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The map label for this gene is yegE [H]

Identifier: 119899119

GI number: 119899119

Start: 3106427

End: 3108166

Strand: Reverse

Name: yegE [H]

Synonym: azo2829

Alternate gene names: 119899119

Gene position: 3108166-3106427 (Counterclockwise)

Preceding gene: 119899120

Following gene: 119899118

Centisome position: 71.03

GC content: 67.53

Gene sequence:

>1740_bases
ATGCCTGATTTCGGCGGAACGCCTCGCGCCATTCCCCGCTGGCACGTCCTGATGGCGGCGCTTGGCGGCGCGCTGGTGGT
GGCGCTGGTGATTGTGCTCGCGCCATGGCTTGCAGGTGCAGGATGGGCGCCCGGCGTGGTCGCGGTGGTCGTTGCGGGGG
CGCTTGCCGCGCTCGGAGCGTATTGCCAGCAGCGCCGCATGCTGGGCTTGTTGCGGCGCGACGAGTCCGAACTGCACAGC
CGCATCGACGCTTGGCACGAGGCGGGCAGCCTGCCGGCAAGCGAACTGGCGTGTCCGCTCGAGCGGATTGACCGCGCCGC
CGGCCAGACCCTGTTCCTGCGCCAGATCGCCGAAGGCGTGCATGGCCTGGAGGCACTGTTCGACGACGGCGGACGGCTGC
TGTGGATCAGCCCCTCGATCGAGCGCTTGACCGGGTGGACGCCGCAGGAGTGCGTGGCGGCGAACGACCCGATCGAAACG
CTGGCGCATGAATCGGACCGCCGCTACTGCAAGCGGGCGGCGGAGCAGGTGCTGGCCGACGGCGTCCAGCAGGAGTTCGA
GATGCGCTTGGCGCACAAGGACGGCCGCTACGGCTGGGTCGCGTGCCGCTGGCGCGCGCTGGTGGACGGCAGCGGGCGCC
GCGTGGGCTTGCGGATGTCGGCGGAAGACATCCAGGCCCGCAAGGAAACAGAGTACAAGCTGCTGGAAACCGTGGCCGAA
CTGCGCCGCGCCCAGGCGCTGCGCGAGCACTACCTGGCACGCAGCAACGACGAGCGCCAGCGCCTCGCTGCGCTGCTGAA
CGTCATCGGCCTCGGGATCATCTTCATCGACCATGACCATCGCGTGCTGTACTTCAACCGCGCGATGCTGAAGATCTGGG
GCTTCCCCCCCGATGAAAACCTGATCGGCACACGCGATGTGGTACTGCAGCGGACGATCGCGCCGCTGCTCGCCGATCCC
GAGTCCTATTTCGCCCACATCGAGGAGGTGCTCGCGGACCGCCGGTCGGTCAGCGAGCAGTTCGAGGTCCGCATGAAGGA
CGGGCGCATCGTCACCGACATTTCGTCGGTGGTCGAAAGCGGCAAGGGCGCACGGGGCATCGGCCGGGTCTGGATTTACG
AGGACGTCACCGAGCAGCGCCGGGTGGCCGACCAGCTGATCGCGCTGGCCGAGCGCGATCCGCTGACCAACCTCTATAAC
CGCCGCCGCTTCCATGAAGAACTCGAGCGCATGCTGGCCGAGGCGACCCGGCGCGACCTGGAGGTGGGCTTGGTCGCGAT
CGACCTCGACGGCTTCAAGCCGATCAACGACCGCTTCGGCCACCAGGCGGGCGACGAGGTTCTGGTCGGGGTCGCGGAAG
GGGTCGCCCGCATCATCCGGCGCAACGAAATGTTCTTCCGCCTCGGCGGTGACGAGTTCGCGATGCTGGTGCCCGATACC
TCGGAAGCCGAGCTGTCCGAACTGGCAGCGCGCCTGGTCGAGGCGATCGACGCCCTGCATTTCACATTTGCGGGTGAGTC
GGCGGGTGTGACGGCGAGCATCGGCATCGCGCTGTTCCCGCATCACGGCGAGGGTGGAGAAGCGTTGATGGTGGCCGCGG
ATCAGGCGATGTACCGGTCCAAGAGCGACGGTCGCAACCGCTGGATGGTCTCGGGCGGCAAGCATGGCGGGAACGGGGAA
TCCGATAGAATGGCGGCACGTAATCGCATCCCCGATGAACCCCCCCGTGAAAAGGATTGA

Upstream 100 bases:

>100_bases
GGTATTCGCCAAGCCGCTATGACCCCAGTCGATCTCCATCTCGAGCGGGCGCGGCCCCTGATGGAGGGGGCGGGGGAGTG
GCGAGCCGGAGGGGCGCACG

Downstream 100 bases:

>100_bases
ACGATGGCGCGTATGGTGAACTGCATCAAACTGGGCCGGGAGGCCGAAGGGCTCGACCTTCCGCCCGTGCCCGGCGAACT
GGGCAAGCGGATTTATGAAA

Product: GGDEF/PAS/PAC-domain-containing protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MPDFGGTPRAIPRWHVLMAALGGALVVALVIVLAPWLAGAGWAPGVVAVVVAGALAALGAYCQQRRMLGLLRRDESELHS
RIDAWHEAGSLPASELACPLERIDRAAGQTLFLRQIAEGVHGLEALFDDGGRLLWISPSIERLTGWTPQECVAANDPIET
LAHESDRRYCKRAAEQVLADGVQQEFEMRLAHKDGRYGWVACRWRALVDGSGRRVGLRMSAEDIQARKETEYKLLETVAE
LRRAQALREHYLARSNDERQRLAALLNVIGLGIIFIDHDHRVLYFNRAMLKIWGFPPDENLIGTRDVVLQRTIAPLLADP
ESYFAHIEEVLADRRSVSEQFEVRMKDGRIVTDISSVVESGKGARGIGRVWIYEDVTEQRRVADQLIALAERDPLTNLYN
RRRFHEELERMLAEATRRDLEVGLVAIDLDGFKPINDRFGHQAGDEVLVGVAEGVARIIRRNEMFFRLGGDEFAMLVPDT
SEAELSELAARLVEAIDALHFTFAGESAGVTASIGIALFPHHGEGGEALMVAADQAMYRSKSDGRNRWMVSGGKHGGNGE
SDRMAARNRIPDEPPREKD

Sequences:

>Translated_579_residues
MPDFGGTPRAIPRWHVLMAALGGALVVALVIVLAPWLAGAGWAPGVVAVVVAGALAALGAYCQQRRMLGLLRRDESELHS
RIDAWHEAGSLPASELACPLERIDRAAGQTLFLRQIAEGVHGLEALFDDGGRLLWISPSIERLTGWTPQECVAANDPIET
LAHESDRRYCKRAAEQVLADGVQQEFEMRLAHKDGRYGWVACRWRALVDGSGRRVGLRMSAEDIQARKETEYKLLETVAE
LRRAQALREHYLARSNDERQRLAALLNVIGLGIIFIDHDHRVLYFNRAMLKIWGFPPDENLIGTRDVVLQRTIAPLLADP
ESYFAHIEEVLADRRSVSEQFEVRMKDGRIVTDISSVVESGKGARGIGRVWIYEDVTEQRRVADQLIALAERDPLTNLYN
RRRFHEELERMLAEATRRDLEVGLVAIDLDGFKPINDRFGHQAGDEVLVGVAEGVARIIRRNEMFFRLGGDEFAMLVPDT
SEAELSELAARLVEAIDALHFTFAGESAGVTASIGIALFPHHGEGGEALMVAADQAMYRSKSDGRNRWMVSGGKHGGNGE
SDRMAARNRIPDEPPREKD
>Mature_578_residues
PDFGGTPRAIPRWHVLMAALGGALVVALVIVLAPWLAGAGWAPGVVAVVVAGALAALGAYCQQRRMLGLLRRDESELHSR
IDAWHEAGSLPASELACPLERIDRAAGQTLFLRQIAEGVHGLEALFDDGGRLLWISPSIERLTGWTPQECVAANDPIETL
AHESDRRYCKRAAEQVLADGVQQEFEMRLAHKDGRYGWVACRWRALVDGSGRRVGLRMSAEDIQARKETEYKLLETVAEL
RRAQALREHYLARSNDERQRLAALLNVIGLGIIFIDHDHRVLYFNRAMLKIWGFPPDENLIGTRDVVLQRTIAPLLADPE
SYFAHIEEVLADRRSVSEQFEVRMKDGRIVTDISSVVESGKGARGIGRVWIYEDVTEQRRVADQLIALAERDPLTNLYNR
RRFHEELERMLAEATRRDLEVGLVAIDLDGFKPINDRFGHQAGDEVLVGVAEGVARIIRRNEMFFRLGGDEFAMLVPDTS
EAELSELAARLVEAIDALHFTFAGESAGVTASIGIALFPHHGEGGEALMVAADQAMYRSKSDGRNRWMVSGGKHGGNGES
DRMAARNRIPDEPPREKD

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=385, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787541, Length=196, Percent_Identity=34.1836734693878, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=38.0952380952381, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=37.8205128205128, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787802, Length=191, Percent_Identity=29.8429319371728, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=31.2849162011173, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=35.5029585798817, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=34.1463414634146, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=35.4430379746835, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=32.1428571428571, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=32.9192546583851, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=31.6129032258064, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=35.2564102564103, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 64315; Mature: 64184

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFGGTPRAIPRWHVLMAALGGALVVALVIVLAPWLAGAGWAPGVVAVVVAGALAALGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YCQQRRMLGLLRRDESELHSRIDAWHEAGSLPASELACPLERIDRAAGQTLFLRQIAEGV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHH
HGLEALFDDGGRLLWISPSIERLTGWTPQECVAANDPIETLAHESDRRYCKRAAEQVLAD
HHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHH
GVQQEFEMRLAHKDGRYGWVACRWRALVDGSGRRVGLRMSAEDIQARKETEYKLLETVAE
HHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
LRRAQALREHYLARSNDERQRLAALLNVIGLGIIFIDHDHRVLYFNRAMLKIWGFPPDEN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEECCCEEEEEECEEHEEECCCCCCC
LIGTRDVVLQRTIAPLLADPESYFAHIEEVLADRRSVSEQFEVRMKDGRIVTDISSVVES
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHC
GKGARGIGRVWIYEDVTEQRRVADQLIALAERDPLTNLYNRRRFHEELERMLAEATRRDL
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
EVGLVAIDLDGFKPINDRFGHQAGDEVLVGVAEGVARIIRRNEMFFRLGGDEFAMLVPDT
HEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCC
SEAELSELAARLVEAIDALHFTFAGESAGVTASIGIALFPHHGEGGEALMVAADQAMYRS
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEECCCCCCCCEEEEEEHHHHHHC
KSDGRNRWMVSGGKHGGNGESDRMAARNRIPDEPPREKD
CCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PDFGGTPRAIPRWHVLMAALGGALVVALVIVLAPWLAGAGWAPGVVAVVVAGALAALGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YCQQRRMLGLLRRDESELHSRIDAWHEAGSLPASELACPLERIDRAAGQTLFLRQIAEGV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHH
HGLEALFDDGGRLLWISPSIERLTGWTPQECVAANDPIETLAHESDRRYCKRAAEQVLAD
HHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHH
GVQQEFEMRLAHKDGRYGWVACRWRALVDGSGRRVGLRMSAEDIQARKETEYKLLETVAE
HHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
LRRAQALREHYLARSNDERQRLAALLNVIGLGIIFIDHDHRVLYFNRAMLKIWGFPPDEN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEECCCEEEEEECEEHEEECCCCCCC
LIGTRDVVLQRTIAPLLADPESYFAHIEEVLADRRSVSEQFEVRMKDGRIVTDISSVVES
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHC
GKGARGIGRVWIYEDVTEQRRVADQLIALAERDPLTNLYNRRRFHEELERMLAEATRRDL
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
EVGLVAIDLDGFKPINDRFGHQAGDEVLVGVAEGVARIIRRNEMFFRLGGDEFAMLVPDT
HEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCC
SEAELSELAARLVEAIDALHFTFAGESAGVTASIGIALFPHHGEGGEALMVAADQAMYRS
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEECCCCCCCCEEEEEEHHHHHHC
KSDGRNRWMVSGGKHGGNGESDRMAARNRIPDEPPREKD
CCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]