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The map label for this gene is erpA

Identifier: 119899048

GI number: 119899048

Start: 3040778

End: 3041128

Strand: Reverse

Name: erpA

Synonym: azo2758

Alternate gene names: 119899048

Gene position: 3041128-3040778 (Counterclockwise)

Preceding gene: 119899049

Following gene: 119899046

Centisome position: 69.49

GC content: 57.55

Gene sequence:

>351_bases
ATGAACGCAGCAGTTGAAACCCCCGAAATTCTCGTCTTCACCGACAACGCCGCCAACAAGGTGCGCGAACTCATCGATGA
GGAAGGCAATCCGGCGCTGAAGCTCCGCGTGTTCGTCACTGGGGGCGGCTGTTCCGGCTTCCAGTACGGCTTCACCTTCG
ATGAGGAAGTGAACGAAGACGACACCGCTTTCGAAAAGAACGGCGTCACCCTGCTGATCGATCCGATGAGCTATCAGTAC
CTTGTCGGCGCTGAAATCGATTACACCGAAGGGCTTGAAGGCTCGCAGTTCGTGATCCGCAACCCCAATGCCACCAGCAC
GTGCGGATGCGGTTCCTCGTTCTCCGCGTGA

Upstream 100 bases:

>100_bases
CCGATAACGGTAGGGAACTTGTCCGGCGCCTGATGATCGGATTTTGACGTGTGCGGATGGTTGGCGCATCATCCATTCGT
TCCCTGACAGAGGAAAACAT

Downstream 100 bases:

>100_bases
GTCCGATCTTGCGGCATCAATGAAAACGGGGCGCCTGGCGCCCCGTTTTCATTTGGTCTTCCTGCGCGTCACTGGGTCGC
GCTCGCCATCTGCGTGTTGT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MNAAVETPEILVFTDNAANKVRELIDEEGNPALKLRVFVTGGGCSGFQYGFTFDEEVNEDDTAFEKNGVTLLIDPMSYQY
LVGAEIDYTEGLEGSQFVIRNPNATSTCGCGSSFSA

Sequences:

>Translated_116_residues
MNAAVETPEILVFTDNAANKVRELIDEEGNPALKLRVFVTGGGCSGFQYGFTFDEEVNEDDTAFEKNGVTLLIDPMSYQY
LVGAEIDYTEGLEGSQFVIRNPNATSTCGCGSSFSA
>Mature_116_residues
MNAAVETPEILVFTDNAANKVRELIDEEGNPALKLRVFVTGGGCSGFQYGFTFDEEVNEDDTAFEKNGVTLLIDPMSYQY
LVGAEIDYTEGLEGSQFVIRNPNATSTCGCGSSFSA

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=118, Percent_Identity=39.8305084745763, Blast_Score=86, Evalue=8e-18,
Organism=Homo sapiens, GI52426768, Length=109, Percent_Identity=33.0275229357798, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786351, Length=105, Percent_Identity=72.3809523809524, Blast_Score=165, Evalue=7e-43,
Organism=Escherichia coli, GI1788877, Length=108, Percent_Identity=37.962962962963, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1787974, Length=105, Percent_Identity=35.2380952380952, Blast_Score=62, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=112, Percent_Identity=37.5, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=110, Percent_Identity=35.4545454545455, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=36.1904761904762, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649697, Length=82, Percent_Identity=48.780487804878, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24642263, Length=111, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_AZOSB (A1K969)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934261.1
- ProteinModelPortal:   A1K969
- SMR:   A1K969
- STRING:   A1K969
- GeneID:   4607600
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2758
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   A1K969
- ProtClustDB:   PRK13623
- BioCyc:   ASP62928:AZO2758-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12521; Mature: 12521

Theoretical pI: Translated: 3.73; Mature: 3.73

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAVETPEILVFTDNAANKVRELIDEEGNPALKLRVFVTGGGCSGFQYGFTFDEEVNED
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DTAFEKNGVTLLIDPMSYQYLVGAEIDYTEGLEGSQFVIRNPNATSTCGCGSSFSA
CCEEECCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAAVETPEILVFTDNAANKVRELIDEEGNPALKLRVFVTGGGCSGFQYGFTFDEEVNED
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DTAFEKNGVTLLIDPMSYQYLVGAEIDYTEGLEGSQFVIRNPNATSTCGCGSSFSA
CCEEECCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA