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The map label for this gene is gapA [H]

Identifier: 119899127

GI number: 119899127

Start: 3116428

End: 3117444

Strand: Direct

Name: gapA [H]

Synonym: azo2837

Alternate gene names: 119899127

Gene position: 3116428-3117444 (Clockwise)

Preceding gene: 119899126

Following gene: 119899128

Centisome position: 71.22

GC content: 64.5

Gene sequence:

>1017_bases
ATGACCATCAAAATCGCCATCAACGGTTACGGCCGCATCGGCCGCTGCACGCTGCGCGCCCTCTACGAACTCGGCCTGCG
CGACCAGTTCGAAGTCGTGGCGATCAACGCCTCCGGCGACCTGGCCACCAACGCCCACCTGACCAAGTACGACACCACCC
ACGGCCGCTTCGCCTTCCCGGTGGAAACCGAAGGCGACAACGTGATGATCGTCAATGGCGACCGCATCCCGTTCTTCTCC
ACCAAGGATCCGCTGGCGATCAACTGGGGCGACCTCGGCGTGGACGTGCTGCTCGAATGCACCGGCGCCTACACCGCCAA
GGCCAAGGCCGAAGTGCACCTCAAGCAGGGCGCCAAGAAGATCCTGATCTCCGCCCCGGGTGGCGACGATGTGGATGCCA
CCATCGTCTATGGTGTGAACCACGACGTGCTGACCGCCGCGATGACCGTGGTCTCCAACGCCTCGTGCACCACCAACTGC
CTGGCCCCGGTCGCCAAGGTGCTGCAGGACAACATCGGCATCGAAAAGGGCCTGATGACCACCATCCACGCCTACACCAA
CGACCAGGTGCTGGTGGATGTGCGCCACAAGGACCTGCGCCGCGCCCGTGCCGCCGCGCAGAACATCATCCCCACCAAAA
CCGGCGCCGCCAAGGCCGTCGGCCTGGTGCTGCCGGCGCTCAAGGGCAAGTTCGACGGTTTCGCGCTGCGCGTGCCGACC
ATGAACGTGTCGCTGGTCGACCTCACCTTCACCGCCAGCCGCGCCACCAGCAAGGAAGAGATCAACAGCCTGATGATCGA
AGCCTCCAAGGGCGCGCTCAAGGGCGTGCTCGCGGTAAACGAGGCGCCGCTGGTGTCGATGGACTTCAACCACGACCCGC
ACTCCTCGGTGTTCGATGCCACCCAGACCCGCGTCATGGACGGCAATCTGGTCAAGGTTCTCGCCTGGTACGACAATGAG
TGGGGCTATTCCTGCCGCATGCTCGACGCGGCCAAGGCGCTGGCCCAGGCCAAGTAA

Upstream 100 bases:

>100_bases
TAATTCGCACGGCGATGGCAGGGACCCGATCAGACGCCCCGCCATCGCGCCGCCAACCAGTTCTGATGCCTGTGTTGCCC
ACGCTCCTGGAGACTCCTCG

Downstream 100 bases:

>100_bases
CCCACCGAGGACCCACGATGAACCGTCTCCTGATCGCCCTGCTCGCCACCGGCGCCCTGTTCGCCGCGGGCTGCACCTCC
AACCAGAGCCGCCCCGCCGC

Product: putative glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTIKIAINGYGRIGRCTLRALYELGLRDQFEVVAINASGDLATNAHLTKYDTTHGRFAFPVETEGDNVMIVNGDRIPFFS
TKDPLAINWGDLGVDVLLECTGAYTAKAKAEVHLKQGAKKILISAPGGDDVDATIVYGVNHDVLTAAMTVVSNASCTTNC
LAPVAKVLQDNIGIEKGLMTTIHAYTNDQVLVDVRHKDLRRARAAAQNIIPTKTGAAKAVGLVLPALKGKFDGFALRVPT
MNVSLVDLTFTASRATSKEEINSLMIEASKGALKGVLAVNEAPLVSMDFNHDPHSSVFDATQTRVMDGNLVKVLAWYDNE
WGYSCRMLDAAKALAQAK

Sequences:

>Translated_338_residues
MTIKIAINGYGRIGRCTLRALYELGLRDQFEVVAINASGDLATNAHLTKYDTTHGRFAFPVETEGDNVMIVNGDRIPFFS
TKDPLAINWGDLGVDVLLECTGAYTAKAKAEVHLKQGAKKILISAPGGDDVDATIVYGVNHDVLTAAMTVVSNASCTTNC
LAPVAKVLQDNIGIEKGLMTTIHAYTNDQVLVDVRHKDLRRARAAAQNIIPTKTGAAKAVGLVLPALKGKFDGFALRVPT
MNVSLVDLTFTASRATSKEEINSLMIEASKGALKGVLAVNEAPLVSMDFNHDPHSSVFDATQTRVMDGNLVKVLAWYDNE
WGYSCRMLDAAKALAQAK
>Mature_337_residues
TIKIAINGYGRIGRCTLRALYELGLRDQFEVVAINASGDLATNAHLTKYDTTHGRFAFPVETEGDNVMIVNGDRIPFFST
KDPLAINWGDLGVDVLLECTGAYTAKAKAEVHLKQGAKKILISAPGGDDVDATIVYGVNHDVLTAAMTVVSNASCTTNCL
APVAKVLQDNIGIEKGLMTTIHAYTNDQVLVDVRHKDLRRARAAAQNIIPTKTGAAKAVGLVLPALKGKFDGFALRVPTM
NVSLVDLTFTASRATSKEEINSLMIEASKGALKGVLAVNEAPLVSMDFNHDPHSSVFDATQTRVMDGNLVKVLAWYDNEW
GYSCRMLDAAKALAQAK

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=46.1538461538462, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=44.8484848484849, Blast_Score=265, Evalue=5e-71,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=50.4477611940299, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=49.3939393939394, Blast_Score=299, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=49.5495495495495, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=48.948948948949, Blast_Score=293, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=46.4497041420118, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=46.9879518072289, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=46.3126843657817, Blast_Score=293, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=46.0176991150442, Blast_Score=291, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=46.3126843657817, Blast_Score=290, Evalue=2e-79,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=51.0385756676558, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=51.0385756676558, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=50.7418397626113, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=50.7418397626113, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=45.8715596330275, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36321; Mature: 36190

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIAINGYGRIGRCTLRALYELGLRDQFEVVAINASGDLATNAHLTKYDTTHGRFAFP
CEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEE
VETEGDNVMIVNGDRIPFFSTKDPLAINWGDLGVDVLLECTGAYTAKAKAEVHLKQGAKK
EECCCCEEEEEECCCCCEECCCCCCEEECCCCCEEEEEEECCCEEECCEEEEEECCCCEE
ILISAPGGDDVDATIVYGVNHDVLTAAMTVVSNASCTTNCLAPVAKVLQDNIGIEKGLMT
EEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEE
TIHAYTNDQVLVDVRHKDLRRARAAAQNIIPTKTGAAKAVGLVLPALKGKFDGFALRVPT
EEEEECCCEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECC
MNVSLVDLTFTASRATSKEEINSLMIEASKGALKGVLAVNEAPLVSMDFNHDPHSSVFDA
CEEEEEEEEEECCCCCCHHHHHHEEEECCCCCEEEEEEECCCCEEEEECCCCCCCHHHHC
TQTRVMDGNLVKVLAWYDNEWGYSCRMLDAAKALAQAK
HHEEEECCCEEEEEEEECCCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure 
TIKIAINGYGRIGRCTLRALYELGLRDQFEVVAINASGDLATNAHLTKYDTTHGRFAFP
EEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEE
VETEGDNVMIVNGDRIPFFSTKDPLAINWGDLGVDVLLECTGAYTAKAKAEVHLKQGAKK
EECCCCEEEEEECCCCCEECCCCCCEEECCCCCEEEEEEECCCEEECCEEEEEECCCCEE
ILISAPGGDDVDATIVYGVNHDVLTAAMTVVSNASCTTNCLAPVAKVLQDNIGIEKGLMT
EEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEE
TIHAYTNDQVLVDVRHKDLRRARAAAQNIIPTKTGAAKAVGLVLPALKGKFDGFALRVPT
EEEEECCCEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECC
MNVSLVDLTFTASRATSKEEINSLMIEASKGALKGVLAVNEAPLVSMDFNHDPHSSVFDA
CEEEEEEEEEECCCCCCHHHHHHEEEECCCCCEEEEEEECCCCEEEEECCCCCCCHHHHC
TQTRVMDGNLVKVLAWYDNEWGYSCRMLDAAKALAQAK
HHEEEECCCEEEEEEEECCCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]