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The map label for this gene is era [H]

Identifier: 119897934

GI number: 119897934

Start: 1803203

End: 1804117

Strand: Direct

Name: era [H]

Synonym: azo1643

Alternate gene names: 119897934

Gene position: 1803203-1804117 (Clockwise)

Preceding gene: 119897933

Following gene: 119897935

Centisome position: 41.21

GC content: 63.72

Gene sequence:

>915_bases
ATGAACATCGAAGAAGCGGTCCCTTCCGCAAAGCCGGGCTTCAGGACCGGTTTTGTGGCCATCGTCGGACGGCCCAACGT
CGGCAAGTCGACGCTGCTCAACCGCTTGATCGGTCAGAAGATCAGCATCGTCTCCAGCAAGGCCCAGACTACCCGCCACC
GCGTCACCGGCATCCTGACCAATGAGGGCGCGCAGTTCGTCTTCGTCGATACGCCGGGCTTCCAGACCCAGCACCGCAAC
GCGCTCAACCGCTCGATGAACCGCACGGTGTCGCAGGTGCTGGGCGATGTCGACCTGGTCTTCTTCGTGATAGAGGCGGG
CCGCTTCGGCGAGGACGATCGCAAGGTGCTGGAGGTGATTCCGGCCGATGCGCAGGTGGTGCTGGTGATCAACAAGGTCG
ATCAGCTGAAGGACAAAAGCCGGCTGCTGCCTTTCATCGACCAGGTGCGCGCCGCGCGCGAATTCGTCGAGATCGTGCCG
CTGTCGGCCGAGCGCGGCAGCAACGTCGAGGCGCTGGTGGGGGCGGCGACGCCGCTGTTGCCGGAAGGTGCGCCGATGTA
CGAGGAAGACGAGATCACCGACCGCAGCGAGCGCTTCCTTGCCGCCGAATTCCTGCGCGAGAAGCTGTTCCGGCTGCTCG
GCGATGAGTTGCCGTATGGCATTGCGGTGGAAATCGAGAAGTTCGAGACCGAAGGCAACCTGCGTCGCATCCACGCCGCG
GTGATCGTCGACAAGGCGGGCCACAAGGGCATCGTCATCGGCAAGGGCGGCGAGAAGCTCAAGCGGGTTTCGACCGAGGC
CCGCGTCGAACTCGAGAAGCTCTTCGACGGCAAGGTTTTCCTCGAGGTGTGGGTCAAGGTCAAGAGCGGCTGGGCGGACG
ACGAACGCGCGCTGAAGAGCCTCGGCTACGAGTAA

Upstream 100 bases:

>100_bases
AAGTCGAAAAGCACAAGGTGCGCACCGTGGGGCGCGGTACCAGCCGCCGGATTGCCGAGCAGCGCGCCGCCGAACTCGCG
CTTGCCCAGTTGAGGAAGAA

Downstream 100 bases:

>100_bases
GCGCCGGAGCGGGGACGGCACGCGGTGGCGGTCAAGCAGCGCATCGACCAACAGTCGGCCTGGGTGCTGCACACGCTGCC
GTGGCGCGAAACCAGCCTGA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNIEEAVPSAKPGFRTGFVAIVGRPNVGKSTLLNRLIGQKISIVSSKAQTTRHRVTGILTNEGAQFVFVDTPGFQTQHRN
ALNRSMNRTVSQVLGDVDLVFFVIEAGRFGEDDRKVLEVIPADAQVVLVINKVDQLKDKSRLLPFIDQVRAAREFVEIVP
LSAERGSNVEALVGAATPLLPEGAPMYEEDEITDRSERFLAAEFLREKLFRLLGDELPYGIAVEIEKFETEGNLRRIHAA
VIVDKAGHKGIVIGKGGEKLKRVSTEARVELEKLFDGKVFLEVWVKVKSGWADDERALKSLGYE

Sequences:

>Translated_304_residues
MNIEEAVPSAKPGFRTGFVAIVGRPNVGKSTLLNRLIGQKISIVSSKAQTTRHRVTGILTNEGAQFVFVDTPGFQTQHRN
ALNRSMNRTVSQVLGDVDLVFFVIEAGRFGEDDRKVLEVIPADAQVVLVINKVDQLKDKSRLLPFIDQVRAAREFVEIVP
LSAERGSNVEALVGAATPLLPEGAPMYEEDEITDRSERFLAAEFLREKLFRLLGDELPYGIAVEIEKFETEGNLRRIHAA
VIVDKAGHKGIVIGKGGEKLKRVSTEARVELEKLFDGKVFLEVWVKVKSGWADDERALKSLGYE
>Mature_304_residues
MNIEEAVPSAKPGFRTGFVAIVGRPNVGKSTLLNRLIGQKISIVSSKAQTTRHRVTGILTNEGAQFVFVDTPGFQTQHRN
ALNRSMNRTVSQVLGDVDLVFFVIEAGRFGEDDRKVLEVIPADAQVVLVINKVDQLKDKSRLLPFIDQVRAAREFVEIVP
LSAERGSNVEALVGAATPLLPEGAPMYEEDEITDRSERFLAAEFLREKLFRLLGDELPYGIAVEIEKFETEGNLRRIHAA
VIVDKAGHKGIVIGKGGEKLKRVSTEARVELEKLFDGKVFLEVWVKVKSGWADDERALKSLGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=26.5625, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788919, Length=290, Percent_Identity=51.3793103448276, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI87082120, Length=184, Percent_Identity=29.8913043478261, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532761, Length=149, Percent_Identity=32.2147651006711, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646434, Length=317, Percent_Identity=28.391167192429, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33707; Mature: 33707

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEEAVPSAKPGFRTGFVAIVGRPNVGKSTLLNRLIGQKISIVSSKAQTTRHRVTGILT
CCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEE
NEGAQFVFVDTPGFQTQHRNALNRSMNRTVSQVLGDVDLVFFVIEAGRFGEDDRKVLEVI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCHHHHHHHHC
PADAQVVLVINKVDQLKDKSRLLPFIDQVRAAREFVEIVPLSAERGSNVEALVGAATPLL
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHCCCCCC
PEGAPMYEEDEITDRSERFLAAEFLREKLFRLLGDELPYGIAVEIEKFETEGNLRRIHAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEE
VIVDKAGHKGIVIGKGGEKLKRVSTEARVELEKLFDGKVFLEVWVKVKSGWADDERALKS
EEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHEEHHHHCCCCCHHHHHHH
LGYE
CCCC
>Mature Secondary Structure
MNIEEAVPSAKPGFRTGFVAIVGRPNVGKSTLLNRLIGQKISIVSSKAQTTRHRVTGILT
CCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEE
NEGAQFVFVDTPGFQTQHRNALNRSMNRTVSQVLGDVDLVFFVIEAGRFGEDDRKVLEVI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCHHHHHHHHC
PADAQVVLVINKVDQLKDKSRLLPFIDQVRAAREFVEIVPLSAERGSNVEALVGAATPLL
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHCCCCCC
PEGAPMYEEDEITDRSERFLAAEFLREKLFRLLGDELPYGIAVEIEKFETEGNLRRIHAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEE
VIVDKAGHKGIVIGKGGEKLKRVSTEARVELEKLFDGKVFLEVWVKVKSGWADDERALKS
EEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHEEHHHHCCCCCHHHHHHH
LGYE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA