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The map label for this gene is ptpA [C]

Identifier: 119897903

GI number: 119897903

Start: 1775724

End: 1776188

Strand: Direct

Name: ptpA [C]

Synonym: azo1612

Alternate gene names: 119897903

Gene position: 1775724-1776188 (Clockwise)

Preceding gene: 119897902

Following gene: 119897905

Centisome position: 40.58

GC content: 65.16

Gene sequence:

>465_bases
GTGAAGCGCGTTCTATTCGTTTGCACCGGCAACATCTGCAGGTCGCCCACGGCCGAAGGGGTTGCGCTGCACATGATCCA
CAGTGGCGGCCTCGGCGCCCATGTTCATGTGGATTCCGCGGGCACTCACGGCTACCACGTGGGCGAGGCGCCGGATCCGC
GTACGCTCAAGGCGGCGGCCCGACGTGGCTACGATCTCAGTCCCTTGCGGGCGCGCAAGCTGGAACTGCGCGATTTCCAG
GATTTCGACCTGCTGCTGGCAATGGATCGCGGCCACCTCGACCTGATGAAGCGGGCGTGCCCGGAGGTGTATCGGCCCAA
GCTCGATCTGTTCCTGCGCTACGCCGCGAAAACCGGGTTCGATGAGGTGCCGGACCCGTATTACGGCGGTCCGCAGGGTT
TCGAGATGGTGCTCGACATGTGCGAGGCTGGCGTCGACGGCCTGCTGGATCGGATCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCTGGAGTTCGAAAAGGCCGCGGCCGCGCGCGACGAACTGTTCAAGCTGCGAGAACGCGCTTTTGGCGCGGACCAGCACG
GCAATACCTAGGGAGGAGTG

Downstream 100 bases:

>100_bases
CGGGAATGGGCGCGCACGCGCCCCGGTCGTCAGCGCCGACCAGAACGAAAAAAGGCCACCTTGCGGTGGCCTTTTTTCTG
GACGCGGTCTGCGCTTACTT

Product: PtpA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKRVLFVCTGNICRSPTAEGVALHMIHSGGLGAHVHVDSAGTHGYHVGEAPDPRTLKAAARRGYDLSPLRARKLELRDFQ
DFDLLLAMDRGHLDLMKRACPEVYRPKLDLFLRYAAKTGFDEVPDPYYGGPQGFEMVLDMCEAGVDGLLDRIGA

Sequences:

>Translated_154_residues
MKRVLFVCTGNICRSPTAEGVALHMIHSGGLGAHVHVDSAGTHGYHVGEAPDPRTLKAAARRGYDLSPLRARKLELRDFQ
DFDLLLAMDRGHLDLMKRACPEVYRPKLDLFLRYAAKTGFDEVPDPYYGGPQGFEMVLDMCEAGVDGLLDRIGA
>Mature_154_residues
MKRVLFVCTGNICRSPTAEGVALHMIHSGGLGAHVHVDSAGTHGYHVGEAPDPRTLKAAARRGYDLSPLRARKLELRDFQ
DFDLLLAMDRGHLDLMKRACPEVYRPKLDLFLRYAAKTGFDEVPDPYYGGPQGFEMVLDMCEAGVDGLLDRIGA

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=152, Percent_Identity=36.1842105263158, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI6005988, Length=152, Percent_Identity=32.8947368421053, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788375, Length=139, Percent_Identity=35.2517985611511, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081812, Length=150, Percent_Identity=34.6666666666667, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=135, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78706770, Length=149, Percent_Identity=35.5704697986577, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706772, Length=149, Percent_Identity=35.5704697986577, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706766, Length=142, Percent_Identity=31.6901408450704, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706768, Length=142, Percent_Identity=31.6901408450704, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=31.25, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78711846, Length=148, Percent_Identity=33.1081081081081, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16970; Mature: 16970

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLFVCTGNICRSPTAEGVALHMIHSGGLGAHVHVDSAGTHGYHVGEAPDPRTLKAAA
CCEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCCCHHHHHHH
RRGYDLSPLRARKLELRDFQDFDLLLAMDRGHLDLMKRACPEVYRPKLDLFLRYAAKTGF
HCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCHHHHCCHHHHHHHHHHHCCC
DEVPDPYYGGPQGFEMVLDMCEAGVDGLLDRIGA
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MKRVLFVCTGNICRSPTAEGVALHMIHSGGLGAHVHVDSAGTHGYHVGEAPDPRTLKAAA
CCEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCCCHHHHHHH
RRGYDLSPLRARKLELRDFQDFDLLLAMDRGHLDLMKRACPEVYRPKLDLFLRYAAKTGF
HCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCHHHHCCHHHHHHHHHHHCCC
DEVPDPYYGGPQGFEMVLDMCEAGVDGLLDRIGA
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]