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The map label for this gene is glgC [H]

Identifier: 119898522

GI number: 119898522

Start: 2444681

End: 2445784

Strand: Reverse

Name: glgC [H]

Synonym: azo2231

Alternate gene names: 119898522

Gene position: 2445784-2444681 (Counterclockwise)

Preceding gene: 119898523

Following gene: 119898519

Centisome position: 55.89

GC content: 66.39

Gene sequence:

>1104_bases
ATGGCGAAGGGAATGATACTGGCGGCGGGGCAGGGCACCCGCGTACGGCCGCTGACCAAGTACCTGCCCAAACCGATGGT
GCCCATCCTCGGCAAACCGGTGCTGGAATACCTGATCGAGCATCTGGCGCGCTACGGCGTGGACGAGATCATGATCAACG
TGGCCTACAACCACTACAAGATCGAGGACTACTTCGGCGACGGCCATCGCTGGGGCGTGCAGATCGGCTATTCCTACGAG
GGTGTGCGCGAACACGGCGAGGTCGTGCCACGCCCGCTCGGCTCGGCCGGGGGGATGCGCAAGATCCAGGACTTCAGCGG
CTTCTTCGACCAGACCACGCTGGTGGTGTGCGGCGACGCGATCGTCGATCTCGACATCCGCGCGGCACTGGACGAACACC
GCCTGAAGGGCGCGCTTGCCAGCGTGATCACGCTCGAGGTGCCGCGCGAACAGGTGCAGAACTATGGCGTGGTGGTGGCC
GACGGGGACGGGCGGGTGCTTTCCTTCCAGGAAAAACCCAGCCCCGAGGCGGCGCTGTCCACCCATGCCAGCACCGGTAT
CTACGTGCTGGAACCGGAGGTGATCGATCTCGTTCCGCCCGGCGAGGCCTTCGACATCGGCAGCCAGCTGTTTCCGATGC
TGGTGGAAAAGTCCCTGCCGTTCTTCGCCCAGAAGCGCTTCTTCAACTGGATCGACATCGGCCGCCTGAGCGACTACTGG
TCGGTATTGCAGCGCGTGCTGCGCGGCGAGGTGGCGCAAATGGACATGCCGGGGCGCGAGGTCCGGCCGGGCGTGTGGGT
CGGCCTCAACACCTCGATTGCGTGGGAGAGCGTGCAGATCGTGGGGCCGGTGCACATCGGCTCCGGGGTGCGGATCGAGC
CCGGCGCCTCGGTGATCGGCCCGAGCTGGATCGGCCACGGCAGCCACCTGCGGCCGGGGGCCCGGGTGGAGCGCAGCATC
CTCTTTCCCTACACGCGCATCGGCGAGGGGCAACGCTTCATCGACAAGATCGTGTCGCCGCAATACTGCGTGGATCGTTC
CGGGGAGACGCTCTACGTGGGCGACGATACCGCGGCGCTGCGCTGGGGCGATGCCCGCGGTTGA

Upstream 100 bases:

>100_bases
CGCAACATCTACGAGCCTTCGGTGCTGCGCGCCGCAGGCATCGAATACCACGGCATCGGCCGCCCGTGATCATCGCCGCG
ACAACGACAGGAGAGACTGC

Downstream 100 bases:

>100_bases
GCGCGGCGGCAGATGATGCGGGCGGCGGGCGGCTCAGCCGCCTTGCCGCTTGCCCGCCGTGCTGCCGTGCTCGTTCTTCC
ACACCCCGCGCAGGTTGGTG

Product: putative mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: ADP-glucose pyrophosphorylase; ADPGlc PPase; ADP-glucose synthase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAKGMILAAGQGTRVRPLTKYLPKPMVPILGKPVLEYLIEHLARYGVDEIMINVAYNHYKIEDYFGDGHRWGVQIGYSYE
GVREHGEVVPRPLGSAGGMRKIQDFSGFFDQTTLVVCGDAIVDLDIRAALDEHRLKGALASVITLEVPREQVQNYGVVVA
DGDGRVLSFQEKPSPEAALSTHASTGIYVLEPEVIDLVPPGEAFDIGSQLFPMLVEKSLPFFAQKRFFNWIDIGRLSDYW
SVLQRVLRGEVAQMDMPGREVRPGVWVGLNTSIAWESVQIVGPVHIGSGVRIEPGASVIGPSWIGHGSHLRPGARVERSI
LFPYTRIGEGQRFIDKIVSPQYCVDRSGETLYVGDDTAALRWGDARG

Sequences:

>Translated_367_residues
MAKGMILAAGQGTRVRPLTKYLPKPMVPILGKPVLEYLIEHLARYGVDEIMINVAYNHYKIEDYFGDGHRWGVQIGYSYE
GVREHGEVVPRPLGSAGGMRKIQDFSGFFDQTTLVVCGDAIVDLDIRAALDEHRLKGALASVITLEVPREQVQNYGVVVA
DGDGRVLSFQEKPSPEAALSTHASTGIYVLEPEVIDLVPPGEAFDIGSQLFPMLVEKSLPFFAQKRFFNWIDIGRLSDYW
SVLQRVLRGEVAQMDMPGREVRPGVWVGLNTSIAWESVQIVGPVHIGSGVRIEPGASVIGPSWIGHGSHLRPGARVERSI
LFPYTRIGEGQRFIDKIVSPQYCVDRSGETLYVGDDTAALRWGDARG
>Mature_366_residues
AKGMILAAGQGTRVRPLTKYLPKPMVPILGKPVLEYLIEHLARYGVDEIMINVAYNHYKIEDYFGDGHRWGVQIGYSYEG
VREHGEVVPRPLGSAGGMRKIQDFSGFFDQTTLVVCGDAIVDLDIRAALDEHRLKGALASVITLEVPREQVQNYGVVVAD
GDGRVLSFQEKPSPEAALSTHASTGIYVLEPEVIDLVPPGEAFDIGSQLFPMLVEKSLPFFAQKRFFNWIDIGRLSDYWS
VLQRVLRGEVAQMDMPGREVRPGVWVGLNTSIAWESVQIVGPVHIGSGVRIEPGASVIGPSWIGHGSHLRPGARVERSIL
FPYTRIGEGQRFIDKIVSPQYCVDRSGETLYVGDDTAALRWGDARG

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=345, Percent_Identity=28.9855072463768, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI11761619, Length=341, Percent_Identity=29.0322580645161, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1788351, Length=199, Percent_Identity=30.1507537688442, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789837, Length=291, Percent_Identity=24.3986254295533, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790224, Length=241, Percent_Identity=28.2157676348548, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509979, Length=349, Percent_Identity=29.512893982808, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=339, Percent_Identity=29.2035398230088, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI133931050, Length=323, Percent_Identity=27.8637770897833, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=330, Percent_Identity=29.6969696969697, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355443, Length=322, Percent_Identity=27.0186335403727, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24644084, Length=322, Percent_Identity=27.0186335403727, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24653912, Length=205, Percent_Identity=31.219512195122, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005836
- InterPro:   IPR011831
- InterPro:   IPR023049
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.27 [H]

Molecular weight: Translated: 40499; Mature: 40368

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGMILAAGQGTRVRPLTKYLPKPMVPILGKPVLEYLIEHLARYGVDEIMINVAYNHYK
CCCCEEEECCCCCCCCHHHHHCCCCCCHHCCHHHHHHHHHHHHHCCHHHEEEEEEECEEE
IEDYFGDGHRWGVQIGYSYEGVREHGEVVPRPLGSAGGMRKIQDFSGFFDQTTLVVCGDA
EEEEECCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCHHCCEEEEEECCE
IVDLDIRAALDEHRLKGALASVITLEVPREQVQNYGVVVADGDGRVLSFQEKPSPEAALS
EEEEHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCEEEECCCCCEEEECCCCCCHHHHH
THASTGIYVLEPEVIDLVPPGEAFDIGSQLFPMLVEKSLPFFAQKRFFNWIDIGRLSDYW
HCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCHHHHH
SVLQRVLRGEVAQMDMPGREVRPGVWVGLNTSIAWESVQIVGPVHIGSGVRIEPGASVIG
HHHHHHHCCHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEEECCCCEECCCCCCCC
PSWIGHGSHLRPGARVERSILFPYTRIGEGQRFIDKIVSPQYCVDRSGETLYVGDDTAAL
CCCCCCCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHCCCCCHHCCCCCEEEECCCCEEE
RWGDARG
ECCCCCC
>Mature Secondary Structure 
AKGMILAAGQGTRVRPLTKYLPKPMVPILGKPVLEYLIEHLARYGVDEIMINVAYNHYK
CCCEEEECCCCCCCCHHHHHCCCCCCHHCCHHHHHHHHHHHHHCCHHHEEEEEEECEEE
IEDYFGDGHRWGVQIGYSYEGVREHGEVVPRPLGSAGGMRKIQDFSGFFDQTTLVVCGDA
EEEEECCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCHHCCEEEEEECCE
IVDLDIRAALDEHRLKGALASVITLEVPREQVQNYGVVVADGDGRVLSFQEKPSPEAALS
EEEEHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCEEEECCCCCEEEECCCCCCHHHHH
THASTGIYVLEPEVIDLVPPGEAFDIGSQLFPMLVEKSLPFFAQKRFFNWIDIGRLSDYW
HCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCHHHHH
SVLQRVLRGEVAQMDMPGREVRPGVWVGLNTSIAWESVQIVGPVHIGSGVRIEPGASVIG
HHHHHHHCCHHHHCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEEECCCCEECCCCCCCC
PSWIGHGSHLRPGARVERSILFPYTRIGEGQRFIDKIVSPQYCVDRSGETLYVGDDTAAL
CCCCCCCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHCCCCCHHCCCCCEEEECCCCEEE
RWGDARG
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA