Identity=43.6681222707424, Blast_Score=182, Evalue=7e-47,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=41.85303514377, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=41.85303514377, Blast_Score=234, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31133; Mature: 31133

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALIIAAHDGQQLDPATACAVTAARPLAANGRIDILVVGHDTAAVAAQAAALVGVASVR
CCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHEE
VADSPALGAPNAETLARQITAVAAGYAWVLAAHNLQARAALPRAAALAGAAYLSDVVRTA
EECCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHH
ADALERPAYAGAVVTRVRPLAAATFLTVRASAFPAAAAASAPAPIEAVAAVEADARTRIL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHECCCCCCHHCCCCCCCHHHHHHHCCCCCEEEE
GSEGGASTRPDLSRARIVVAGGRGVGSAENMAKVEALADHLGAAVGASRAAVDAGFAPNA
ECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCE
VQIGQTGKVVAPDLYLALGISGAIQHLAGIKDAKCIVAINKDPDAPIFQIADYGIVGDLF
EEECCCCCEECCCHHEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHH
EALPVLQAQLAAAAA
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNALIIAAHDGQQLDPATACAVTAARPLAANGRIDILVVGHDTAAVAAQAAALVGVASVR
CCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHEE
VADSPALGAPNAETLARQITAVAAGYAWVLAAHNLQARAALPRAAALAGAAYLSDVVRTA
EECCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHH
ADALERPAYAGAVVTRVRPLAAATFLTVRASAFPAAAAASAPAPIEAVAAVEADARTRIL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHECCCCCCHHCCCCCCCHHHHHHHCCCCCEEEE
GSEGGASTRPDLSRARIVVAGGRGVGSAENMAKVEALADHLGAAVGASRAAVDAGFAPNA
ECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCE
VQIGQTGKVVAPDLYLALGISGAIQHLAGIKDAKCIVAINKDPDAPIFQIADYGIVGDLF
EEECCCCCEECCCHHEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHH
EALPVLQAQLAAAAA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]