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The map label for this gene is yycF [H]

Identifier: 119898702

GI number: 119898702

Start: 2662346

End: 2662720

Strand: Reverse

Name: yycF [H]

Synonym: azo2411

Alternate gene names: 119898702

Gene position: 2662720-2662346 (Counterclockwise)

Preceding gene: 119898703

Following gene: 119898701

Centisome position: 60.85

GC content: 63.47

Gene sequence:

>375_bases
ATGACCAAGAAGATCCTGATCGCGGATGACGAACAGAACATCGTCATTTCGCTGGAATTCCTGATGAAGCGGGAGGGGTT
CACCGTTGTCGTCGCCACCGACGGCGACGAGGCGGTACGGATGATCCGCGCCGAGCAGCCCGACCTGGTGCTGCTCGACG
TGATGATGCCCAAGAAGAGCGGCTTCGAAGTCTGCCAGGAGATCAAGGCCGACCCCGCGCTGCAGGGCGTGCGCATCCTG
ATGCTGACCGCCAAGGGGCGCGATACCGAAGTGGCCAAGGGCCTCGCGCTCGGCGCCGACGCCTACATGACCAAACCGTT
CTCCACCCGCGATCTCGTCGCCCGCGTGCGCAGCATGCTGGGCATGGAAGCATGA

Upstream 100 bases:

>100_bases
TCCGGCCCCGGCGAAGGGTCGCGGTTCTCGTTTGTATTGCCACTGCCGTCGGAGAGCGGCGGGCTATGACTTAGAATGGT
GGGCGAGGGGAGAGGAACGC

Downstream 100 bases:

>100_bases
GCGCCCGCGCAGGGCGGCAGGGTAAGCGCTTCGCCCGCGCACGGAGGCCCCAAGGCGGCCGGAGCCAACCCGGCGCCGGC
GCCGCAGGCCCGGTCACGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MTKKILIADDEQNIVISLEFLMKREGFTVVVATDGDEAVRMIRAEQPDLVLLDVMMPKKSGFEVCQEIKADPALQGVRIL
MLTAKGRDTEVAKGLALGADAYMTKPFSTRDLVARVRSMLGMEA

Sequences:

>Translated_124_residues
MTKKILIADDEQNIVISLEFLMKREGFTVVVATDGDEAVRMIRAEQPDLVLLDVMMPKKSGFEVCQEIKADPALQGVRIL
MLTAKGRDTEVAKGLALGADAYMTKPFSTRDLVARVRSMLGMEA
>Mature_123_residues
TKKILIADDEQNIVISLEFLMKREGFTVVVATDGDEAVRMIRAEQPDLVLLDVMMPKKSGFEVCQEIKADPALQGVRILM
LTAKGRDTEVAKGLALGADAYMTKPFSTRDLVARVRSMLGMEA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=38.3333333333333, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=40.1709401709402, Blast_Score=89, Evalue=8e-20,
Organism=Escherichia coli, GI2367329, Length=118, Percent_Identity=44.0677966101695, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=35.2941176470588, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=33.8842975206612, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=38.0165289256198, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=36.7521367521368, Blast_Score=76, Evalue=6e-16,
Organism=Escherichia coli, GI1787229, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=28.2051282051282, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13674; Mature: 13543

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKILIADDEQNIVISLEFLMKREGFTVVVATDGDEAVRMIRAEQPDLVLLDVMMPKKS
CCCEEEEEECCCCEEEEEEHEECCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCC
GFEVCQEIKADPALQGVRILMLTAKGRDTEVAKGLALGADAYMTKPFSTRDLVARVRSML
CHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHCEEECCCCEEECCCCHHHHHHHHHHHH
GMEA
CCCC
>Mature Secondary Structure 
TKKILIADDEQNIVISLEFLMKREGFTVVVATDGDEAVRMIRAEQPDLVLLDVMMPKKS
CCEEEEEECCCCEEEEEEHEECCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCC
GFEVCQEIKADPALQGVRILMLTAKGRDTEVAKGLALGADAYMTKPFSTRDLVARVRSML
CHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHCEEECCCCEEECCCCHHHHHHHHHHHH
GMEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]