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The map label for this gene is copR [H]

Identifier: 119899236

GI number: 119899236

Start: 3233236

End: 3233916

Strand: Reverse

Name: copR [H]

Synonym: azo2946

Alternate gene names: 119899236

Gene position: 3233916-3233236 (Counterclockwise)

Preceding gene: 119899248

Following gene: 119899235

Centisome position: 73.9

GC content: 68.72

Gene sequence:

>681_bases
GTGAAGATCCTGATCGTCGAGGACGAGCCCAAGACCGGCGACTACCTGCGCCAGGGGTTGGCCGAGGCGGGCTTCGTCGT
CGATCTGGCGCGCGACGGCCTGGACGGCCTGCACCTTGCGCTCGGCGGCGACTACGACCTTGTGGTGCTCGATGTGATGC
TGCCTTCGCTCGACGGCTGGGGCGTGCTGCAGACCGTGCGCCGCGCCGGCCACGAGATGCCGGTGCTGTTCCTGACCGCG
CGCGATCAGGTCGAGGACCGTGTGCGCGGGCTTGAACTCGGCGCTGACGACTACCTGGTCAAGCCCTTCGCCTTCTCCGA
ACTGCTCGCCCGGGTGCGGACCCTGTTGCGCCGTGGCAAGGCCAAGGAGGCCGAAGTGCTGCGCGCGGCCGACCTCGAAC
TGGACCTGCTGCGCCGGCGGGTGGTCCGCGGCGGCCAGCGCATCGACCTCACCGCCAAGGAATTCGCTCTGCTCGAACTG
CTGCTGCGCCGCCAGGGCGAGGTGCTGCCGCGCTCGCTGATCGCTTCGCAGGTGTGGGACATGAATTTCGACAGCGACAC
CAACGTCATCGAGGTGGCGGTGCGCCGGTTGCGCGCGAAGGTGGACGACAGCTTCGAACCCAAGCTGATCCGCACTGTGC
GCGGGATGGGTTACGTGCTGGAGGCGCCGGGGGCGGCATGA

Upstream 100 bases:

>100_bases
TCGCCAGGCTGACCGGCCGATTACATCTTCGTAATCTTGATCGTGCGGCCGATGGAGGCAGGCACAATGTGGCCGCAACG
CGAATTCCGAGGGAAGCACC

Downstream 100 bases:

>100_bases
GCGCGCGCGCACCGCTTTCGCTCACCGCGCGGCTGGCGCTGCTGTTCGCCGCGCTCGCCGCCAGCCTGCTGATCGTCGTC
GGCCTGGTGATGGGGCGCGC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILIVEDEPKTGDYLRQGLAEAGFVVDLARDGLDGLHLALGGDYDLVVLDVMLPSLDGWGVLQTVRRAGHEMPVLFLTA
RDQVEDRVRGLELGADDYLVKPFAFSELLARVRTLLRRGKAKEAEVLRAADLELDLLRRRVVRGGQRIDLTAKEFALLEL
LLRRQGEVLPRSLIASQVWDMNFDSDTNVIEVAVRRLRAKVDDSFEPKLIRTVRGMGYVLEAPGAA

Sequences:

>Translated_226_residues
MKILIVEDEPKTGDYLRQGLAEAGFVVDLARDGLDGLHLALGGDYDLVVLDVMLPSLDGWGVLQTVRRAGHEMPVLFLTA
RDQVEDRVRGLELGADDYLVKPFAFSELLARVRTLLRRGKAKEAEVLRAADLELDLLRRRVVRGGQRIDLTAKEFALLEL
LLRRQGEVLPRSLIASQVWDMNFDSDTNVIEVAVRRLRAKVDDSFEPKLIRTVRGMGYVLEAPGAA
>Mature_226_residues
MKILIVEDEPKTGDYLRQGLAEAGFVVDLARDGLDGLHLALGGDYDLVVLDVMLPSLDGWGVLQTVRRAGHEMPVLFLTA
RDQVEDRVRGLELGADDYLVKPFAFSELLARVRTLLRRGKAKEAEVLRAADLELDLLRRRVVRGGQRIDLTAKEFALLEL
LLRRQGEVLPRSLIASQVWDMNFDSDTNVIEVAVRRLRAKVDDSFEPKLIRTVRGMGYVLEAPGAA

Specific function: Member of the two-component regulatory system irlR/irlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=68.3035714285714, Blast_Score=312, Evalue=1e-86,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=57.2072072072072, Blast_Score=253, Evalue=8e-69,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=43.1818181818182, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=42.4778761061947, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.579185520362, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=38.2882882882883, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.5454545454545, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.4827586206897, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=36.283185840708, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=36.3636363636364, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.280701754386, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.3964757709251, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.4410480349345, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=29.2372881355932, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=37.3831775700935, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=36.6336633663366, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25259; Mature: 25259

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVEDEPKTGDYLRQGLAEAGFVVDLARDGLDGLHLALGGDYDLVVLDVMLPSLDGW
CEEEEECCCCCCHHHHHHHHHHCCCEEEHHHCCCCCEEEEECCCCCEEEEEHHHCCCCCC
GVLQTVRRAGHEMPVLFLTARDQVEDRVRGLELGADDYLVKPFAFSELLARVRTLLRRGK
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCC
AKEAEVLRAADLELDLLRRRVVRGGQRIDLTAKEFALLELLLRRQGEVLPRSLIASQVWD
CHHHHHHHHHCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
MNFDSDTNVIEVAVRRLRAKVDDSFEPKLIRTVRGMGYVLEAPGAA
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MKILIVEDEPKTGDYLRQGLAEAGFVVDLARDGLDGLHLALGGDYDLVVLDVMLPSLDGW
CEEEEECCCCCCHHHHHHHHHHCCCEEEHHHCCCCCEEEEECCCCCEEEEEHHHCCCCCC
GVLQTVRRAGHEMPVLFLTARDQVEDRVRGLELGADDYLVKPFAFSELLARVRTLLRRGK
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCC
AKEAEVLRAADLELDLLRRRVVRGGQRIDLTAKEFALLELLLRRQGEVLPRSLIASQVWD
CHHHHHHHHHCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
MNFDSDTNVIEVAVRRLRAKVDDSFEPKLIRTVRGMGYVLEAPGAA
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9393784 [H]