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The map label for this gene is moxY [H]

Identifier: 119897795

GI number: 119897795

Start: 1644737

End: 1646212

Strand: Reverse

Name: moxY [H]

Synonym: azo1504

Alternate gene names: 119897795

Gene position: 1646212-1644737 (Counterclockwise)

Preceding gene: 119897796

Following gene: 119897794

Centisome position: 37.62

GC content: 74.8

Gene sequence:

>1476_bases
ATGCGGCGGCGGGAAGATGGCGGCCCCGTGCTGCCTTTCCGCCCCGCGCTTTCGATGAATCCGCTGCGCTCCGCCGCCTC
CGCGACGCATCCCTTCCGCCCCACCGCCAGCGCCGCCGCCTTCGACCTGCAACGCGCGCTGCTGCTGCGGCTGTTGGTGT
TCGGCCTCGCCGCCTCGCTGCTGGCGCTTGCCGCCCACGGCTGGCGCGGCCACCACCAGGCGCTCGCGGACCTCGCGCCC
ACCGGCGCCATCGTGCAGCAATTGCTCAACCAGGATCAGCCGCGGCTGGCCGATCCCTTCAACCGCGAGCAGATCGCCAC
CGACCTCGGCGTGCTCGCACCGCTCGCGCGCCGGCTGGCCTTCTGCGTCGAGGTCGAAGACCTGTGGGGCCGGGTGATCG
CGCAGGACTGCGTCGCGCCCACGCCGCCGCTGGCCGGCACCGCTACGCCCGCCGGCTGGCTGGCGGCGCTCGCGGGGGAC
GCCGGCAGCGCCCGCTATGCGCTGCTGCGCCCGCCCGGCGTCAGCGTCGGCGAGATCCGGGTGTCGCCCTACTGGGCGGC
CGAACTCTCCGGCTGGCTCGGCGTGCTCGGCCTGCTAGCGCTGGCGTGGGCGGCACTGGCGGCGCTCGCGGCCGCGCTGA
TCGCCCCGGTGCGGCGTGCGCTGCGCCCGGCCGACCGCATCCTCGCCGCCATCGGCCAGCTCGAAGCCGGCGACACCGCG
GTGCGCCTGCCCGAGTTCGAATTGCGCGAATTCCGCCGCATCGGCGAGGACTTCAACAGCCTCGCCTCCCAGCTCGGCGA
GACCCGCGCCGCCGAACGCCGGCTCGCCACCGGCCTGCTCGACGCGCGCGAGGCCGAGCGCCGCCACCTCGCCCGCGAAC
TGCACGACGACATGGGCCAGCACCTCACCTCGCTGCGCGCCGAAACCGCCTTCCTGCGCCACGGAGCCGGTGAAAACGCC
GCGCTGCAGCCTAGCCTGGACTCGATCGAAGCCAGCCTCGCCCAGCTGCACGAGAGCGTGCAGGACATCGTCCACCGCCT
GCGCCCGCCGGGACTGGACGCTTTCGGCCTGGGCGAATGCCTGCGTCAGTTGGTCCGCGAGGTACGACGCCGCCCCGATG
GCACCGCAGTTGCCACCACGCTGACGCTGGACGGCGATATCGACGCCCTGCCCGGCGAATGCGCGGCGCACGCCTACCGC
ATCGTCCAGGAAGGCCTCACCAACGCGCTGCGCCACGCGCGCGCCAGCCGGGTGGCGGTAACGCTCGCCTGCGCCGCCGG
CAGCGTGACGGTGGAGGTGACCGACGATGGCGTCGCCGATGCGATCAACGGCGGCGGGCGCGGCGGCCACGGCCTTGCCG
GCATCGCGGAACGGGTCGCGGCCCTGGGCGGCAGCGTGGAACTCGCGCCGCTGGCCACCGGCGGCATGCGGCTCGCCGCC
GCATGGCCACTGCCCGCGACGGAGGTGGCGGCATGA

Upstream 100 bases:

>100_bases
GCAACGTGCAGCTAATGCTGGAGCACTTCGAAGCGGCCTGAGCGCCCGGCCGGCGTCACGGGCAAATTGCCCGCCGCGCC
GCCGCCCGCTTCCATTCGGA

Downstream 100 bases:

>100_bases
TCCGCCTGCTGCTGGTGGACGACCACGCAGTGGTGCGCCAGGGCTATCGCCGCCTGCTCGAACAGCAGGGCAACCTCGTG
GTCGCCGGCGAGGCCGCCAC

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MRRREDGGPVLPFRPALSMNPLRSAASATHPFRPTASAAAFDLQRALLLRLLVFGLAASLLALAAHGWRGHHQALADLAP
TGAIVQQLLNQDQPRLADPFNREQIATDLGVLAPLARRLAFCVEVEDLWGRVIAQDCVAPTPPLAGTATPAGWLAALAGD
AGSARYALLRPPGVSVGEIRVSPYWAAELSGWLGVLGLLALAWAALAALAAALIAPVRRALRPADRILAAIGQLEAGDTA
VRLPEFELREFRRIGEDFNSLASQLGETRAAERRLATGLLDAREAERRHLARELHDDMGQHLTSLRAETAFLRHGAGENA
ALQPSLDSIEASLAQLHESVQDIVHRLRPPGLDAFGLGECLRQLVREVRRRPDGTAVATTLTLDGDIDALPGECAAHAYR
IVQEGLTNALRHARASRVAVTLACAAGSVTVEVTDDGVADAINGGGRGGHGLAGIAERVAALGGSVELAPLATGGMRLAA
AWPLPATEVAA

Sequences:

>Translated_491_residues
MRRREDGGPVLPFRPALSMNPLRSAASATHPFRPTASAAAFDLQRALLLRLLVFGLAASLLALAAHGWRGHHQALADLAP
TGAIVQQLLNQDQPRLADPFNREQIATDLGVLAPLARRLAFCVEVEDLWGRVIAQDCVAPTPPLAGTATPAGWLAALAGD
AGSARYALLRPPGVSVGEIRVSPYWAAELSGWLGVLGLLALAWAALAALAAALIAPVRRALRPADRILAAIGQLEAGDTA
VRLPEFELREFRRIGEDFNSLASQLGETRAAERRLATGLLDAREAERRHLARELHDDMGQHLTSLRAETAFLRHGAGENA
ALQPSLDSIEASLAQLHESVQDIVHRLRPPGLDAFGLGECLRQLVREVRRRPDGTAVATTLTLDGDIDALPGECAAHAYR
IVQEGLTNALRHARASRVAVTLACAAGSVTVEVTDDGVADAINGGGRGGHGLAGIAERVAALGGSVELAPLATGGMRLAA
AWPLPATEVAA
>Mature_491_residues
MRRREDGGPVLPFRPALSMNPLRSAASATHPFRPTASAAAFDLQRALLLRLLVFGLAASLLALAAHGWRGHHQALADLAP
TGAIVQQLLNQDQPRLADPFNREQIATDLGVLAPLARRLAFCVEVEDLWGRVIAQDCVAPTPPLAGTATPAGWLAALAGD
AGSARYALLRPPGVSVGEIRVSPYWAAELSGWLGVLGLLALAWAALAALAAALIAPVRRALRPADRILAAIGQLEAGDTA
VRLPEFELREFRRIGEDFNSLASQLGETRAAERRLATGLLDAREAERRHLARELHDDMGQHLTSLRAETAFLRHGAGENA
ALQPSLDSIEASLAQLHESVQDIVHRLRPPGLDAFGLGECLRQLVREVRRRPDGTAVATTLTLDGDIDALPGECAAHAYR
IVQEGLTNALRHARASRVAVTLACAAGSVTVEVTDDGVADAINGGGRGGHGLAGIAERVAALGGSVELAPLATGGMRLAA
AWPLPATEVAA

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression. May function as a membrane-associated protein kinase that phosphorylates moxX in response to environmental signals [H]

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=233, Percent_Identity=33.4763948497854, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788812, Length=232, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787474, Length=229, Percent_Identity=26.2008733624454, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712 [H]

Pfam domain/function: PF00672 HAMP; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 51659; Mature: 51659

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRREDGGPVLPFRPALSMNPLRSAASATHPFRPTASAAAFDLQRALLLRLLVFGLAASL
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LALAAHGWRGHHQALADLAPTGAIVQQLLNQDQPRLADPFNREQIATDLGVLAPLARRLA
HHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FCVEVEDLWGRVIAQDCVAPTPPLAGTATPAGWLAALAGDAGSARYALLRPPGVSVGEIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEE
VSPYWAAELSGWLGVLGLLALAWAALAALAAALIAPVRRALRPADRILAAIGQLEAGDTA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCE
VRLPEFELREFRRIGEDFNSLASQLGETRAAERRLATGLLDAREAERRHLARELHDDMGQ
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLTSLRAETAFLRHGAGENAALQPSLDSIEASLAQLHESVQDIVHRLRPPGLDAFGLGEC
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LRQLVREVRRRPDGTAVATTLTLDGDIDALPGECAAHAYRIVQEGLTNALRHARASRVAV
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TLACAAGSVTVEVTDDGVADAINGGGRGGHGLAGIAERVAALGGSVELAPLATGGMRLAA
EEEEECCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
AWPLPATEVAA
ECCCCHHHHCC
>Mature Secondary Structure
MRRREDGGPVLPFRPALSMNPLRSAASATHPFRPTASAAAFDLQRALLLRLLVFGLAASL
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LALAAHGWRGHHQALADLAPTGAIVQQLLNQDQPRLADPFNREQIATDLGVLAPLARRLA
HHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FCVEVEDLWGRVIAQDCVAPTPPLAGTATPAGWLAALAGDAGSARYALLRPPGVSVGEIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEE
VSPYWAAELSGWLGVLGLLALAWAALAALAAALIAPVRRALRPADRILAAIGQLEAGDTA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCE
VRLPEFELREFRRIGEDFNSLASQLGETRAAERRLATGLLDAREAERRHLARELHDDMGQ
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLTSLRAETAFLRHGAGENAALQPSLDSIEASLAQLHESVQDIVHRLRPPGLDAFGLGEC
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LRQLVREVRRRPDGTAVATTLTLDGDIDALPGECAAHAYRIVQEGLTNALRHARASRVAV
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TLACAAGSVTVEVTDDGVADAINGGGRGGHGLAGIAERVAALGGSVELAPLATGGMRLAA
EEEEECCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
AWPLPATEVAA
ECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]