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The map label for this gene is frr

Identifier: 119898197

GI number: 119898197

Start: 2090246

End: 2090803

Strand: Reverse

Name: frr

Synonym: azo1906

Alternate gene names: 119898197

Gene position: 2090803-2090246 (Counterclockwise)

Preceding gene: 119898198

Following gene: 119898196

Centisome position: 47.78

GC content: 61.29

Gene sequence:

>558_bases
ATGATTTCCGATCTCAAGAAGACGACTGAGCAGAAGATGCAGAAGTCGATCGACGCGCTGAAGACCGACCTCGCCAAGAT
CCGCACCGGCCGTGCCCACACCGGTCTGCTCGATCACGTGATGGTCGAGTACTACGGCTCCATGGTGCCGATCAACCAAG
TCGCCAACATCACCCTGATCGACGCCCGCACCATCGGCGTCCAGACCTGGGAAAAGCCCATGCTCGGCAAGGTCGAGAAG
GCCATCCGCGACTGCGACCTCGGTCTCAACCCCGCCAACATGGGCGAGATCATCCGCGTGCCGATGCCGGCGCTCACCGA
AGAGCGCCGCCGCGACCTCACCAAGGTGGTCCGCCAGGAAGGCGAAACCGCCAAGGTCGCAGTCCGCAACCTGCGCCGCG
ATGCCAACCAGCATCTGAAAGACGCGGTGAAGGACAAGACCATCTCCGAGGACGACGAGCGTCGCTCCCAGGATGACATC
CAGAAGCTGACCGACAAGTACGTCGCCGAAATCGACAAGCTGCTCGCCCAGAAAGAGCAGGAACTGATGCAGATCTGA

Upstream 100 bases:

>100_bases
CTGCCGATCAACGTGTTCTCGATCTTCAAGCCCGGCGCGCTCAAGCGTGTCGTGATGGGTGAAGACGAAGGGACGCTGGT
CCATTCCTGAGGAGTCGCGC

Downstream 100 bases:

>100_bases
TCTCCGGATCGACTGTTCCCAGAGCGGACGAGGCGAGGAGGCGGACGATGGCCGATATCGGCTTTACCAGTTCGACCCGG
GCGATCCCCGAGGTCAGCAC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLIDARTIGVQTWEKPMLGKVEK
AIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQEGETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDI
QKLTDKYVAEIDKLLAQKEQELMQI

Sequences:

>Translated_185_residues
MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLIDARTIGVQTWEKPMLGKVEK
AIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQEGETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDI
QKLTDKYVAEIDKLLAQKEQELMQI
>Mature_185_residues
MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLIDARTIGVQTWEKPMLGKVEK
AIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQEGETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDI
QKLTDKYVAEIDKLLAQKEQELMQI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=183, Percent_Identity=34.4262295081967, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=35.3333333333333, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=56.7567567567568, Blast_Score=216, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=28.9017341040462, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_AZOSB (A1K6R8)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_933410.1
- ProteinModelPortal:   A1K6R8
- SMR:   A1K6R8
- STRING:   A1K6R8
- GeneID:   4610070
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo1906
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1K6R8
- ProtClustDB:   PRK00083
- BioCyc:   ASP62928:AZO1906-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21094; Mature: 21094

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEE
DARTIGVQTWEKPMLGKVEKAIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQE
CCHHHCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDIQKLTDKYVAEIDKLLAQKEQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMQI
HHHCC
>Mature Secondary Structure
MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEE
DARTIGVQTWEKPMLGKVEKAIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQE
CCHHHCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDIQKLTDKYVAEIDKLLAQKEQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMQI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA