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The map label for this gene is yegE [H]

Identifier: 119898748

GI number: 119898748

Start: 2711355

End: 2713823

Strand: Reverse

Name: yegE [H]

Synonym: azo2457

Alternate gene names: 119898748

Gene position: 2713823-2711355 (Counterclockwise)

Preceding gene: 119898749

Following gene: 119898747

Centisome position: 62.02

GC content: 69.91

Gene sequence:

>2469_bases
ATGCGTCTCCAGAGCTTTCTCACTCGCCTGATGTGGGCCTCGATGCTGCCGCTGATCGTCCTCGCGGCCTGGCTCGCGCT
GGCATCGCTGCGCGAAACGCGGGAGAACCGCGACCGCGAGGCGGCCAACCTCGCGCGCAACTTCATGACTGCAATCGACC
AGACCGTGCGTGCGCGGATCGGCGCGCTGACGGTGCTGGCGCACTCGCCGCTGGCGGACGACCCGGCCCAGCGCTCGGCC
CTGTACCGCGAGGCCGAGGGCCTCAAGCACAGCTTCGGCGGCGAGGTGATCCAGGCCGACCTGCAGATGCAGATGCTGTT
CAACACCCGCGTACCCTATGGCAGCGAGTTGCCGCGCCTGCCACGCCCGCGCGGCCGCGCGGCGGCGCCCACCGCGGTGG
AGACCGGCCAGCCCGCGGTGGGCGACCTGTTCGTCAGCCCGTTCAGTGGCAACCGCGTGGTGGCGATCGCGGTGCCGAGC
ATGGACAACGGCCGGCCGCGCTTCGTGCTGCTGACCGTCGTCGAGGCGGCGATGTTCCAGCAGCGCATCGAGCAGGTGTC
GCTGCCGCAGGGTTGGGCGCTGATGCTGGCCGACAGCACCGGCGAACCGATCGCGAAGGTGGGCGAGGAACTGGAGGCCG
ACGAGATCGCCGGCGGGCGCAGCTTCGAGGCCAGTTCGGAATATTCCGGCTGGCGCGTGGTGCTCGACATCCCGCGGCGT
GAATACCACGCCCCGGTGATCCAGGCAGCGTCGCTGCTGCTTGCGGTGATCGTGGGCGCGGTGGTGGCGGGCGCGCTCGG
CGGACGCGCCGCCAGCCGCCGGCTGAGCGCGGAGGTGGAGACGCTGGCGCGGGCGCGCAACGGCCAGCGCCCGGTGCTGC
ACATCCGCGAATTCGAGGCGGTGGCGCGCCTGCTGGCCGATTCCGACGCCGAGCGGCGCGCCGTGGCGGTGGCGCTGGAG
GACAGCGAACGGCGCTTCCGTGCAACCTTCGACCAGGCCGCCGTGGGGCTGGCGCTGGTGTCGCCCGAAGGCCACTGGCA
GCGGGTGAACCAGCGGCTGTGCGACATCGTCGGCTATGCGCGGGACGACCTGCTGCAGACCTCCTTCCAGGACATCACCC
ACCCGGACGACCTCGATCTGGATCTGGCGCAGATGAAACAGGTGCTGGCCGGCAAAATCAGCACGTATTCGATGGAAAAA
CGCTATCGCCGCGCCGACGGCAGACTGGTGTGGGTCAACCTCACCGTGTCGCTGGTGCGCGACGACGACGGTGCGCCGGA
TTACTTCATCTCGGTGATCGAGGACATCCAGCGCCGCAAGGAGGCCGAAGCCGCATTGCTGGCGCGCGAACAGACGCTGC
GCGAGGCTCAGCGGCTGGCGGGGCTGGGCAACTGGTCGTGGGACCTGCGGACCAACCAGCAGGTCTGGGCGGACGAAATC
TACCGCGTGTATGGGCGCGACCCGGCCAACGGCCCGCTGCCCTACGAGGAGGTTTCGCGCCAGTGCAGCGCCGAGAGCTG
GGAACGCCTGAACGCCGCTGTCGAGCGTTCGCTGGAAACCGGCGAAGGCTACGAATGCGACGTGGAGTTCGTGCGGGAGG
ACGGCTCGCACTGCTGGGCGACGGTGCGCGGGCAGCCGGTGCGCGACGCCAACGGCGTGATCGTCGAACTGAAGGGCACC
GTGCAGGACATCACCGAGCGCATGGAAACCGCCGCCGCGCTGCGCGAACTCAACGCCAGCCTGGAGCAACGCGTGGAGGC
GCGCACCGCCGAGCTGACCGCCGCCAACAAGGAACTGGACAGCTTCGCCTACGCGGTGTCGCACGACCTGCGCTCGCCGC
TGCGCGCGATGAGCGGCTTTGCCCAGGCGCTGCTGGAGGATTACGGCGACCGCCTGGACGCCGACGGGCGCGGCTTCCTC
GACCAGATCATCCTCGCGAGCCGCAAGATGAACGACCTGATCGAGGGCATCATGGAGCTGTCGCGCAGCACCGGCGGCGA
ACTGCATCGTGACGACATCGACGTTTCGGCCATGGCCGGCGCGATCCTCGCTGACCTCGCGCGGGTGGACCCGGATCGTG
CCGTACAGGTGGAGGTGGCGCCGGGGCTGCGCACCCGCGGCGACGCGCGCATGGTGGAGGCGGCGCTGCGCAACCTGCTC
GGCAACGCGTGGAAATACACCGGCAAGAGCCCGGAGCCGCGTATCGCCGTGGAGTACGCGGAGGTCGACGGCCTGCCCGG
CTTCTGTGTCGTCGATAACGGTGCCGGTTTCGACATGGCCTACGCCGAACAGCTGTTCAAGCCCTTCCGCCGCCTGCACC
GGCAGGACGAATTTCCCGGTATCGGCATCGGCCTTGCCACCGTGCAGCGCATCGTCCGCCGCCATGGCGGCGAGATCCGC
GCCGAGGGCCATCCGGGCGGCGGCGCGCGCTTCTGCCTGACACTGACGCCGCGCGACGGAAGGCGCTGA

Upstream 100 bases:

>100_bases
CTCATCGGTGCGCGCTCGCGGACGAGGGGGAAGACCAGGGAATGCTGCCTGAAACATTTACACGGCATGGACGGGCGCCA
GCCGGGGACGCAGGGTGGTG

Downstream 100 bases:

>100_bases
ACATGAGTCCGCGGCGGCGCTTCATCCTGCAGGCCACGGCTGCCTATGCCGTGCTGACGCTGGCCTGGATCCTGATCTCC
GACCGCGTCATCGCCGCGCT

Product: putative sensory box histidine kinase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MRLQSFLTRLMWASMLPLIVLAAWLALASLRETRENRDREAANLARNFMTAIDQTVRARIGALTVLAHSPLADDPAQRSA
LYREAEGLKHSFGGEVIQADLQMQMLFNTRVPYGSELPRLPRPRGRAAAPTAVETGQPAVGDLFVSPFSGNRVVAIAVPS
MDNGRPRFVLLTVVEAAMFQQRIEQVSLPQGWALMLADSTGEPIAKVGEELEADEIAGGRSFEASSEYSGWRVVLDIPRR
EYHAPVIQAASLLLAVIVGAVVAGALGGRAASRRLSAEVETLARARNGQRPVLHIREFEAVARLLADSDAERRAVAVALE
DSERRFRATFDQAAVGLALVSPEGHWQRVNQRLCDIVGYARDDLLQTSFQDITHPDDLDLDLAQMKQVLAGKISTYSMEK
RYRRADGRLVWVNLTVSLVRDDDGAPDYFISVIEDIQRRKEAEAALLAREQTLREAQRLAGLGNWSWDLRTNQQVWADEI
YRVYGRDPANGPLPYEEVSRQCSAESWERLNAAVERSLETGEGYECDVEFVREDGSHCWATVRGQPVRDANGVIVELKGT
VQDITERMETAAALRELNASLEQRVEARTAELTAANKELDSFAYAVSHDLRSPLRAMSGFAQALLEDYGDRLDADGRGFL
DQIILASRKMNDLIEGIMELSRSTGGELHRDDIDVSAMAGAILADLARVDPDRAVQVEVAPGLRTRGDARMVEAALRNLL
GNAWKYTGKSPEPRIAVEYAEVDGLPGFCVVDNGAGFDMAYAEQLFKPFRRLHRQDEFPGIGIGLATVQRIVRRHGGEIR
AEGHPGGGARFCLTLTPRDGRR

Sequences:

>Translated_822_residues
MRLQSFLTRLMWASMLPLIVLAAWLALASLRETRENRDREAANLARNFMTAIDQTVRARIGALTVLAHSPLADDPAQRSA
LYREAEGLKHSFGGEVIQADLQMQMLFNTRVPYGSELPRLPRPRGRAAAPTAVETGQPAVGDLFVSPFSGNRVVAIAVPS
MDNGRPRFVLLTVVEAAMFQQRIEQVSLPQGWALMLADSTGEPIAKVGEELEADEIAGGRSFEASSEYSGWRVVLDIPRR
EYHAPVIQAASLLLAVIVGAVVAGALGGRAASRRLSAEVETLARARNGQRPVLHIREFEAVARLLADSDAERRAVAVALE
DSERRFRATFDQAAVGLALVSPEGHWQRVNQRLCDIVGYARDDLLQTSFQDITHPDDLDLDLAQMKQVLAGKISTYSMEK
RYRRADGRLVWVNLTVSLVRDDDGAPDYFISVIEDIQRRKEAEAALLAREQTLREAQRLAGLGNWSWDLRTNQQVWADEI
YRVYGRDPANGPLPYEEVSRQCSAESWERLNAAVERSLETGEGYECDVEFVREDGSHCWATVRGQPVRDANGVIVELKGT
VQDITERMETAAALRELNASLEQRVEARTAELTAANKELDSFAYAVSHDLRSPLRAMSGFAQALLEDYGDRLDADGRGFL
DQIILASRKMNDLIEGIMELSRSTGGELHRDDIDVSAMAGAILADLARVDPDRAVQVEVAPGLRTRGDARMVEAALRNLL
GNAWKYTGKSPEPRIAVEYAEVDGLPGFCVVDNGAGFDMAYAEQLFKPFRRLHRQDEFPGIGIGLATVQRIVRRHGGEIR
AEGHPGGGARFCLTLTPRDGRR
>Mature_822_residues
MRLQSFLTRLMWASMLPLIVLAAWLALASLRETRENRDREAANLARNFMTAIDQTVRARIGALTVLAHSPLADDPAQRSA
LYREAEGLKHSFGGEVIQADLQMQMLFNTRVPYGSELPRLPRPRGRAAAPTAVETGQPAVGDLFVSPFSGNRVVAIAVPS
MDNGRPRFVLLTVVEAAMFQQRIEQVSLPQGWALMLADSTGEPIAKVGEELEADEIAGGRSFEASSEYSGWRVVLDIPRR
EYHAPVIQAASLLLAVIVGAVVAGALGGRAASRRLSAEVETLARARNGQRPVLHIREFEAVARLLADSDAERRAVAVALE
DSERRFRATFDQAAVGLALVSPEGHWQRVNQRLCDIVGYARDDLLQTSFQDITHPDDLDLDLAQMKQVLAGKISTYSMEK
RYRRADGRLVWVNLTVSLVRDDDGAPDYFISVIEDIQRRKEAEAALLAREQTLREAQRLAGLGNWSWDLRTNQQVWADEI
YRVYGRDPANGPLPYEEVSRQCSAESWERLNAAVERSLETGEGYECDVEFVREDGSHCWATVRGQPVRDANGVIVELKGT
VQDITERMETAAALRELNASLEQRVEARTAELTAANKELDSFAYAVSHDLRSPLRAMSGFAQALLEDYGDRLDADGRGFL
DQIILASRKMNDLIEGIMELSRSTGGELHRDDIDVSAMAGAILADLARVDPDRAVQVEVAPGLRTRGDARMVEAALRNLL
GNAWKYTGKSPEPRIAVEYAEVDGLPGFCVVDNGAGFDMAYAEQLFKPFRRLHRQDEFPGIGIGLATVQRIVRRHGGEIR
AEGHPGGGARFCLTLTPRDGRR

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=316, Percent_Identity=31.6455696202532, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=30.6306306306306, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=28.6885245901639, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=342, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=26.3392857142857, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 90807; Mature: 90807

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQSFLTRLMWASMLPLIVLAAWLALASLRETRENRDREAANLARNFMTAIDQTVRARI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALTVLAHSPLADDPAQRSALYREAEGLKHSFGGEVIQADLQMQMLFNTRVPYGSELPRL
HHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PRPRGRAAAPTAVETGQPAVGDLFVSPFSGNRVVAIAVPSMDNGRPRFVLLTVVEAAMFQ
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHH
QRIEQVSLPQGWALMLADSTGEPIAKVGEELEADEIAGGRSFEASSEYSGWRVVLDIPRR
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCCEEEEECCCC
EYHAPVIQAASLLLAVIVGAVVAGALGGRAASRRLSAEVETLARARNGQRPVLHIREFEA
HHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
VARLLADSDAERRAVAVALEDSERRFRATFDQAAVGLALVSPEGHWQRVNQRLCDIVGYA
HHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHH
RDDLLQTSFQDITHPDDLDLDLAQMKQVLAGKISTYSMEKRYRRADGRLVWVNLTVSLVR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEE
DDDGAPDYFISVIEDIQRRKEAEAALLAREQTLREAQRLAGLGNWSWDLRTNQQVWADEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHH
YRVYGRDPANGPLPYEEVSRQCSAESWERLNAAVERSLETGEGYECDVEFVREDGSHCWA
HHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEE
TVRGQPVRDANGVIVELKGTVQDITERMETAAALRELNASLEQRVEARTAELTAANKELD
EECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAYAVSHDLRSPLRAMSGFAQALLEDYGDRLDADGRGFLDQIILASRKMNDLIEGIMEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRSTGGELHRDDIDVSAMAGAILADLARVDPDRAVQVEVAPGLRTRGDARMVEAALRNLL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
GNAWKYTGKSPEPRIAVEYAEVDGLPGFCVVDNGAGFDMAYAEQLFKPFRRLHRQDEFPG
CCHHCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCC
IGIGLATVQRIVRRHGGEIRAEGHPGGGARFCLTLTPRDGRR
CCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRLQSFLTRLMWASMLPLIVLAAWLALASLRETRENRDREAANLARNFMTAIDQTVRARI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALTVLAHSPLADDPAQRSALYREAEGLKHSFGGEVIQADLQMQMLFNTRVPYGSELPRL
HHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PRPRGRAAAPTAVETGQPAVGDLFVSPFSGNRVVAIAVPSMDNGRPRFVLLTVVEAAMFQ
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHH
QRIEQVSLPQGWALMLADSTGEPIAKVGEELEADEIAGGRSFEASSEYSGWRVVLDIPRR
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCCEEEEECCCC
EYHAPVIQAASLLLAVIVGAVVAGALGGRAASRRLSAEVETLARARNGQRPVLHIREFEA
HHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
VARLLADSDAERRAVAVALEDSERRFRATFDQAAVGLALVSPEGHWQRVNQRLCDIVGYA
HHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHH
RDDLLQTSFQDITHPDDLDLDLAQMKQVLAGKISTYSMEKRYRRADGRLVWVNLTVSLVR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEE
DDDGAPDYFISVIEDIQRRKEAEAALLAREQTLREAQRLAGLGNWSWDLRTNQQVWADEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHH
YRVYGRDPANGPLPYEEVSRQCSAESWERLNAAVERSLETGEGYECDVEFVREDGSHCWA
HHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEE
TVRGQPVRDANGVIVELKGTVQDITERMETAAALRELNASLEQRVEARTAELTAANKELD
EECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAYAVSHDLRSPLRAMSGFAQALLEDYGDRLDADGRGFLDQIILASRKMNDLIEGIMEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRSTGGELHRDDIDVSAMAGAILADLARVDPDRAVQVEVAPGLRTRGDARMVEAALRNLL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
GNAWKYTGKSPEPRIAVEYAEVDGLPGFCVVDNGAGFDMAYAEQLFKPFRRLHRQDEFPG
CCHHCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCC
IGIGLATVQRIVRRHGGEIRAEGHPGGGARFCLTLTPRDGRR
CCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]