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The map label for this gene is acoR [H]

Identifier: 119899136

GI number: 119899136

Start: 3126355

End: 3128244

Strand: Direct

Name: acoR [H]

Synonym: azo2846

Alternate gene names: 119899136

Gene position: 3126355-3128244 (Clockwise)

Preceding gene: 119899133

Following gene: 119899137

Centisome position: 71.44

GC content: 71.75

Gene sequence:

>1890_bases
ATGTCCCGCCCCGAGACCGACTTCGACCACAGGGTGCAGCACGCCCGCCGCCTGATGCAGGAAGGGCGCGAGATTCCCCC
CCAACTGCTCGCCGACCGCGTGCGCCGCTCGTGGTCGCGCTCACGCGAGTACGGCGTGAGCGAGAGCGCGCGCGTCGTCT
TCGATCCGCTCGGCAGGAGCGCGCTGCGCCGTCTCGCGGACGAACACCGCGCGCTGCTGGCCCACGCCGAGCCGGAGATG
CTGAGCCTGTTCGGTACACTCGACGCGTCGAGCTGGGTCGTCGCCTGCCTGGAAGCCGGTGGCGCGGTGCTCAAGTCCTG
CGGCGGCAACACGGCCGAGCTGGGCGACATCGCCACCGCGCTGCGTCCGGGGGTGAACCTCAGCGAACAGGTCGCCGGCA
CCAACGGCCCGGGCTGCGTGCTCGCCGAACAGCGCCCGGCGATCATCCACGGCGGCGAGCACTTTCTCGAAGAGATCCGC
GGCTTCACCTGCGTCGCGGTGCCGATCTTCCATCCCTCCGGCCGCTTGATCGGCGCGCTCAATGCCTCGCGCCGGCACGA
CGGTCGCCGCGCCGGCATCCTCGAACCCCTCGCGCTGGCGGCACGGGCGATCGAAAACCGCTTGCTGTCCGAGCTTGCGG
CACCGATCAGGATGCGCGTGCATAGCACGCCGGAACTGGTGGACTCGGTGATGGCGGGCCGGCTGGCGTGCTCTGCCGAC
GGCCTCATCCTCGGCGCCAGCTCCTGCGCCCGCCAGTTGCTCGGACTGGAGCAGGACGGCGGCGAGATTCCGGCTGCGGC
GGTGTTCTCCACCTCCTTCGGCGAGCTGGTCGGCCTGTTGCGCCGTGGCGCGGACGGGCCGGTGACGGTCCGCTGCAACA
ACGGCGTGCAGGTCCATCTCCGCCTCGACGCCGAAGCGAGACCGCGGCCCGCGCGGCGCATCGGCACTGAGGCCACGCGC
GGCGATCAGGACGCCGCCCGGATGCGCCTCGACAGCCGGCTGCAGAAGGACGTACGCCAGGCCGAGCGCGCCTTCGCCCA
CGACCTGCCGGTGCTGATCAACGGTGAAACCGGCACCGGCAAGGAAGTCCTCGCGCGCCATCTGCACGCCAGTGGCCCGC
GCCGCGACGGCGCCTTCGTTGCGGTCAATTGCTCCGCGATCCCGGTCGGTCTGATCGAATCGGAACTCTTCGGCTACGAG
GACGGCGCCTTCACCGGCGCGCGCCGCGGCGGCATGGCCGGCAAGCTGGAGCAGGCCGATGGCGGCACGCTGTTCCTCGA
CGAGATCGGCGACATGCCGCTGGAACTGCAGGCCCGGCTGCTGCGCGTGCTGCAGGAGCGCACGGTCACGCGGCTGGGCA
GCACCCGCGCCCGCGCCTTCGACTGCTCGCTGATCTGCGCCACCCACCGCGATCTTTCCGCGCACTGCGCCAGCGGCGGA
TTCCGCGAGGACCTCTATTACCGCATCGCCGGCCTGCGGGTGGATCTGCCGCCGCTACGCGAGCGCGAGGACTTCGACGA
ACTGGTGGATCACCTGCTCGCCACCCACGCGCGTGGCGCCCCGCCCCGTCTGGCCGAGCGCGCCCGCGAAGCCCTGCGGC
GCCACCGCTGGCCGGGCAACATTCGCGAACTGCAGCAGGTGCTCCGCCTCGGGATCGCACTGGCCGAACACGGCCGCATC
GACCTCGACCAGCTACCGGCCAGCCTGGCGACTCAAGCCCCGCCTAAACGGACGCCGGGCACCGCTACCACGCTGCAGAG
CGCCGAATGCGACGCGGTGCAGGCGGCCTACGCGCGCAATCGCGGCAACGTCTCCGCCACCGCGCGCGAACTCGGCATTG
CCCGCGCCACGCTGTACCGCAAGCTGCGCCGTTACGGCTGCGCGGACTGA

Upstream 100 bases:

>100_bases
CGCGGCAGGCTGTCAGTGCTCGCTGGCGCAACACTGGATCGATCCGGGCCGGATTCGCCACCGAACTGGATCGATATGAG
TCAACCGTGCAGGAGGAGAC

Downstream 100 bases:

>100_bases
CAACCGGCTAGCCGGGGCGTGGGCGCACGAGGCGGCCTCCGCAACGTGCGCCCACGCCCCGGGCACCGGCCCTTTGCCGC
ATAATCCGGGCCGAGGAGGA

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MSRPETDFDHRVQHARRLMQEGREIPPQLLADRVRRSWSRSREYGVSESARVVFDPLGRSALRRLADEHRALLAHAEPEM
LSLFGTLDASSWVVACLEAGGAVLKSCGGNTAELGDIATALRPGVNLSEQVAGTNGPGCVLAEQRPAIIHGGEHFLEEIR
GFTCVAVPIFHPSGRLIGALNASRRHDGRRAGILEPLALAARAIENRLLSELAAPIRMRVHSTPELVDSVMAGRLACSAD
GLILGASSCARQLLGLEQDGGEIPAAAVFSTSFGELVGLLRRGADGPVTVRCNNGVQVHLRLDAEARPRPARRIGTEATR
GDQDAARMRLDSRLQKDVRQAERAFAHDLPVLINGETGTGKEVLARHLHASGPRRDGAFVAVNCSAIPVGLIESELFGYE
DGAFTGARRGGMAGKLEQADGGTLFLDEIGDMPLELQARLLRVLQERTVTRLGSTRARAFDCSLICATHRDLSAHCASGG
FREDLYYRIAGLRVDLPPLREREDFDELVDHLLATHARGAPPRLAERAREALRRHRWPGNIRELQQVLRLGIALAEHGRI
DLDQLPASLATQAPPKRTPGTATTLQSAECDAVQAAYARNRGNVSATARELGIARATLYRKLRRYGCAD

Sequences:

>Translated_629_residues
MSRPETDFDHRVQHARRLMQEGREIPPQLLADRVRRSWSRSREYGVSESARVVFDPLGRSALRRLADEHRALLAHAEPEM
LSLFGTLDASSWVVACLEAGGAVLKSCGGNTAELGDIATALRPGVNLSEQVAGTNGPGCVLAEQRPAIIHGGEHFLEEIR
GFTCVAVPIFHPSGRLIGALNASRRHDGRRAGILEPLALAARAIENRLLSELAAPIRMRVHSTPELVDSVMAGRLACSAD
GLILGASSCARQLLGLEQDGGEIPAAAVFSTSFGELVGLLRRGADGPVTVRCNNGVQVHLRLDAEARPRPARRIGTEATR
GDQDAARMRLDSRLQKDVRQAERAFAHDLPVLINGETGTGKEVLARHLHASGPRRDGAFVAVNCSAIPVGLIESELFGYE
DGAFTGARRGGMAGKLEQADGGTLFLDEIGDMPLELQARLLRVLQERTVTRLGSTRARAFDCSLICATHRDLSAHCASGG
FREDLYYRIAGLRVDLPPLREREDFDELVDHLLATHARGAPPRLAERAREALRRHRWPGNIRELQQVLRLGIALAEHGRI
DLDQLPASLATQAPPKRTPGTATTLQSAECDAVQAAYARNRGNVSATARELGIARATLYRKLRRYGCAD
>Mature_628_residues
SRPETDFDHRVQHARRLMQEGREIPPQLLADRVRRSWSRSREYGVSESARVVFDPLGRSALRRLADEHRALLAHAEPEML
SLFGTLDASSWVVACLEAGGAVLKSCGGNTAELGDIATALRPGVNLSEQVAGTNGPGCVLAEQRPAIIHGGEHFLEEIRG
FTCVAVPIFHPSGRLIGALNASRRHDGRRAGILEPLALAARAIENRLLSELAAPIRMRVHSTPELVDSVMAGRLACSADG
LILGASSCARQLLGLEQDGGEIPAAAVFSTSFGELVGLLRRGADGPVTVRCNNGVQVHLRLDAEARPRPARRIGTEATRG
DQDAARMRLDSRLQKDVRQAERAFAHDLPVLINGETGTGKEVLARHLHASGPRRDGAFVAVNCSAIPVGLIESELFGYED
GAFTGARRGGMAGKLEQADGGTLFLDEIGDMPLELQARLLRVLQERTVTRLGSTRARAFDCSLICATHRDLSAHCASGGF
REDLYYRIAGLRVDLPPLREREDFDELVDHLLATHARGAPPRLAERAREALRRHRWPGNIRELQQVLRLGIALAEHGRID
LDQLPASLATQAPPKRTPGTATTLQSAECDAVQAAYARNRGNVSATARELGIARATLYRKLRRYGCAD

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=310, Percent_Identity=41.6129032258065, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1790437, Length=278, Percent_Identity=43.8848920863309, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1790299, Length=308, Percent_Identity=41.5584415584416, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788905, Length=292, Percent_Identity=41.7808219178082, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1788550, Length=291, Percent_Identity=40.5498281786942, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786524, Length=300, Percent_Identity=44.3333333333333, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI87082117, Length=310, Percent_Identity=41.2903225806452, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=41.3333333333333, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87082152, Length=315, Percent_Identity=38.0952380952381, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI87081872, Length=244, Percent_Identity=42.6229508196721, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=33.4415584415584, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1789828, Length=226, Percent_Identity=42.0353982300885, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081858, Length=541, Percent_Identity=26.9870609981516, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68245; Mature: 68113

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPETDFDHRVQHARRLMQEGREIPPQLLADRVRRSWSRSREYGVSESARVVFDPLGRS
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
ALRRLADEHRALLAHAEPEMLSLFGTLDASSWVVACLEAGGAVLKSCGGNTAELGDIATA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHH
LRPGVNLSEQVAGTNGPGCVLAEQRPAIIHGGEHFLEEIRGFTCVAVPIFHPSGRLIGAL
HCCCCCCHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHCCCEEEEEEEECCCCCEEECC
NASRRHDGRRAGILEPLALAARAIENRLLSELAAPIRMRVHSTPELVDSVMAGRLACSAD
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
GLILGASSCARQLLGLEQDGGEIPAAAVFSTSFGELVGLLRRGADGPVTVRCNNGVQVHL
CEEEEHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCEEEEE
RLDAEARPRPARRIGTEATRGDQDAARMRLDSRLQKDVRQAERAFAHDLPVLINGETGTG
EECCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KEVLARHLHASGPRRDGAFVAVNCSAIPVGLIESELFGYEDGAFTGARRGGMAGKLEQAD
HHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GGTLFLDEIGDMPLELQARLLRVLQERTVTRLGSTRARAFDCSLICATHRDLSAHCASGG
CCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHCCCC
FREDLYYRIAGLRVDLPPLREREDFDELVDHLLATHARGAPPRLAERAREALRRHRWPGN
HHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
IRELQQVLRLGIALAEHGRIDLDQLPASLATQAPPKRTPGTATTLQSAECDAVQAAYARN
HHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHC
RGNVSATARELGIARATLYRKLRRYGCAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRPETDFDHRVQHARRLMQEGREIPPQLLADRVRRSWSRSREYGVSESARVVFDPLGRS
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
ALRRLADEHRALLAHAEPEMLSLFGTLDASSWVVACLEAGGAVLKSCGGNTAELGDIATA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHH
LRPGVNLSEQVAGTNGPGCVLAEQRPAIIHGGEHFLEEIRGFTCVAVPIFHPSGRLIGAL
HCCCCCCHHHHCCCCCCCEEEECCCCCEEECCHHHHHHHCCCEEEEEEEECCCCCEEECC
NASRRHDGRRAGILEPLALAARAIENRLLSELAAPIRMRVHSTPELVDSVMAGRLACSAD
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
GLILGASSCARQLLGLEQDGGEIPAAAVFSTSFGELVGLLRRGADGPVTVRCNNGVQVHL
CEEEEHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCEEEEE
RLDAEARPRPARRIGTEATRGDQDAARMRLDSRLQKDVRQAERAFAHDLPVLINGETGTG
EECCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KEVLARHLHASGPRRDGAFVAVNCSAIPVGLIESELFGYEDGAFTGARRGGMAGKLEQAD
HHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GGTLFLDEIGDMPLELQARLLRVLQERTVTRLGSTRARAFDCSLICATHRDLSAHCASGG
CCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHCCCC
FREDLYYRIAGLRVDLPPLREREDFDELVDHLLATHARGAPPRLAERAREALRRHRWPGN
HHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
IRELQQVLRLGIALAEHGRIDLDQLPASLATQAPPKRTPGTATTLQSAECDAVQAAYARN
HHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHHHC
RGNVSATARELGIARATLYRKLRRYGCAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]