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The map label for this gene is argA [H]

Identifier: 119899120

GI number: 119899120

Start: 3108245

End: 3109603

Strand: Reverse

Name: argA [H]

Synonym: azo2830

Alternate gene names: 119899120

Gene position: 3109603-3108245 (Counterclockwise)

Preceding gene: 119899121

Following gene: 119899119

Centisome position: 71.06

GC content: 67.11

Gene sequence:

>1359_bases
TTGAACGCCGAATCCCCAACCGCCCAGGCTGCACTTCCCGTTGCTGCAGACTCCACCGCTCAGTTCGTTGCCTGGGTGCG
GGGTGCTGCGCCCTACATCCACGCTTTTCGCGGCAAGACCTTCGTGGTGGCGTTTGGCGGCGAGGTGGCGGGCGGTGAGC
GGGCGCAAAGCCTCGCCTACGATTGCAACCTGCTGGCGGCGCTCGGAATCCGCCTGGTGCTGGTTCACGGTGCGCGTCCG
CAGATCGACGCCGAAGTCGCCCGGCGCGGACTGGAACCGCGCTTTCACAACGGCCTGAGGGTCACGGATGCCGCGGCGCT
TGAGTGCGTCAAGGCGGCGATGGCAGTTACCCGGTTCGAGGTCGAGGCACTGTTGTCCCAGGGCTTGCCGAATACGCCGA
TGGCCGGCAGCTACATGCGGGTCACGGGCGGCAACTTCATCACCGCGCGGCCGTTCGGCGTGGTCGATGGCGTCGACTTC
CAATACACCGGTGCCGTGCGGCGCATCATCGCCGACGAAATCAACGCCGACCTCGACCAGCAGAACGTGGTGCTGATCAC
GCCGCTGGGCGTGTCTCCGGCGGGCGAAATCTTCAATCTCTGCATGGAAGAGGTGGCCGAGGCGGTGGCGGTTGCGCTGA
AGGCCGAAAAGCTGATCTACCTGTGCGATGCGCCGGGCCTGCTCGACCCCGAGGGCAAGCTGGTGGAGTCGGTCACCGCG
GACGAGGCCGCGCGCAAGCTGGAGGCGGGAGAAGGCCTGACCGAGGACCTCCATCTCTATCTGCCGTGCGCGATCCGCGC
CGTCCGCAAGGGCGTGTCGCGCTGCCACCTGATCGACCGCGACAAGGACGGCGGGCTGCTGCTGGAGTTCTTTACCCACG
CGGGCGTCGGCACCGTCGTCTCGCGCGATCCGCTTTTCCGCCTGCGCGAAGCGACCATCGACGACGTCGGTGCGCTGGTG
TCGCTGATCTCGCCGATGGAAGCCGACGGCACCCTGGTACGGCGCGGGCGTGAATTGCTGGAACAGGAAGTCGACCGCTT
CAGCGTCGTCGAGCACGACGGCGTGCTGGTGGGCTGCGCGGCGCTGTACCCGTTCAGCGACGAGAGCGCGGCCGAACTGG
CCTGCCTCGCGGTGATGCCGGAATACCGCCGCGCCGGGTTGGGCGACCAGCTCTTGCGTCGTATCGAACGCCGCGCGCGC
ATGCAGCGGCTGGAACGTCTGTTCGTGCTTACCACGCGCACCGCGCACTGGTTCCGCGAGCGTGGCTTCAGCGAGGTCAG
TCCCGAGGCACTGCCACGGCAAAAGCGCGAGCTGTACAACTTCCAGCGCCGGTCCAAGGTATTCGCCAAGCCGCTATGA

Upstream 100 bases:

>100_bases
AACCCTGCCAAGTGGCAGGGCTTCGGCTAGAATCCGGGAACACTATACCGACGGCCTCCACCGCCTACGCGGCGGCGCCG
CAATCCACACCGGTGCACGA

Downstream 100 bases:

>100_bases
CCCCAGTCGATCTCCATCTCGAGCGGGCGCGGCCCCTGATGGAGGGGGCGGGGGAGTGGCGAGCCGGAGGGGCGCACGAT
GCCTGATTTCGGCGGAACGC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNAESPTAQAALPVAADSTAQFVAWVRGAAPYIHAFRGKTFVVAFGGEVAGGERAQSLAYDCNLLAALGIRLVLVHGARP
QIDAEVARRGLEPRFHNGLRVTDAAALECVKAAMAVTRFEVEALLSQGLPNTPMAGSYMRVTGGNFITARPFGVVDGVDF
QYTGAVRRIIADEINADLDQQNVVLITPLGVSPAGEIFNLCMEEVAEAVAVALKAEKLIYLCDAPGLLDPEGKLVESVTA
DEAARKLEAGEGLTEDLHLYLPCAIRAVRKGVSRCHLIDRDKDGGLLLEFFTHAGVGTVVSRDPLFRLREATIDDVGALV
SLISPMEADGTLVRRGRELLEQEVDRFSVVEHDGVLVGCAALYPFSDESAAELACLAVMPEYRRAGLGDQLLRRIERRAR
MQRLERLFVLTTRTAHWFRERGFSEVSPEALPRQKRELYNFQRRSKVFAKPL

Sequences:

>Translated_452_residues
MNAESPTAQAALPVAADSTAQFVAWVRGAAPYIHAFRGKTFVVAFGGEVAGGERAQSLAYDCNLLAALGIRLVLVHGARP
QIDAEVARRGLEPRFHNGLRVTDAAALECVKAAMAVTRFEVEALLSQGLPNTPMAGSYMRVTGGNFITARPFGVVDGVDF
QYTGAVRRIIADEINADLDQQNVVLITPLGVSPAGEIFNLCMEEVAEAVAVALKAEKLIYLCDAPGLLDPEGKLVESVTA
DEAARKLEAGEGLTEDLHLYLPCAIRAVRKGVSRCHLIDRDKDGGLLLEFFTHAGVGTVVSRDPLFRLREATIDDVGALV
SLISPMEADGTLVRRGRELLEQEVDRFSVVEHDGVLVGCAALYPFSDESAAELACLAVMPEYRRAGLGDQLLRRIERRAR
MQRLERLFVLTTRTAHWFRERGFSEVSPEALPRQKRELYNFQRRSKVFAKPL
>Mature_452_residues
MNAESPTAQAALPVAADSTAQFVAWVRGAAPYIHAFRGKTFVVAFGGEVAGGERAQSLAYDCNLLAALGIRLVLVHGARP
QIDAEVARRGLEPRFHNGLRVTDAAALECVKAAMAVTRFEVEALLSQGLPNTPMAGSYMRVTGGNFITARPFGVVDGVDF
QYTGAVRRIIADEINADLDQQNVVLITPLGVSPAGEIFNLCMEEVAEAVAVALKAEKLIYLCDAPGLLDPEGKLVESVTA
DEAARKLEAGEGLTEDLHLYLPCAIRAVRKGVSRCHLIDRDKDGGLLLEFFTHAGVGTVVSRDPLFRLREATIDDVGALV
SLISPMEADGTLVRRGRELLEQEVDRFSVVEHDGVLVGCAALYPFSDESAAELACLAVMPEYRRAGLGDQLLRRIERRAR
MQRLERLFVLTTRTAHWFRERGFSEVSPEALPRQKRELYNFQRRSKVFAKPL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=436, Percent_Identity=45.6422018348624, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49354; Mature: 49354

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAESPTAQAALPVAADSTAQFVAWVRGAAPYIHAFRGKTFVVAFGGEVAGGERAQSLAY
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
DCNLLAALGIRLVLVHGARPQIDAEVARRGLEPRFHNGLRVTDAAALECVKAAMAVTRFE
HHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCHHCCCCEEHHHHHHHHHHHHHHHHHHH
VEALLSQGLPNTPMAGSYMRVTGGNFITARPFGVVDGVDFQYTGAVRRIIADEINADLDQ
HHHHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
QNVVLITPLGVSPAGEIFNLCMEEVAEAVAVALKAEKLIYLCDAPGLLDPEGKLVESVTA
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHH
DEAARKLEAGEGLTEDLHLYLPCAIRAVRKGVSRCHLIDRDKDGGLLLEFFTHAGVGTVV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHHHCCCCCEE
SRDPLFRLREATIDDVGALVSLISPMEADGTLVRRGRELLEQEVDRFSVVEHDGVLVGCA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEEE
ALYPFSDESAAELACLAVMPEYRRAGLGDQLLRRIERRARMQRLERLFVLTTRTAHWFRE
EECCCCCCCHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFSEVSPEALPRQKRELYNFQRRSKVFAKPL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAESPTAQAALPVAADSTAQFVAWVRGAAPYIHAFRGKTFVVAFGGEVAGGERAQSLAY
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
DCNLLAALGIRLVLVHGARPQIDAEVARRGLEPRFHNGLRVTDAAALECVKAAMAVTRFE
HHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCHHCCCCEEHHHHHHHHHHHHHHHHHHH
VEALLSQGLPNTPMAGSYMRVTGGNFITARPFGVVDGVDFQYTGAVRRIIADEINADLDQ
HHHHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
QNVVLITPLGVSPAGEIFNLCMEEVAEAVAVALKAEKLIYLCDAPGLLDPEGKLVESVTA
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHH
DEAARKLEAGEGLTEDLHLYLPCAIRAVRKGVSRCHLIDRDKDGGLLLEFFTHAGVGTVV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHHHCCCCCEE
SRDPLFRLREATIDDVGALVSLISPMEADGTLVRRGRELLEQEVDRFSVVEHDGVLVGCA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEEE
ALYPFSDESAAELACLAVMPEYRRAGLGDQLLRRIERRARMQRLERLFVLTTRTAHWFRE
EECCCCCCCHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFSEVSPEALPRQKRELYNFQRRSKVFAKPL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]