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The map label for this gene is yfbQ [H]

Identifier: 119898373

GI number: 119898373

Start: 2288377

End: 2289705

Strand: Reverse

Name: yfbQ [H]

Synonym: azo2082

Alternate gene names: 119898373

Gene position: 2289705-2288377 (Counterclockwise)

Preceding gene: 119898375

Following gene: 119898372

Centisome position: 52.32

GC content: 64.94

Gene sequence:

>1329_bases
ATGAACGCGGCGAAGACTCTGAATCTGGCACCAGCCCCCACCGAACCCCTGGTTGCGGTCGAGGCCGGTGCAGCCGCCGC
GAGTCCGTCACCGCTCTCCACGCCGCGCGCGGTGCGCAAATCCGCCAAGCTGGCGGACGTCTGCTACGACATCCGCGGTC
CGGTGCTCACGCGCGCAAAGCAGATGGAGGACGAGGGCCACAAGATCATCAAGCTGAACATCGGCAACCTCGCCTCGTTC
GGCTTCGACGCGCCCGAAGAAATCCAGATGGACATGATCCGCAACCTGCCGAATTCGGCGGGCTACTCGGATTCCAAGGG
CATCTTCGCCGCGCGCAAGGCGGTGATGCACTACACCCAGCAGAAGCACATCAAGGGTGTGGGCATGGAAGACATCTACA
TCGGCAACGGCGTGTCCGAGCTGATCGTGATGGCGATGAACGCGCTGCTCAACCCGGGCGACGAAGTGCTGGTTCCCGCG
CCGGACTATCCGCTGTGGACCGCGGCGGTGAGCCTTTCGGGCGGCACGCCGGTGCATTACATCTGCGACGAAGGCAACGG
CTGGCTGCCCGATCTGGCCGACATGCGCGAGCGCATCACGCCCAACACCCGCGCGATCGTGGTGATCAACCCGAATAACC
CGACCGGCGCGCTGTACCCCGAAGCGGTGCTGAAAGGCATCATCGCGCTGGCCCGCGAGTTCGACCTGATCCTGTACGCC
GACGAGGTGTACGACAAGGTGTTGTACGAAGGCGCAGTGCACACCTCGCTGGCGGCTTTGTCGGAAGACGTGCTGACCAT
CATCTTCAACGGCCTGTCGAAAAACTACCGTTCCTGCGGTTACCGTGCCGGCTGGATGGTGGTGTGTGGCGACAAGCGCA
ACGCCCAGGACTACATCGAAGGCCTCAACATGCTGGCCTCGATGCGCCTGTGCGCCAACGTGCCGGGCCAATACGCGATC
CAGACCGCACTGGGCGGCTACCAGAGCATCGACGACCTCGTCGCCGACGGCGGCCGGCTGCGGCGCCAGCGCGACCTCGC
GCACGAACTGATCACCGCCATCCCCGGCGTGAGCTGCGTCAAGCCCAAGGCGGCGCTGTACATGTTCCCGCGCCTCGATC
CGAAGATCTACCCGATCGAGGACGATCAGGCCTTCATTGCCGAACTGCTCGAAGCCGAGCGCGTGCTGCTGGTGCAGGGC
ACGGGCTTCAACTGGCCCGATCCGGACCACTTCCGCCTGGTCTTCCTGCCGCACGAGGACGACCTGCGCGACGCCATCGG
CCGCGTTGCGCGCTTCCTCGAAGGCTATCGCAAGCGCCACGGCACCTGA

Upstream 100 bases:

>100_bases
AACAGCCTTTCGCGCGCGGCGGCGGCTGCGCGTGGATGCTCCCGACCGATGCCCGGCAATTCCGCCGGCCCATCCCATCT
ACGCTTTACAGGACAAGGAC

Downstream 100 bases:

>100_bases
ACCTCACCGAACCACCTTTCACACGACAGAAACGGAAGCACTGAATGAAACCGATCAACGTTGGCCTGCTGGGCATCGGA
ACCGTCGGCGGCGGTACCTT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNAAKTLNLAPAPTEPLVAVEAGAAAASPSPLSTPRAVRKSAKLADVCYDIRGPVLTRAKQMEDEGHKIIKLNIGNLASF
GFDAPEEIQMDMIRNLPNSAGYSDSKGIFAARKAVMHYTQQKHIKGVGMEDIYIGNGVSELIVMAMNALLNPGDEVLVPA
PDYPLWTAAVSLSGGTPVHYICDEGNGWLPDLADMRERITPNTRAIVVINPNNPTGALYPEAVLKGIIALAREFDLILYA
DEVYDKVLYEGAVHTSLAALSEDVLTIIFNGLSKNYRSCGYRAGWMVVCGDKRNAQDYIEGLNMLASMRLCANVPGQYAI
QTALGGYQSIDDLVADGGRLRRQRDLAHELITAIPGVSCVKPKAALYMFPRLDPKIYPIEDDQAFIAELLEAERVLLVQG
TGFNWPDPDHFRLVFLPHEDDLRDAIGRVARFLEGYRKRHGT

Sequences:

>Translated_442_residues
MNAAKTLNLAPAPTEPLVAVEAGAAAASPSPLSTPRAVRKSAKLADVCYDIRGPVLTRAKQMEDEGHKIIKLNIGNLASF
GFDAPEEIQMDMIRNLPNSAGYSDSKGIFAARKAVMHYTQQKHIKGVGMEDIYIGNGVSELIVMAMNALLNPGDEVLVPA
PDYPLWTAAVSLSGGTPVHYICDEGNGWLPDLADMRERITPNTRAIVVINPNNPTGALYPEAVLKGIIALAREFDLILYA
DEVYDKVLYEGAVHTSLAALSEDVLTIIFNGLSKNYRSCGYRAGWMVVCGDKRNAQDYIEGLNMLASMRLCANVPGQYAI
QTALGGYQSIDDLVADGGRLRRQRDLAHELITAIPGVSCVKPKAALYMFPRLDPKIYPIEDDQAFIAELLEAERVLLVQG
TGFNWPDPDHFRLVFLPHEDDLRDAIGRVARFLEGYRKRHGT
>Mature_442_residues
MNAAKTLNLAPAPTEPLVAVEAGAAAASPSPLSTPRAVRKSAKLADVCYDIRGPVLTRAKQMEDEGHKIIKLNIGNLASF
GFDAPEEIQMDMIRNLPNSAGYSDSKGIFAARKAVMHYTQQKHIKGVGMEDIYIGNGVSELIVMAMNALLNPGDEVLVPA
PDYPLWTAAVSLSGGTPVHYICDEGNGWLPDLADMRERITPNTRAIVVINPNNPTGALYPEAVLKGIIALAREFDLILYA
DEVYDKVLYEGAVHTSLAALSEDVLTIIFNGLSKNYRSCGYRAGWMVVCGDKRNAQDYIEGLNMLASMRLCANVPGQYAI
QTALGGYQSIDDLVADGGRLRRQRDLAHELITAIPGVSCVKPKAALYMFPRLDPKIYPIEDDQAFIAELLEAERVLLVQG
TGFNWPDPDHFRLVFLPHEDDLRDAIGRVARFLEGYRKRHGT

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=466, Percent_Identity=27.8969957081545, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI215599424, Length=408, Percent_Identity=29.4117647058824, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4507369, Length=432, Percent_Identity=25.9259259259259, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=27.0089285714286, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI56713254, Length=188, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI56713256, Length=170, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI169881281, Length=145, Percent_Identity=28.2758620689655, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=63.3416458852868, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=26.6304347826087, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786816, Length=272, Percent_Identity=24.2647058823529, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=29.1338582677165, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=476, Percent_Identity=26.6806722689076, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71981215, Length=296, Percent_Identity=28.3783783783784, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=179, Percent_Identity=28.4916201117318, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=179, Percent_Identity=28.4916201117318, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=167, Percent_Identity=29.3413173652695, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=473, Percent_Identity=26.215644820296, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=402, Percent_Identity=27.363184079602, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=308, Percent_Identity=23.7012987012987, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=27.7486910994764, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45551451, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641770, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641760, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641768, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641766, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641764, Length=467, Percent_Identity=27.1948608137045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 48363; Mature: 48363

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAKTLNLAPAPTEPLVAVEAGAAAASPSPLSTPRAVRKSAKLADVCYDIRGPVLTRAK
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
QMEDEGHKIIKLNIGNLASFGFDAPEEIQMDMIRNLPNSAGYSDSKGIFAARKAVMHYTQ
HHHCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QKHIKGVGMEDIYIGNGVSELIVMAMNALLNPGDEVLVPAPDYPLWTAAVSLSGGTPVHY
HHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCCEEE
ICDEGNGWLPDLADMRERITPNTRAIVVINPNNPTGALYPEAVLKGIIALAREFDLILYA
EEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEH
DEVYDKVLYEGAVHTSLAALSEDVLTIIFNGLSKNYRSCGYRAGWMVVCGDKRNAQDYIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
GLNMLASMRLCANVPGQYAIQTALGGYQSIDDLVADGGRLRRQRDLAHELITAIPGVSCV
HHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
KPKAALYMFPRLDPKIYPIEDDQAFIAELLEAERVLLVQGTGFNWPDPDHFRLVFLPHED
CCCHHEEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCH
DLRDAIGRVARFLEGYRKRHGT
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAAKTLNLAPAPTEPLVAVEAGAAAASPSPLSTPRAVRKSAKLADVCYDIRGPVLTRAK
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
QMEDEGHKIIKLNIGNLASFGFDAPEEIQMDMIRNLPNSAGYSDSKGIFAARKAVMHYTQ
HHHCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QKHIKGVGMEDIYIGNGVSELIVMAMNALLNPGDEVLVPAPDYPLWTAAVSLSGGTPVHY
HHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCCEEE
ICDEGNGWLPDLADMRERITPNTRAIVVINPNNPTGALYPEAVLKGIIALAREFDLILYA
EEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEH
DEVYDKVLYEGAVHTSLAALSEDVLTIIFNGLSKNYRSCGYRAGWMVVCGDKRNAQDYIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
GLNMLASMRLCANVPGQYAIQTALGGYQSIDDLVADGGRLRRQRDLAHELITAIPGVSCV
HHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
KPKAALYMFPRLDPKIYPIEDDQAFIAELLEAERVLLVQGTGFNWPDPDHFRLVFLPHED
CCCHHEEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCH
DLRDAIGRVARFLEGYRKRHGT
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]