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The map label for this gene is panE2 [C]

Identifier: 119898898

GI number: 119898898

Start: 2889532

End: 2890509

Strand: Reverse

Name: panE2 [C]

Synonym: azo2607

Alternate gene names: 119898898

Gene position: 2890509-2889532 (Counterclockwise)

Preceding gene: 119898899

Following gene: 119898896

Centisome position: 66.05

GC content: 73.42

Gene sequence:

>978_bases
GTGAAGATCTGCCTGTATGGCGTCGGTGCGGTGGGCGGCCTGATCGGCGCCCGCCTGGCCGCCGCCGGCCATGCCCTCAA
CGCGGTCGCGCGCGGCGCCACACTGGAGGCGCTGCAGCGCGATGGCCTCGGCCTGGAGACGGCGGAAGGCCGCAGCCACT
TTCCGCTGCGCGCGGTGGCGGACCCCGCCGAACTCGGCGAGCAGGATCTCGTCATCGTCGCCGTCAAGCAGCCGGCGCTG
GCCGCGGTGGCGGCGGCGATCGGCCCCTTGATCGGACCGCGCACGCGGGTGCTGGTGGCGATGAACGGCGTGCCGTGGTG
GTTCTTCGACGGCCTGGCGGGGCCGCTTGCCGGCATCACGCTGGAAAGCGTGGACCCCGGCGGCGATCTGCGCAGCCGCA
TCCCCACCGCGCAGGTGATCGGCTGCGTGGTGCTCATCGCCTGCAACACCCCGGCGCCCGGGGTGTGCCGGCTCGGCTTC
GGCAACGGCCTCATCCTCGGCGACGCCCTCGGCGGCCCGCCCACCGCGCCCACCCGCGCGGCGGCGGAACTGCTTGCCGG
CGCCGGGCTGGACGTCAAGCTGTCGGACGGCATCCAGCGCGACATCTGGTACAAGCTGTGGGGCAACATGACGATGAACC
CGGTCTCCGCGCTGACCGGCGCCACCTCCGACCGCATCCTCGACGACCCGCTGGTCAATGCCTTCGTGGTGGCCGTGATG
GAGGAGGCCGCCGCGGTCGGCGAGCGTATCGGCTGCCCGGTGGCGCAGACTCCGCAGGCACGCAACGCCGTCACCCGCGA
ACTCGGCGCGATGCGCACCTCGATGCTGCAGGACGTGGAGGCCGGCCGCGCGCTGGAAATCGACGCGCTGCTCGGCGTGG
TGGTGGAGATCGCCGCCAGGGCCGGCGTGGCGGTGCCGAACGCGTCGGCGCTGCTGGGGCTGGTGCGGCTGTTCGGGCGG
GTACGCGGGCTGTATTGA

Upstream 100 bases:

>100_bases
CCGCCTTCACCCGGCTGGTCGACAAGGTCGATCCGGGTTACCGTCACTGAGCCACGCCGCCGGCATCGGACCGGCGACGG
ATCGAACGGAGGAGACGCGA

Downstream 100 bases:

>100_bases
TGCCTCAGCGCCAGCGGTGGCTGCGCGCCTTCACCACCAGGAACACTTCGCGCAGGAACAGCGCCAGCGACACGATCATC
GCCAGCATTGCCAGCACGAA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKICLYGVGAVGGLIGARLAAAGHALNAVARGATLEALQRDGLGLETAEGRSHFPLRAVADPAELGEQDLVIVAVKQPAL
AAVAAAIGPLIGPRTRVLVAMNGVPWWFFDGLAGPLAGITLESVDPGGDLRSRIPTAQVIGCVVLIACNTPAPGVCRLGF
GNGLILGDALGGPPTAPTRAAAELLAGAGLDVKLSDGIQRDIWYKLWGNMTMNPVSALTGATSDRILDDPLVNAFVVAVM
EEAAAVGERIGCPVAQTPQARNAVTRELGAMRTSMLQDVEAGRALEIDALLGVVVEIAARAGVAVPNASALLGLVRLFGR
VRGLY

Sequences:

>Translated_325_residues
MKICLYGVGAVGGLIGARLAAAGHALNAVARGATLEALQRDGLGLETAEGRSHFPLRAVADPAELGEQDLVIVAVKQPAL
AAVAAAIGPLIGPRTRVLVAMNGVPWWFFDGLAGPLAGITLESVDPGGDLRSRIPTAQVIGCVVLIACNTPAPGVCRLGF
GNGLILGDALGGPPTAPTRAAAELLAGAGLDVKLSDGIQRDIWYKLWGNMTMNPVSALTGATSDRILDDPLVNAFVVAVM
EEAAAVGERIGCPVAQTPQARNAVTRELGAMRTSMLQDVEAGRALEIDALLGVVVEIAARAGVAVPNASALLGLVRLFGR
VRGLY
>Mature_325_residues
MKICLYGVGAVGGLIGARLAAAGHALNAVARGATLEALQRDGLGLETAEGRSHFPLRAVADPAELGEQDLVIVAVKQPAL
AAVAAAIGPLIGPRTRVLVAMNGVPWWFFDGLAGPLAGITLESVDPGGDLRSRIPTAQVIGCVVLIACNTPAPGVCRLGF
GNGLILGDALGGPPTAPTRAAAELLAGAGLDVKLSDGIQRDIWYKLWGNMTMNPVSALTGATSDRILDDPLVNAFVVAVM
EEAAAVGERIGCPVAQTPQARNAVTRELGAMRTSMLQDVEAGRALEIDALLGVVVEIAARAGVAVPNASALLGLVRLFGR
VRGLY

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33235; Mature: 33235

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICLYGVGAVGGLIGARLAAAGHALNAVARGATLEALQRDGLGLETAEGRSHFPLRAVA
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DPAELGEQDLVIVAVKQPALAAVAAAIGPLIGPRTRVLVAMNGVPWWFFDGLAGPLAGIT
CHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCHHHCCE
LESVDPGGDLRSRIPTAQVIGCVVLIACNTPAPGVCRLGFGNGLILGDALGGPPTAPTRA
EECCCCCCHHHHHCCHHHHHHEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCHHH
AAELLAGAGLDVKLSDGIQRDIWYKLWGNMTMNPVSALTGATSDRILDDPLVNAFVVAVM
HHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
EEAAAVGERIGCPVAQTPQARNAVTRELGAMRTSMLQDVEAGRALEIDALLGVVVEIAAR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHH
AGVAVPNASALLGLVRLFGRVRGLY
CCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKICLYGVGAVGGLIGARLAAAGHALNAVARGATLEALQRDGLGLETAEGRSHFPLRAVA
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DPAELGEQDLVIVAVKQPALAAVAAAIGPLIGPRTRVLVAMNGVPWWFFDGLAGPLAGIT
CHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCHHHCCE
LESVDPGGDLRSRIPTAQVIGCVVLIACNTPAPGVCRLGFGNGLILGDALGGPPTAPTRA
EECCCCCCHHHHHCCHHHHHHEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCHHH
AAELLAGAGLDVKLSDGIQRDIWYKLWGNMTMNPVSALTGATSDRILDDPLVNAFVVAVM
HHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
EEAAAVGERIGCPVAQTPQARNAVTRELGAMRTSMLQDVEAGRALEIDALLGVVVEIAAR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHH
AGVAVPNASALLGLVRLFGRVRGLY
CCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]