Click here to switch to the map view.

The map label for this gene is msrB [H]

Identifier: 119898461

GI number: 119898461

Start: 2378368

End: 2378784

Strand: Direct

Name: msrB [H]

Synonym: azo2170

Alternate gene names: 119898461

Gene position: 2378368-2378784 (Clockwise)

Preceding gene: 119898460

Following gene: 119898462

Centisome position: 54.35

GC content: 63.55

Gene sequence:

>417_bases
ATGAAGCGCAAGATCGAAAAGCCCGATGCCGAGTGGCGCCAGGCGCTGACGCCCGAGCAGTACCACGTCACCCGCGAAAA
GGGCACCGAGCGCGCGTTCACCGGCAAGTACTGGAACACCTGGACCAAAGGCACCTACAACTGCGCGTGCTGCGGCGCTC
CGCTGTTCGACGCAGCGCACAAGTTCGACGCCGGCTGCGGATGGCCGAGCTTCTGGACCGCGGCCGAACCGGAAAACGTT
GAAACCGCTGAGGATTTCAGCCACTTCATGCACCGCACCGAGGTGCTGTGCCACCAATGCGGTGCACATCTCGGTCATGT
GTTCGAAGACGGTCCCCAACCCACCGGACTGCGCTACTGCATCAACTCCGCCTCGATCGAACACGTCCCCGAAGCGGACA
GCGACACCGGGGCCTGA

Upstream 100 bases:

>100_bases
CACCGGACGGCGAAGTCGCCCACGCCGAGATGCCGGAAGAGCACGCCGAGCAGATGCCGCGTCACCTTCACTGACGACGA
CGCCGGACAGGAGAACCGCC

Downstream 100 bases:

>100_bases
TTGTCCTCAAGCTGACCGCCCGCCTGCCGTTACATCACGCAATGCAGTGCCCGCCGAGGCTGGCAAGACGGCGCAGCATT
CCACAATCACAACGCGGAGA

Product: peptide methionine sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKRKIEKPDAEWRQALTPEQYHVTREKGTERAFTGKYWNTWTKGTYNCACCGAPLFDAAHKFDAGCGWPSFWTAAEPENV
ETAEDFSHFMHRTEVLCHQCGAHLGHVFEDGPQPTGLRYCINSASIEHVPEADSDTGA

Sequences:

>Translated_138_residues
MKRKIEKPDAEWRQALTPEQYHVTREKGTERAFTGKYWNTWTKGTYNCACCGAPLFDAAHKFDAGCGWPSFWTAAEPENV
ETAEDFSHFMHRTEVLCHQCGAHLGHVFEDGPQPTGLRYCINSASIEHVPEADSDTGA
>Mature_138_residues
MKRKIEKPDAEWRQALTPEQYHVTREKGTERAFTGKYWNTWTKGTYNCACCGAPLFDAAHKFDAGCGWPSFWTAAEPENV
ETAEDFSHFMHRTEVLCHQCGAHLGHVFEDGPQPTGLRYCINSASIEHVPEADSDTGA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=133, Percent_Identity=53.3834586466165, Blast_Score=153, Evalue=5e-38,
Organism=Homo sapiens, GI301336162, Length=133, Percent_Identity=53.3834586466165, Blast_Score=153, Evalue=5e-38,
Organism=Homo sapiens, GI73089054, Length=133, Percent_Identity=53.3834586466165, Blast_Score=153, Evalue=5e-38,
Organism=Homo sapiens, GI37620216, Length=133, Percent_Identity=53.3834586466165, Blast_Score=153, Evalue=5e-38,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=49.21875, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=50.4132231404959, Blast_Score=133, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17553450, Length=132, Percent_Identity=49.2424242424242, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=132, Percent_Identity=49.2424242424242, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=43.75, Blast_Score=110, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=51.9685039370079, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI45553335, Length=136, Percent_Identity=50.7352941176471, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356369, Length=136, Percent_Identity=50.7352941176471, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24645801, Length=147, Percent_Identity=47.6190476190476, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI221378664, Length=130, Percent_Identity=49.2307692307692, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24645804, Length=147, Percent_Identity=47.6190476190476, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI221378662, Length=137, Percent_Identity=46.7153284671533, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15521; Mature: 15521

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIEKPDAEWRQALTPEQYHVTREKGTERAFTGKYWNTWTKGTYNCACCGAPLFDAAH
CCCCCCCCCHHHHHCCCCCHHEEHHHCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
KFDAGCGWPSFWTAAEPENVETAEDFSHFMHRTEVLCHQCGAHLGHVFEDGPQPTGLRYC
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
INSASIEHVPEADSDTGA
HCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRKIEKPDAEWRQALTPEQYHVTREKGTERAFTGKYWNTWTKGTYNCACCGAPLFDAAH
CCCCCCCCCHHHHHCCCCCHHEEHHHCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
KFDAGCGWPSFWTAAEPENVETAEDFSHFMHRTEVLCHQCGAHLGHVFEDGPQPTGLRYC
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
INSASIEHVPEADSDTGA
HCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]