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The map label for this gene is gmhB1 [H]

Identifier: 119898098

GI number: 119898098

Start: 1984769

End: 1985425

Strand: Reverse

Name: gmhB1 [H]

Synonym: azo1807

Alternate gene names: 119898098

Gene position: 1985425-1984769 (Counterclockwise)

Preceding gene: 119898099

Following gene: 119898097

Centisome position: 45.37

GC content: 73.36

Gene sequence:

>657_bases
GTGGCCCTGAGCCGCGCATGCGACCCGCCCGCCGACGCGCGCGGGCGGGGTGCGCCGGCCGTCTTCCTCGACAAGGACGG
CACGCTGCTGCATGACGTGCCCTACAACGTCGACCCGGCCCGCCTGCGCCTGCGCGCGGACGCCGGGCCGGCGCTGGCGC
TGCTGCGGCGCAACGGCTATCGCCTGGTGCTGGTCTCCAACCAGGCCGGCGTCGCGCTCGGGCGTTTCGACGAGGCGGCG
CTGCCGCCCCTGTGGCGTGCGTTGGGCGAAGCGCTGGCCCCCTGGGGTGTGGCGCTGGACGGCGTCTATTACTGCCCGCA
TCACCCCAAGGGCTGCGTGCCGGCCTATACGCGCCACTGCGACTGCCGCAAACCCGCGCCCGGCCTGCTGCAGCGCGCGG
CGCTGGAACTCGGGCTGGACCTCGCCCGCAGCTGGTTCATCGGCGACATCCTCGATGACGTCGAGGCTGGCCGCCGCGCC
GGCTGCCGCACCGTGCTGCTCGACGTGGGCTCGGAAACCGAGTGGATCAGCACGCCGATGCGCCATCCGGACCACGTTGT
CGCCAGCCTCACCGAGGCGGCGTTTACCCTCCTTGCCGATGAAGCCTTGCGGGTCGCGCCGGAAGGCGTCGCGGAGCAGC
CGCAATGGACCGGGTGA

Upstream 100 bases:

>100_bases
AGCCGCCCGAGTCGGTGGCCAATGCGGTGCTGCAGGTGCTGCAGATGCCGGCGGGCAGCGTGGTGCCGGAGATCTCGGTG
CTGCCGATGGGAGAGACCTC

Downstream 100 bases:

>100_bases
GCTTGCTGCGGCGCCAGCCCGCGCGGGGACAGGCCGCGGCGGACGGCGCGCCGCTCACCGTGGTGCCGCCGCTGCCGGAA
GCCGCGCCCGCCACCGCGGC

Product: heptose phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase 1 [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MALSRACDPPADARGRGAPAVFLDKDGTLLHDVPYNVDPARLRLRADAGPALALLRRNGYRLVLVSNQAGVALGRFDEAA
LPPLWRALGEALAPWGVALDGVYYCPHHPKGCVPAYTRHCDCRKPAPGLLQRAALELGLDLARSWFIGDILDDVEAGRRA
GCRTVLLDVGSETEWISTPMRHPDHVVASLTEAAFTLLADEALRVAPEGVAEQPQWTG

Sequences:

>Translated_218_residues
MALSRACDPPADARGRGAPAVFLDKDGTLLHDVPYNVDPARLRLRADAGPALALLRRNGYRLVLVSNQAGVALGRFDEAA
LPPLWRALGEALAPWGVALDGVYYCPHHPKGCVPAYTRHCDCRKPAPGLLQRAALELGLDLARSWFIGDILDDVEAGRRA
GCRTVLLDVGSETEWISTPMRHPDHVVASLTEAAFTLLADEALRVAPEGVAEQPQWTG
>Mature_217_residues
ALSRACDPPADARGRGAPAVFLDKDGTLLHDVPYNVDPARLRLRADAGPALALLRRNGYRLVLVSNQAGVALGRFDEAAL
PPLWRALGEALAPWGVALDGVYYCPHHPKGCVPAYTRHCDCRKPAPGLLQRAALELGLDLARSWFIGDILDDVEAGRRAG
CRTVLLDVGSETEWISTPMRHPDHVVASLTEAAFTLLADEALRVAPEGVAEQPQWTG

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=152, Percent_Identity=40.7894736842105, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082027, Length=144, Percent_Identity=32.6388888888889, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 23498; Mature: 23367

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSRACDPPADARGRGAPAVFLDKDGTLLHDVPYNVDPARLRLRADAGPALALLRRNGY
CCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHEEEECCCCHHHHEEECCCC
RLVLVSNQAGVALGRFDEAALPPLWRALGEALAPWGVALDGVYYCPHHPKGCVPAYTRHC
EEEEEECCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEECCEEECCCCCCCCCCHHHCCC
DCRKPAPGLLQRAALELGLDLARSWFIGDILDDVEAGRRAGCRTVLLDVGSETEWISTPM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCC
RHPDHVVASLTEAAFTLLADEALRVAPEGVAEQPQWTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ALSRACDPPADARGRGAPAVFLDKDGTLLHDVPYNVDPARLRLRADAGPALALLRRNGY
CCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHEEEECCCCHHHHEEECCCC
RLVLVSNQAGVALGRFDEAALPPLWRALGEALAPWGVALDGVYYCPHHPKGCVPAYTRHC
EEEEEECCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEECCEEECCCCCCCCCCHHHCCC
DCRKPAPGLLQRAALELGLDLARSWFIGDILDDVEAGRRAGCRTVLLDVGSETEWISTPM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCC
RHPDHVVASLTEAAFTLLADEALRVAPEGVAEQPQWTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]