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The map label for this gene is fabZ [H]

Identifier: 119898189

GI number: 119898189

Start: 2081667

End: 2082104

Strand: Reverse

Name: fabZ [H]

Synonym: azo1898

Alternate gene names: 119898189

Gene position: 2082104-2081667 (Counterclockwise)

Preceding gene: 119898190

Following gene: 119898188

Centisome position: 47.58

GC content: 59.13

Gene sequence:

>438_bases
ATGGATATCAACGAAATCGTCCAATACCTCCCACACCGTTACCCCTTCCTGCTGGTGGATCGGGTGCTGGAGCTGGAAGA
GAACAAGCGCATCCTCGCGCTGAAGAACGTGACGATGAACGAACCGTTCTTCCCGGGCCATTTCCCGCATCACCCGGTGA
TGCCCGGCGTCCTCATCGTCGAGGCAATGGCTCAGGCCGCCGCGGTGCTGTCGTTCAAGAGCATGGGCGTGAAGCCCGAC
CAGAATTCGGTCGTTTACTTCGCGGGCATCGACGCCGTGCGCTTCAAGCGCCCGGTGGTACCGGGGGACCAGTTGCTGAT
GGAAGTCGAGATCACCCAGAGCAAGCGCAACATCTACAAGTACAAGGGCGTAGCGCGCGTGAATGGTGAAATCGCGACCG
AAGCCGAACTGATGTGCGCACTCAAGACCCTGTCATGA

Upstream 100 bases:

>100_bases
GGGTGAAAAACTTCGCCCACCTGCGCCACCTGGACAGCCTCGCCGCTAGAATACGCGCCCTCGAACAATCGCCGGACCAC
CCGGAATCAGCCTGATCGCC

Downstream 100 bases:

>100_bases
TCCACCCGACCGCCATCATTCACCCCGGCGCACGGCTGGGCGCCAATGTTGCCGTCGGTGCGTATTCCATCATCGGCGAA
CACGTCGAGATCGGCGACGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDINEIVQYLPHRYPFLLVDRVLELEENKRILALKNVTMNEPFFPGHFPHHPVMPGVLIVEAMAQAAAVLSFKSMGVKPD
QNSVVYFAGIDAVRFKRPVVPGDQLLMEVEITQSKRNIYKYKGVARVNGEIATEAELMCALKTLS

Sequences:

>Translated_145_residues
MDINEIVQYLPHRYPFLLVDRVLELEENKRILALKNVTMNEPFFPGHFPHHPVMPGVLIVEAMAQAAAVLSFKSMGVKPD
QNSVVYFAGIDAVRFKRPVVPGDQLLMEVEITQSKRNIYKYKGVARVNGEIATEAELMCALKTLS
>Mature_145_residues
MDINEIVQYLPHRYPFLLVDRVLELEENKRILALKNVTMNEPFFPGHFPHHPVMPGVLIVEAMAQAAAVLSFKSMGVKPD
QNSVVYFAGIDAVRFKRPVVPGDQLLMEVEITQSKRNIYKYKGVARVNGEIATEAELMCALKTLS

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=57.8571428571429, Blast_Score=179, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16354; Mature: 16354

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINEIVQYLPHRYPFLLVDRVLELEENKRILALKNVTMNEPFFPGHFPHHPVMPGVLIV
CCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
EAMAQAAAVLSFKSMGVKPDQNSVVYFAGIDAVRFKRPVVPGDQLLMEVEITQSKRNIYK
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEEEECCCHHHHHH
YKGVARVNGEIATEAELMCALKTLS
HCCEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDINEIVQYLPHRYPFLLVDRVLELEENKRILALKNVTMNEPFFPGHFPHHPVMPGVLIV
CCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
EAMAQAAAVLSFKSMGVKPDQNSVVYFAGIDAVRFKRPVVPGDQLLMEVEITQSKRNIYK
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEEEECCCHHHHHH
YKGVARVNGEIATEAELMCALKTLS
HCCEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA