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The map label for this gene is dctD2 [H]

Identifier: 119898205

GI number: 119898205

Start: 2099467

End: 2100810

Strand: Reverse

Name: dctD2 [H]

Synonym: azo1914

Alternate gene names: 119898205

Gene position: 2100810-2099467 (Counterclockwise)

Preceding gene: 119898206

Following gene: 119898203

Centisome position: 48.01

GC content: 70.01

Gene sequence:

>1344_bases
ATGACTGCAATCCCGCTCCGCGTGCTCTACGTGGAGGACGATGAGGCGGTACGCATGGCCGGCTGCCAGACTTTTGCGCT
GGCCGATCTCGCGGTCGAAGGCGTCGATCGCGCCGAGGCGGCGCTGCCCAGCCTTGCCTCCGACGCGCCGCTGGTGCTGG
TAACCGACGTGCGGCTGCCCGGCATGGACGGCATGGGCCTGCTGCGCCGCGCGATGGAGATCGATCCCGACCTGCCGGTG
ATCCTGGTCACCGGCCATGGCGACGTCGCGATGGCGGTGGAGGCGATGCGGGCAGGCGCCTACGACTTCATCGAGAAACC
CTTCGCCCCCGAGGCGATGGTGGAGGTGGTGCGGCGCGCCCTGGAAAAACGCCAGCTGGTGCTGGAAAACCGCGCGCTCA
AGGCCCGTCTGGCCGAAGACATCGCCATCGAGGGGCTGCTGGGCGACAGCGCGCCGATGCAGCAGGTGCGCACGCTGATC
GCCGAACTGGCCGACACCGACGTGGATGTGCTGGTGCTGGGCGAAACCGGAACCGGCAAGGAGAAGGTGGCGCGCGGGCT
GCACGAGGCCGGCCGCCGCCGCAGCGGCAACTTCGTCGCGATCAACTGCGCCGCGCTGCCGGAAAGCGTGTTCGAAAGCG
AGATGTTCGGCGTGGAGCCGGGTGCCTATACCGGCGCAACCCGCAGCCGCGCCGGCAAGATCGAACACGCCACCGGCGGC
ACCTTGTTCCTCGACGAGATCGAGGGCATGCCGCTGGCGCTGCAGGCCAAGCTGCTGCGCGTGCTGCAGGAGCGCGTGGT
GGAGCGCCTGGGGTCGAACCGGCTGATACCGGTGGACTGCCGCATCGTCGCCGCGACCAAGGTGGACCTGAAGGCCGAGA
GCGAAGCCGGACGCTTTCGTGCCGACCTGTACTACCGCCTGAACGTGGTGACCGTGGCGCTGCCGCCGCTGCGCGAGCGG
CGCGAAGACATTCCGCGCCTGTTCCAGGCCTTCTGCCTGCGCGCCGCGGAACGCTACCGGCGACCGCCGCCCGTCATCGA
CACCGTGCTGGCCGACTGGCTGATGAGCGCGGACTGGCCCGGCAATGTGCGCGAGCTGCTGCACGCGGCCGAACGCCACA
CGCTGGGCCTGTGGCAGCCGCTTGCGGAGACGCCGGCGGAAGCCGGGCGGACGATGCCGCAGCGCATTGCTGCCTTCGAG
CAGTTCCTGATCGAAAGCGCGCTGGCCGAAACCGGCGGCGACGTTGCTGCCGCGGCGCTGACGCTGGGGGTGCCGCGCAA
GACGCTGTACGACAAGCTCGCGCGCCTGAACCTGCCGCCGCGCCGCTTCCGTCTCGTGCAGTAG

Upstream 100 bases:

>100_bases
GCTTCGGGCGGTAGCCTCGACATCGGCGCATCCGACGCCGGCGGGGCGCGAATCCGCGCGTACTGGGCCCGGCCCGCCAC
GCGCGCCTAGGAGGAGACGA

Downstream 100 bases:

>100_bases
GGTTCAGCCGCGGCCGGCGTCGGCCAGCATCTGCTGCGCCACGGCCTCGGCCACGCGGATGCCATCCACGCCGGCCGACA
GGATGCCCCCCGCGTAGCCC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTAIPLRVLYVEDDEAVRMAGCQTFALADLAVEGVDRAEAALPSLASDAPLVLVTDVRLPGMDGMGLLRRAMEIDPDLPV
ILVTGHGDVAMAVEAMRAGAYDFIEKPFAPEAMVEVVRRALEKRQLVLENRALKARLAEDIAIEGLLGDSAPMQQVRTLI
AELADTDVDVLVLGETGTGKEKVARGLHEAGRRRSGNFVAINCAALPESVFESEMFGVEPGAYTGATRSRAGKIEHATGG
TLFLDEIEGMPLALQAKLLRVLQERVVERLGSNRLIPVDCRIVAATKVDLKAESEAGRFRADLYYRLNVVTVALPPLRER
REDIPRLFQAFCLRAAERYRRPPPVIDTVLADWLMSADWPGNVRELLHAAERHTLGLWQPLAETPAEAGRTMPQRIAAFE
QFLIESALAETGGDVAAAALTLGVPRKTLYDKLARLNLPPRRFRLVQ

Sequences:

>Translated_447_residues
MTAIPLRVLYVEDDEAVRMAGCQTFALADLAVEGVDRAEAALPSLASDAPLVLVTDVRLPGMDGMGLLRRAMEIDPDLPV
ILVTGHGDVAMAVEAMRAGAYDFIEKPFAPEAMVEVVRRALEKRQLVLENRALKARLAEDIAIEGLLGDSAPMQQVRTLI
AELADTDVDVLVLGETGTGKEKVARGLHEAGRRRSGNFVAINCAALPESVFESEMFGVEPGAYTGATRSRAGKIEHATGG
TLFLDEIEGMPLALQAKLLRVLQERVVERLGSNRLIPVDCRIVAATKVDLKAESEAGRFRADLYYRLNVVTVALPPLRER
REDIPRLFQAFCLRAAERYRRPPPVIDTVLADWLMSADWPGNVRELLHAAERHTLGLWQPLAETPAEAGRTMPQRIAAFE
QFLIESALAETGGDVAAAALTLGVPRKTLYDKLARLNLPPRRFRLVQ
>Mature_446_residues
TAIPLRVLYVEDDEAVRMAGCQTFALADLAVEGVDRAEAALPSLASDAPLVLVTDVRLPGMDGMGLLRRAMEIDPDLPVI
LVTGHGDVAMAVEAMRAGAYDFIEKPFAPEAMVEVVRRALEKRQLVLENRALKARLAEDIAIEGLLGDSAPMQQVRTLIA
ELADTDVDVLVLGETGTGKEKVARGLHEAGRRRSGNFVAINCAALPESVFESEMFGVEPGAYTGATRSRAGKIEHATGGT
LFLDEIEGMPLALQAKLLRVLQERVVERLGSNRLIPVDCRIVAATKVDLKAESEAGRFRADLYYRLNVVTVALPPLRERR
EDIPRLFQAFCLRAAERYRRPPPVIDTVLADWLMSADWPGNVRELLHAAERHTLGLWQPLAETPAEAGRTMPQRIAAFEQ
FLIESALAETGGDVAAAALTLGVPRKTLYDKLARLNLPPRRFRLVQ

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=459, Percent_Identity=39.6514161220044, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI1790437, Length=396, Percent_Identity=42.4242424242424, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=37.4732334047109, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1788905, Length=453, Percent_Identity=37.9690949227373, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=352, Percent_Identity=41.4772727272727, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789087, Length=335, Percent_Identity=44.4776119402985, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=50.2202643171806, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1789233, Length=230, Percent_Identity=46.9565217391304, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1786524, Length=318, Percent_Identity=41.5094339622642, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=42.6086956521739, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787583, Length=250, Percent_Identity=38, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI87081858, Length=308, Percent_Identity=31.8181818181818, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789828, Length=212, Percent_Identity=39.1509433962264, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48918; Mature: 48787

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIPLRVLYVEDDEAVRMAGCQTFALADLAVEGVDRAEAALPSLASDAPLVLVTDVRLP
CCCCEEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCC
GMDGMGLLRRAMEIDPDLPVILVTGHGDVAMAVEAMRAGAYDFIEKPFAPEAMVEVVRRA
CCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
LEKRQLVLENRALKARLAEDIAIEGLLGDSAPMQQVRTLIAELADTDVDVLVLGETGTGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCH
EKVARGLHEAGRRRSGNFVAINCAALPESVFESEMFGVEPGAYTGATRSRAGKIEHATGG
HHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCHHHCCCCEECCCC
TLFLDEIEGMPLALQAKLLRVLQERVVERLGSNRLIPVDCRIVAATKVDLKAESEAGRFR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEEEEEEEECCCCCCCCCEE
ADLYYRLNVVTVALPPLRERREDIPRLFQAFCLRAAERYRRPPPVIDTVLADWLMSADWP
EEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
GNVRELLHAAERHTLGLWQPLAETPAEAGRTMPQRIAAFEQFLIESALAETGGDVAAAAL
CHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TLGVPRKTLYDKLARLNLPPRRFRLVQ
HHCCCHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
TAIPLRVLYVEDDEAVRMAGCQTFALADLAVEGVDRAEAALPSLASDAPLVLVTDVRLP
CCCEEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCC
GMDGMGLLRRAMEIDPDLPVILVTGHGDVAMAVEAMRAGAYDFIEKPFAPEAMVEVVRRA
CCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
LEKRQLVLENRALKARLAEDIAIEGLLGDSAPMQQVRTLIAELADTDVDVLVLGETGTGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCH
EKVARGLHEAGRRRSGNFVAINCAALPESVFESEMFGVEPGAYTGATRSRAGKIEHATGG
HHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCHHHCCCCEECCCC
TLFLDEIEGMPLALQAKLLRVLQERVVERLGSNRLIPVDCRIVAATKVDLKAESEAGRFR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEEEEEEEECCCCCCCCCEE
ADLYYRLNVVTVALPPLRERREDIPRLFQAFCLRAAERYRRPPPVIDTVLADWLMSADWP
EEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
GNVRELLHAAERHTLGLWQPLAETPAEAGRTMPQRIAAFEQFLIESALAETGGDVAAAAL
CHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TLGVPRKTLYDKLARLNLPPRRFRLVQ
HHCCCHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]