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The map label for this gene is pgk

Identifier: 119899129

GI number: 119899129

Start: 3118003

End: 3119187

Strand: Direct

Name: pgk

Synonym: azo2839

Alternate gene names: 119899129

Gene position: 3118003-3119187 (Clockwise)

Preceding gene: 119899128

Following gene: 119899132

Centisome position: 71.25

GC content: 67.34

Gene sequence:

>1185_bases
ATGCAAGTCAAGAAACTCACCGACCTCGACGTCCGTGGCAAGAAGGTCTTCATCCGCGCCGACCTCAACGTGCCGCAGGA
CGAAGCCGGCAACATCACCGAAGACACCCGCATCCGCGCCTCCATCCCGTCCATCCAGTACTGCCTGGACAACGGCGCCG
CGGTGATGGTCACCTCCCACCTCGGCCGTCCGACCGAAGGCGAAGTCGGCCCCGACGACACCCTGGCGCCGGTCGCCGTG
CGCCTCGGCCAGCTGCTGCACAAGCCGGTCAAGCTGATCGCCAACTGGGTCGAGGGTGGTTTTGAAGTCAAGCCGGGCGA
AGTCGTCCTGCTGGAAAACTGCCGCTGCAACAAGGGCGAGAAGAAGGACAACGAAGAGCTGGCGAAGAAGATGGCGGCGC
TGTGCGACGTCTATGTCAACGACGCCTTCGGCACCGCCCACCGCGCCGAGGCCACCACCCACGGCATCGCCCGCTTCGCC
CCGGTGTCCTGCGCCGGCATCCTGATGGGGGCCGAGATCGACGCGCTGTCGAAGGCGCTGCACCAGCCGGCCCGCCCGCT
GGTGGCCATCGTCGGCGGCGCCAAGGTGTCGACCAAGCTGACCATCCTCAAGACGCTGGCCGACAAGGTCGACCAGCTCA
TCGTCGGCGGCGGCATCGCCAACACCTTCCTGCTGGCAGCCGGCAAGCGCATCGGCGAATCGCTGGCCGAGCCGGAAATG
GTGCGTGAAGCCCAGCAGGTGATGGACATCATGAAGTCGCGCGGCGCCGAAGTGCCGCTGCCGATCGACGTCGTGGTGGC
GGACGAGGTGTCGGCCCTGGCGCGCGCCAACCGGATTTCCGTGGATGAAGTCGGCCCGCACGACCGCATCCTCGACTTCG
GCCCCAAGACCTCGGCCAAGCTCGCCGACATCATCGCGCACGCCGGCACCATCGTCTGGAACGGTCCGGTCGGCGTGTTC
GAGCACGCCCAGTTCGCCGGTGGCACCAAGATGATGGCCTCGGCCATCGCGCACTCCGAGGCGTTCTCCATCGCCGGTGG
CGGCGACACCCTGGCCGCGATCGCGAAGTTCCACATCGCTGACGACGTGGGCTACATCTCGACCGGCGGCGGCGCCTTCC
TCGAGTTCCTGGAAGGCAAGAAGCTGCCCGCCATCGCCGCGCTGGAAGCGCGCTACGAGGGCTGA

Upstream 100 bases:

>100_bases
GACGCCAGCGAAGACGGTTACCAGTAACAGCGCAACCACGAGCCGGGTTCCGGGCACCGCCTGAACCCGGCTCTTCTTAC
ATCCGGATCCGATCACGTCC

Downstream 100 bases:

>100_bases
GCGGTTTCGCGCTTCACAGCAAAGCGGCGGCCCACGGGCCGCCGTTTGTTTTTGCCGCGATCGGCACCGGGTTGCAGATC
AGCCGCGCTGGCTGACCGCG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQVKKLTDLDVRGKKVFIRADLNVPQDEAGNITEDTRIRASIPSIQYCLDNGAAVMVTSHLGRPTEGEVGPDDTLAPVAV
RLGQLLHKPVKLIANWVEGGFEVKPGEVVLLENCRCNKGEKKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFA
PVSCAGILMGAEIDALSKALHQPARPLVAIVGGAKVSTKLTILKTLADKVDQLIVGGGIANTFLLAAGKRIGESLAEPEM
VREAQQVMDIMKSRGAEVPLPIDVVVADEVSALARANRISVDEVGPHDRILDFGPKTSAKLADIIAHAGTIVWNGPVGVF
EHAQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIADDVGYISTGGGAFLEFLEGKKLPAIAALEARYEG

Sequences:

>Translated_394_residues
MQVKKLTDLDVRGKKVFIRADLNVPQDEAGNITEDTRIRASIPSIQYCLDNGAAVMVTSHLGRPTEGEVGPDDTLAPVAV
RLGQLLHKPVKLIANWVEGGFEVKPGEVVLLENCRCNKGEKKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFA
PVSCAGILMGAEIDALSKALHQPARPLVAIVGGAKVSTKLTILKTLADKVDQLIVGGGIANTFLLAAGKRIGESLAEPEM
VREAQQVMDIMKSRGAEVPLPIDVVVADEVSALARANRISVDEVGPHDRILDFGPKTSAKLADIIAHAGTIVWNGPVGVF
EHAQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIADDVGYISTGGGAFLEFLEGKKLPAIAALEARYEG
>Mature_394_residues
MQVKKLTDLDVRGKKVFIRADLNVPQDEAGNITEDTRIRASIPSIQYCLDNGAAVMVTSHLGRPTEGEVGPDDTLAPVAV
RLGQLLHKPVKLIANWVEGGFEVKPGEVVLLENCRCNKGEKKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFA
PVSCAGILMGAEIDALSKALHQPARPLVAIVGGAKVSTKLTILKTLADKVDQLIVGGGIANTFLLAAGKRIGESLAEPEM
VREAQQVMDIMKSRGAEVPLPIDVVVADEVSALARANRISVDEVGPHDRILDFGPKTSAKLADIIAHAGTIVWNGPVGVF
EHAQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIADDVGYISTGGGAFLEFLEGKKLPAIAALEARYEG

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI31543397, Length=416, Percent_Identity=43.2692307692308, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI4505763, Length=412, Percent_Identity=41.9902912621359, Blast_Score=277, Evalue=1e-74,
Organism=Escherichia coli, GI1789294, Length=391, Percent_Identity=59.3350383631714, Blast_Score=447, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17508823, Length=411, Percent_Identity=42.3357664233577, Blast_Score=282, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6319857, Length=411, Percent_Identity=41.1192214111922, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI17136394, Length=420, Percent_Identity=40.4761904761905, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24581203, Length=416, Percent_Identity=38.9423076923077, Blast_Score=247, Evalue=1e-65,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_AZOSB (A1K9F0)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934342.1
- ProteinModelPortal:   A1K9F0
- SMR:   A1K9F0
- STRING:   A1K9F0
- GeneID:   4607640
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2839
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   DCIGDEV
- PhylomeDB:   A1K9F0
- ProtClustDB:   PRK00073
- BioCyc:   ASP62928:AZO2839-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 41548; Mature: 41548

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 37-37 BINDING 115-115 BINDING 148-148 BINDING 199-199 BINDING 321-321

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKKLTDLDVRGKKVFIRADLNVPQDEAGNITEDTRIRASIPSIQYCLDNGAAVMVTSH
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCEEEEEEC
LGRPTEGEVGPDDTLAPVAVRLGQLLHKPVKLIANWVEGGFEVKPGEVVLLENCRCNKGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCC
KKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFAPVSCAGILMGAEIDALSKAL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHH
HQPARPLVAIVGGAKVSTKLTILKTLADKVDQLIVGGGIANTFLLAAGKRIGESLAEPEM
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCHHH
VREAQQVMDIMKSRGAEVPLPIDVVVADEVSALARANRISVDEVGPHDRILDFGPKTSAK
HHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHH
LADIIAHAGTIVWNGPVGVFEHAQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIA
HHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
DDVGYISTGGGAFLEFLEGKKLPAIAALEARYEG
CCCCEEECCHHHHHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MQVKKLTDLDVRGKKVFIRADLNVPQDEAGNITEDTRIRASIPSIQYCLDNGAAVMVTSH
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCEEEEEEC
LGRPTEGEVGPDDTLAPVAVRLGQLLHKPVKLIANWVEGGFEVKPGEVVLLENCRCNKGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCC
KKDNEELAKKMAALCDVYVNDAFGTAHRAEATTHGIARFAPVSCAGILMGAEIDALSKAL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHH
HQPARPLVAIVGGAKVSTKLTILKTLADKVDQLIVGGGIANTFLLAAGKRIGESLAEPEM
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCHHH
VREAQQVMDIMKSRGAEVPLPIDVVVADEVSALARANRISVDEVGPHDRILDFGPKTSAK
HHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHH
LADIIAHAGTIVWNGPVGVFEHAQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIA
HHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
DDVGYISTGGGAFLEFLEGKKLPAIAALEARYEG
CCCCEEECCHHHHHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA