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The map label for this gene is ubiG

Identifier: 119898880

GI number: 119898880

Start: 2868451

End: 2869152

Strand: Direct

Name: ubiG

Synonym: azo2589

Alternate gene names: 119898880

Gene position: 2868451-2869152 (Clockwise)

Preceding gene: 119898879

Following gene: 119898882

Centisome position: 65.55

GC content: 63.11

Gene sequence:

>702_bases
ATGAATACCAACGCCGACCCCGCCGAAGTCCAGAAATTCAGCGACCTCGCCCACCGCTGGTGGGACCCTGCGTCCGAATT
CAAGCCCCTGCACGAGATCAATCCGTTACGCCTCGACTGGATCGACGGCCACTGCGGCCTGGCGGGCAAGAAGGTGCTCG
ACGTCGGTTGCGGCGGCGGCCTGCTGTCCGAAGGCATGGCGCAGCGGGGCGCCGAGGTGTCCGGCATCGATCTGTCGGAA
AAAGCGCTCGGCGTCGCCCGGCTGCACCTGTACGAAAGCGGACTTCAGGTCGATTACCAGCTGACCAGCGCGGAAGCACA
CGCGGCCACTCATCCGGCACAGTTCGATGTGGTGACCTGCATGGAGATGCTGGAGCACGTGCCCAACCCCGAAAGCACGG
TGCACGCCTGCGCGCAGATGGCAAAGCCCGGCGGCGCGGTGTTCTTCTCCACGCTCAACCGCAATTTCAAAGCGTATCTG
TTCGCGGTGGTCGGCGCTGAATACCTGCTGAACCTGCTGCCACGCGGCACGCACGACTACGCCAAGTTCATCAAACCGTC
CGAACTCTCGCGGTACTGCCGCAACGCCGGCCTGGAGCTCGTCTCCCTGTCTGGCATGACCTACAACCCGATCACCAAGG
TCTATGCCCTGAGCCGCGACACCGATGTGAATTACATGGTGCACGCACGCAAGCTCGGGTAA

Upstream 100 bases:

>100_bases
CGCATCGCAATGAAAGCCCTGCTCCGGCAGGGCTTTTTCATTTTGTGCGAACCCTGCCGCCGGTTCCCGGCTGCACCTCC
CTGCCCTGCGAGGCCACCGA

Downstream 100 bases:

>100_bases
GACCGGCGGAAAGTTGGGCGGGAAGCGGCTCTGCTCCTGCCCCTCGGAGGCGGGATCGGACACAGCCATCCCGCCGCCCC
GGAACATGGTCTGTCCTGAT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNTNADPAEVQKFSDLAHRWWDPASEFKPLHEINPLRLDWIDGHCGLAGKKVLDVGCGGGLLSEGMAQRGAEVSGIDLSE
KALGVARLHLYESGLQVDYQLTSAEAHAATHPAQFDVVTCMEMLEHVPNPESTVHACAQMAKPGGAVFFSTLNRNFKAYL
FAVVGAEYLLNLLPRGTHDYAKFIKPSELSRYCRNAGLELVSLSGMTYNPITKVYALSRDTDVNYMVHARKLG

Sequences:

>Translated_233_residues
MNTNADPAEVQKFSDLAHRWWDPASEFKPLHEINPLRLDWIDGHCGLAGKKVLDVGCGGGLLSEGMAQRGAEVSGIDLSE
KALGVARLHLYESGLQVDYQLTSAEAHAATHPAQFDVVTCMEMLEHVPNPESTVHACAQMAKPGGAVFFSTLNRNFKAYL
FAVVGAEYLLNLLPRGTHDYAKFIKPSELSRYCRNAGLELVSLSGMTYNPITKVYALSRDTDVNYMVHARKLG
>Mature_233_residues
MNTNADPAEVQKFSDLAHRWWDPASEFKPLHEINPLRLDWIDGHCGLAGKKVLDVGCGGGLLSEGMAQRGAEVSGIDLSE
KALGVARLHLYESGLQVDYQLTSAEAHAATHPAQFDVVTCMEMLEHVPNPESTVHACAQMAKPGGAVFFSTLNRNFKAYL
FAVVGAEYLLNLLPRGTHDYAKFIKPSELSRYCRNAGLELVSLSGMTYNPITKVYALSRDTDVNYMVHARKLG

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=34.8360655737705, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1788564, Length=231, Percent_Identity=58.008658008658, Blast_Score=282, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=32.6359832635983, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=261, Percent_Identity=29.1187739463602, Blast_Score=113, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365311, Length=242, Percent_Identity=33.8842975206612, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24585589, Length=202, Percent_Identity=37.1287128712871, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_AZOSB (A1K8Q1)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934093.1
- ProteinModelPortal:   A1K8Q1
- SMR:   A1K8Q1
- STRING:   A1K8Q1
- GeneID:   4609443
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2589
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   A1K8Q1
- ProtClustDB:   PRK05134
- BioCyc:   ASP62928:AZO2589-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25564; Mature: 25564

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNADPAEVQKFSDLAHRWWDPASEFKPLHEINPLRLDWIDGHCGLAGKKVLDVGCGGG
CCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHCCCCEEEEEECCCCCCCCCEEEEECCCCH
LLSEGMAQRGAEVSGIDLSEKALGVARLHLYESGLQVDYQLTSAEAHAATHPAQFDVVTC
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCHHHHHHH
MEMLEHVPNPESTVHACAQMAKPGGAVFFSTLNRNFKAYLFAVVGAEYLLNLLPRGTHDY
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHH
AKFIKPSELSRYCRNAGLELVSLSGMTYNPITKVYALSRDTDVNYMVHARKLG
HHHCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MNTNADPAEVQKFSDLAHRWWDPASEFKPLHEINPLRLDWIDGHCGLAGKKVLDVGCGGG
CCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHCCCCEEEEEECCCCCCCCCEEEEECCCCH
LLSEGMAQRGAEVSGIDLSEKALGVARLHLYESGLQVDYQLTSAEAHAATHPAQFDVVTC
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCHHHHHHH
MEMLEHVPNPESTVHACAQMAKPGGAVFFSTLNRNFKAYLFAVVGAEYLLNLLPRGTHDY
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHH
AKFIKPSELSRYCRNAGLELVSLSGMTYNPITKVYALSRDTDVNYMVHARKLG
HHHCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA