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The map label for this gene is prkA [H]

Identifier: 119898364

GI number: 119898364

Start: 2275699

End: 2277621

Strand: Direct

Name: prkA [H]

Synonym: azo2073

Alternate gene names: 119898364

Gene position: 2275699-2277621 (Clockwise)

Preceding gene: 119898357

Following gene: 119898365

Centisome position: 52.0

GC content: 57.77

Gene sequence:

>1923_bases
ATGACCATCTTCAACGCCTATCAAGCCCGTTTCGAAGCAGCACGCGAGGAAGAGATGTCGATCCAGGAATACCTGGATCT
GTGCAAGACAGACCGCTCTGCGTATGCGACTGCAGCGGAACGCATGCTGATGGCGATTGGCGAACCGGAGCTGGTCGATA
CCCGGCTGGATCCCCGCCTTTCGCGCATCTTTTCCAACAAGGTGCTCAAGCTCTATCCGGCCTTCCGCGACTTCTATGGG
ATGGAAGAGGTCATCGAGCACATCGTGTCATATTTCCGACACGCGGCGCAGGGGCTGGAGGAAAAGAAACAGATTCTCTA
TCTCCTCGGTCCTGTGGGCGGCGGCAAGTCCTCGCTGGCGGAAAAACTGAAAAGCCTGATCGAGAAAGTGCCCTTCTACG
CCATCAAGGGTTCGCCGGTCCATGAGTCCCCGCTGGGGCTTTTCGACGTGGACGAAGACGGCCGGATACTGGAAGACGAC
TACGGGATTCCACGCCGCTACCTGAACACGATCATGAGTCCGTGGGCGGTCAAGCGCCTGCACGAATTCAACGGCGACAT
CACCCGCTTCCGCGTCATCAAGCTCAACCCGTCGGTGTTGCGGCAGATCGCCGTGGCCAAGACGGAGCCGGGTGACGAAA
ACAACCAGGACATCTCCTCGCTGGTGGGCAAGATCGACATCCGCATGCTGGAGCAGTTCTCGCAGGACGACCCGGATGCC
TACAGCTACTCCGGGGGCTTGTGCCTGGCAAACCGGGGCTTGCTCGAGTTCGTCGAGATGTTCAAGGCGCCGATCAAGGT
GCTGCATCCTTTGCTGACCGCAACGCAGGAAGGCAACTACAAGGGCACCGAGGGTTTCGGTGCGATTCCGTTCGACGGCA
TCGTGATGGCGCACTCGAACGAATCCGAATGGGTGGCGTTCAAGAACAACAAGAACAACGAGGCCTTCCTCGACCGCATC
TACACGGTCAAGGTGCCGTACTGCCTGCGGATGTCCGACGAAATCCGGATCTACGACAAGTTGCTCACCCACAGCTCGCT
TTCGGAAGCACCGTGCGCGCCGGACACCTTGAAGATGATGGCGCAGTTCTCGGTACTGTCGCGTCTGAAAGAGCCGGAGA
ATTCCAGCATCTATTCCAAGATGCGGGTCTACGACGGTGAAAACCTGAAGGACACCGACCCCAAGGCCAAGAGCTACCAG
GAGTATCGCGACTACGCCGGCGTCGACGAGGGCATGACCGGGCTATCCACACGCTTTGCCTTCAAGGTGCTGTCCAAGGT
ATTCAACTTCGATCACCGCGAGGTCGCTGCCAACCCGGTGCACCTGATGTACGTGCTGGAACAGCAGATCGAGCAGGAAC
AGTTCATGCCCGAAACCGAAGCGCGCTACATGGGCTTCATCAAGGAATACCTCGCTCCGCGCTACGCCGAGTTCATCGGC
AAGGAAATCCAGACCGCGTACCTGGAGAGCTATTCGGAATACGGGCAGAACATCTTCGATCGCTACGTGATCTACGCCGA
TTTCTGGATCCAGGATCAGGAATTCCGCGACCCCAACACCGGGGAGATTCTCGACCGCTCTGCGCTGAATGACGAACTGG
AGAAAATCGAGAAACCGGCTGGAATCAGCAATCCGAAGGACTTCCGCAACGAGGTGGTCAATTTCGTGTTGCGGGCGCGC
GCCAAGAACGAAGGCCGGAACCCGAGCTGGACTTCTTACGAAAAGCTGCGCGCCGTGATCGAGAAGAAGATGTTCTCGAA
CACCGAGGACCTGCTGCCGGTGATCAGCTTCAACGCCAAGGCCAGCGGGGACGAGCAGAAGAAGCACCAGGACTTCGTCA
ATCGCATGATCGAGAAGGGCTATACCGAAAAGCAGGTGCGTCTGTTGTGCGAGTGGTATCTCCGCGTCAGAAAGTCGTCG
TAA

Upstream 100 bases:

>100_bases
AGTGACCGCAGGCGGCTGGCGCCCGTCGGCCACGCTGCTCCGGAGTTTCGTACGCACCCGCTTCGGGTCCGAGCGACCCG
CCTTCGAAGGAGGTTTCCCG

Downstream 100 bases:

>100_bases
GCGTGCATGGCCCGGCCTGCCGCACCGCCCTGGTGCGGCAGTACCCCATCAGGAGGCGGCATGGTTCGCATCATCGACAG
GCGGTTCGACAGCAAGAACA

Product: PrkA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTIFNAYQARFEAAREEEMSIQEYLDLCKTDRSAYATAAERMLMAIGEPELVDTRLDPRLSRIFSNKVLKLYPAFRDFYG
MEEVIEHIVSYFRHAAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLIEKVPFYAIKGSPVHESPLGLFDVDEDGRILEDD
YGIPRRYLNTIMSPWAVKRLHEFNGDITRFRVIKLNPSVLRQIAVAKTEPGDENNQDISSLVGKIDIRMLEQFSQDDPDA
YSYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFDGIVMAHSNESEWVAFKNNKNNEAFLDRI
YTVKVPYCLRMSDEIRIYDKLLTHSSLSEAPCAPDTLKMMAQFSVLSRLKEPENSSIYSKMRVYDGENLKDTDPKAKSYQ
EYRDYAGVDEGMTGLSTRFAFKVLSKVFNFDHREVAANPVHLMYVLEQQIEQEQFMPETEARYMGFIKEYLAPRYAEFIG
KEIQTAYLESYSEYGQNIFDRYVIYADFWIQDQEFRDPNTGEILDRSALNDELEKIEKPAGISNPKDFRNEVVNFVLRAR
AKNEGRNPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAKASGDEQKKHQDFVNRMIEKGYTEKQVRLLCEWYLRVRKSS

Sequences:

>Translated_640_residues
MTIFNAYQARFEAAREEEMSIQEYLDLCKTDRSAYATAAERMLMAIGEPELVDTRLDPRLSRIFSNKVLKLYPAFRDFYG
MEEVIEHIVSYFRHAAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLIEKVPFYAIKGSPVHESPLGLFDVDEDGRILEDD
YGIPRRYLNTIMSPWAVKRLHEFNGDITRFRVIKLNPSVLRQIAVAKTEPGDENNQDISSLVGKIDIRMLEQFSQDDPDA
YSYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFDGIVMAHSNESEWVAFKNNKNNEAFLDRI
YTVKVPYCLRMSDEIRIYDKLLTHSSLSEAPCAPDTLKMMAQFSVLSRLKEPENSSIYSKMRVYDGENLKDTDPKAKSYQ
EYRDYAGVDEGMTGLSTRFAFKVLSKVFNFDHREVAANPVHLMYVLEQQIEQEQFMPETEARYMGFIKEYLAPRYAEFIG
KEIQTAYLESYSEYGQNIFDRYVIYADFWIQDQEFRDPNTGEILDRSALNDELEKIEKPAGISNPKDFRNEVVNFVLRAR
AKNEGRNPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAKASGDEQKKHQDFVNRMIEKGYTEKQVRLLCEWYLRVRKSS
>Mature_639_residues
TIFNAYQARFEAAREEEMSIQEYLDLCKTDRSAYATAAERMLMAIGEPELVDTRLDPRLSRIFSNKVLKLYPAFRDFYGM
EEVIEHIVSYFRHAAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLIEKVPFYAIKGSPVHESPLGLFDVDEDGRILEDDY
GIPRRYLNTIMSPWAVKRLHEFNGDITRFRVIKLNPSVLRQIAVAKTEPGDENNQDISSLVGKIDIRMLEQFSQDDPDAY
SYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFDGIVMAHSNESEWVAFKNNKNNEAFLDRIY
TVKVPYCLRMSDEIRIYDKLLTHSSLSEAPCAPDTLKMMAQFSVLSRLKEPENSSIYSKMRVYDGENLKDTDPKAKSYQE
YRDYAGVDEGMTGLSTRFAFKVLSKVFNFDHREVAANPVHLMYVLEQQIEQEQFMPETEARYMGFIKEYLAPRYAEFIGK
EIQTAYLESYSEYGQNIFDRYVIYADFWIQDQEFRDPNTGEILDRSALNDELEKIEKPAGISNPKDFRNEVVNFVLRARA
KNEGRNPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAKASGDEQKKHQDFVNRMIEKGYTEKQVRLLCEWYLRVRKSS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=644, Percent_Identity=77.0186335403727, Blast_Score=1065, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73781; Mature: 73649

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIFNAYQARFEAAREEEMSIQEYLDLCKTDRSAYATAAERMLMAIGEPELVDTRLDPRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SRIFSNKVLKLYPAFRDFYGMEEVIEHIVSYFRHAAQGLEEKKQILYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCHHHHH
EKLKSLIEKVPFYAIKGSPVHESPLGLFDVDEDGRILEDDYGIPRRYLNTIMSPWAVKRL
HHHHHHHHHCCEEEECCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCHHHHHHH
HEFNGDITRFRVIKLNPSVLRQIAVAKTEPGDENNQDISSLVGKIDIRMLEQFSQDDPDA
HHHCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YSYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFDGIVMAHSN
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESEWVAFKNNKNNEAFLDRIYTVKVPYCLRMSDEIRIYDKLLTHSSLSEAPCAPDTLKMM
CCCEEEEECCCCCHHHHHHHHHEECCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
AQFSVLSRLKEPENSSIYSKMRVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGLSTRFA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
FKVLSKVFNFDHREVAANPVHLMYVLEQQIEQEQFMPETEARYMGFIKEYLAPRYAEFIG
HHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVIYADFWIQDQEFRDPNTGEILDRSALNDELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GISNPKDFRNEVVNFVLRARAKNEGRNPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
ASGDEQKKHQDFVNRMIEKGYTEKQVRLLCEWYLRVRKSS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIFNAYQARFEAAREEEMSIQEYLDLCKTDRSAYATAAERMLMAIGEPELVDTRLDPRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SRIFSNKVLKLYPAFRDFYGMEEVIEHIVSYFRHAAQGLEEKKQILYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCHHHHH
EKLKSLIEKVPFYAIKGSPVHESPLGLFDVDEDGRILEDDYGIPRRYLNTIMSPWAVKRL
HHHHHHHHHCCEEEECCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCHHHHHHH
HEFNGDITRFRVIKLNPSVLRQIAVAKTEPGDENNQDISSLVGKIDIRMLEQFSQDDPDA
HHHCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YSYSGGLCLANRGLLEFVEMFKAPIKVLHPLLTATQEGNYKGTEGFGAIPFDGIVMAHSN
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESEWVAFKNNKNNEAFLDRIYTVKVPYCLRMSDEIRIYDKLLTHSSLSEAPCAPDTLKMM
CCCEEEEECCCCCHHHHHHHHHEECCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
AQFSVLSRLKEPENSSIYSKMRVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGLSTRFA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
FKVLSKVFNFDHREVAANPVHLMYVLEQQIEQEQFMPETEARYMGFIKEYLAPRYAEFIG
HHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVIYADFWIQDQEFRDPNTGEILDRSALNDELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GISNPKDFRNEVVNFVLRARAKNEGRNPSWTSYEKLRAVIEKKMFSNTEDLLPVISFNAK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
ASGDEQKKHQDFVNRMIEKGYTEKQVRLLCEWYLRVRKSS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]