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The map label for this gene is mhpD [H]

Identifier: 119898265

GI number: 119898265

Start: 2170617

End: 2171411

Strand: Reverse

Name: mhpD [H]

Synonym: azo1974

Alternate gene names: 119898265

Gene position: 2171411-2170617 (Counterclockwise)

Preceding gene: 119898266

Following gene: 119898264

Centisome position: 49.62

GC content: 70.19

Gene sequence:

>795_bases
ATGCCCCTCGAATCACCCGAAATCGCCGCAGCAGCAGAACTGCTGCACCGGGCCGCCAGCCAGCACCAGCCGATTGCGCC
GCTGCGCGAGCAGGTCGCCGATACCTCGGTGGAGGCCGCCTACGCGATCCAGGCGCACAACACGGCACGCGCGCTGGCCG
CGGGGCGCCGGCTGGTGGGCCGCAAGATCGGCCTGACCTCACCCGCCGTGCAGCGCCAGCTCGGCGTCGATCAGCCGGAC
TTCGGCATGCTGTTCGCCGACATGGCCGTAGGCGACGCCGAGCCGGTGGCGCGCGGCCGGCTGATCCAGCCCAAGGTGGA
GGCGGAAATCGCGTTCGTGCTCGGCCATCCGCTCGAACGCGAACGCCACACCTATGCCGACATCCTGCGCGCCATCGACT
TCTGCGTGCCGGCGGTCGAGATCGTCGACTCCCGCATCGCCGACTGGCGCATCAGCTTGTTCGACACCATCGCCGACAAC
GCCTCGTCCGGCCTCTTCGTGCTCGGCGGCAACCCGGTGCGGCCAGGCGCCTTCGACATCGGCCGCTGTGCGATGCGGAT
GAGCGAGGGCGAACGCGTGGTATCCGAAGGCAACGCCCGCGCCTGCCTCGGCAACCCGCTCAACGCCGCGGTGTGGCTGG
CCGACATGCTGGTCCGCGTCGGCCAGCCGCTGCAGGCCGGCGACATCGTGCTGACCGGTGCGCTCGGCCCGATGGTCGCG
GTCGATCCGCAGCGCCCCCAGCGTTTCCTCGTGGATATCGAAGGACTGGGCCACGTCGAGGCCTGCTTCGAATGA

Upstream 100 bases:

>100_bases
CCGCGCCATCCCCGAATGGCTGGCGGGCTTCGGCGCCATGTCGGGCCTTGGCCGCCACCCCTGATCGAACACACACATCA
CACACGGAGAGGACGTTCAG

Downstream 100 bases:

>100_bases
CCCCCGGGGCCGGGAGACGCAGACCTCCCGTCCGCCCCTGTACGACCCCAACCCCAGTGAGTGCAAGCATGAACAAGATC
AAATGCGCCTTGATTGGTCC

Product: MhpD protein

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase 1 [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPLESPEIAAAAELLHRAASQHQPIAPLREQVADTSVEAAYAIQAHNTARALAAGRRLVGRKIGLTSPAVQRQLGVDQPD
FGMLFADMAVGDAEPVARGRLIQPKVEAEIAFVLGHPLERERHTYADILRAIDFCVPAVEIVDSRIADWRISLFDTIADN
ASSGLFVLGGNPVRPGAFDIGRCAMRMSEGERVVSEGNARACLGNPLNAAVWLADMLVRVGQPLQAGDIVLTGALGPMVA
VDPQRPQRFLVDIEGLGHVEACFE

Sequences:

>Translated_264_residues
MPLESPEIAAAAELLHRAASQHQPIAPLREQVADTSVEAAYAIQAHNTARALAAGRRLVGRKIGLTSPAVQRQLGVDQPD
FGMLFADMAVGDAEPVARGRLIQPKVEAEIAFVLGHPLERERHTYADILRAIDFCVPAVEIVDSRIADWRISLFDTIADN
ASSGLFVLGGNPVRPGAFDIGRCAMRMSEGERVVSEGNARACLGNPLNAAVWLADMLVRVGQPLQAGDIVLTGALGPMVA
VDPQRPQRFLVDIEGLGHVEACFE
>Mature_263_residues
PLESPEIAAAAELLHRAASQHQPIAPLREQVADTSVEAAYAIQAHNTARALAAGRRLVGRKIGLTSPAVQRQLGVDQPDF
GMLFADMAVGDAEPVARGRLIQPKVEAEIAFVLGHPLERERHTYADILRAIDFCVPAVEIVDSRIADWRISLFDTIADNA
SSGLFVLGGNPVRPGAFDIGRCAMRMSEGERVVSEGNARACLGNPLNAAVWLADMLVRVGQPLQAGDIVLTGALGPMVAV
DPQRPQRFLVDIEGLGHVEACFE

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=249, Percent_Identity=53.4136546184739, Blast_Score=262, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 28279; Mature: 28148

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLESPEIAAAAELLHRAASQHQPIAPLREQVADTSVEAAYAIQAHNTARALAAGRRLVG
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHH
RKIGLTSPAVQRQLGVDQPDFGMLFADMAVGDAEPVARGRLIQPKVEAEIAFVLGHPLER
HHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHEEEEEECCCCCH
ERHTYADILRAIDFCVPAVEIVDSRIADWRISLFDTIADNASSGLFVLGGNPVRPGAFDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHH
GRCAMRMSEGERVVSEGNARACLGNPLNAAVWLADMLVRVGQPLQAGDIVLTGALGPMVA
HHHHHHHHCCCHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
VDPQRPQRFLVDIEGLGHVEACFE
ECCCCCCEEEEEECCCCCHHHHCC
>Mature Secondary Structure 
PLESPEIAAAAELLHRAASQHQPIAPLREQVADTSVEAAYAIQAHNTARALAAGRRLVG
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHH
RKIGLTSPAVQRQLGVDQPDFGMLFADMAVGDAEPVARGRLIQPKVEAEIAFVLGHPLER
HHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHEEEEEECCCCCH
ERHTYADILRAIDFCVPAVEIVDSRIADWRISLFDTIADNASSGLFVLGGNPVRPGAFDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHH
GRCAMRMSEGERVVSEGNARACLGNPLNAAVWLADMLVRVGQPLQAGDIVLTGALGPMVA
HHHHHHHHCCCHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
VDPQRPQRFLVDIEGLGHVEACFE
ECCCCCCEEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA