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The map label for this gene is cheA2 [H]

Identifier: 119897742

GI number: 119897742

Start: 1580242

End: 1582332

Strand: Direct

Name: cheA2 [H]

Synonym: azo1451

Alternate gene names: 119897742

Gene position: 1580242-1582332 (Clockwise)

Preceding gene: 119897741

Following gene: 119897743

Centisome position: 36.11

GC content: 71.74

Gene sequence:

>2091_bases
ATGGCGTTCGACATGAGCCAGTTCTACCAGATCTTCTTCGAAGAGGCGGCGGAACACCTGGCGACAATCGAGACCGTGCT
GCTGTCGATCGACGCGGCGCGCCCCGACCCCGAGAAGGTCGCGGAGATCTTCCGCGCCGCGCACTCCATCAAGGGGTCGG
CCGCCACCTTCGGCTTCGACGATCTCACCGGCCTCACCCACGAGATGGAGTCCTTGCTCGACGACGTGCGGCGCGGCCGG
CGGCCGTTGACCCAGGCGATGGTCCAGGCCTGTCTTGCCGCGGGCGACGCGCTGCACGGCCTGCTCGCGGCGCACCGCGG
CGAGGGCGTTGCGGACCGCGCCGCCGCCGAGGCCGCCCGTCAGCGCCTGCTGCAGCTCAAGGACGCGCCCGATCACGATG
CCGCGGTGACGGACCCCCCGGCGGCGGCTGTGCCCGACGCGACGGAGTGGCCGCTCTACCGTGTGCGCTTCGTCGTCGCG
CGCTTTCTTGCCGGCAGCGATCTGCTGTTCGGCAGCATGCTGGAAGACCTCGCGGCGCTCGGCGACTACGAACTGCTGGA
GCCGGATCCCGCCGCACCCGGCACGCGCTGCATCAGGATCTGCAGCGGCGAGTCGGTGGATGCGTTGCGCGCGGCCTTCG
AGCGCCTCGCCGAGCCCGGCAGCGTCGAGATCACCGCCGAGCAGATGGCTGCCGCAAACGCGGCCCCGGCGCTGCCCGAG
CCCCAGCCTCCGGCGGTGGCGGCGGCGGGCGACGAGGCGCTGTTCGATGTCGCCGACGACGGCAGCTACGGCTTCTTCGT
GCCGCTCGAGACCCTACCCGCGGCGCCGTTTGGCACCGACGATCCGCCCGCCGCGGCCGTGCCGGACGAGGCCGATGCCC
AGCCGGCCGCGACCGCGCGCGAGCTGCCCCGCAGCGCGGACAGTTCGATCCGCGTCGGGGTCGAGCGGGTGGACCGGATG
ATGGACCTCGTGGGCGAACTGGTGATCACCCAGTCGATGCTGCTCGATGCGGCGGCGGCGATCGGCCCCGCCGCCGGAGA
GCGCCTGCTCGCCGGGCTTGCGCTGCTGCAGCGGCACACGCGCGATCTGCAGCAGTCGGTGATGGCGATCCGCATGGTGC
CGGTGTCGATGGTGTTCTCCCGTTTTCCGCGCCTGGTGCACGACCTCGGCATGCGGCTCGACAAGCAGATCGACCTGGTA
CTGGAAGGCGAGCACACCGAACTCGACAAGGGGCTGGTGGAAAAGCTGGCCGACCCGCTCACGCATCTGGTGCGCAACTG
CATCGACCATGGCATCGAGCCCGCCGAGCGCCGACGCGCGGCCGGCAAGCCCGAGGCCGGCCGGCTGCGGCTGGCGGCGT
CGCACCTTGGCGGCCATGTGCTGATCGAGGTGGAGGACGACGGCGCGGGGCTGGACCGGGAGCGGCTGATCGCCCGCGCG
CGCGCGCAGGGCCTGCCGTGCAGCGAGGACATGAGTGACGAGGAGGCCTGGCAACTGATCTTCCTGCCCGGCTTTTCCAC
CGCCGAGCAGGTCACCGACCTGTCCGGGCGCGGCGTCGGCATGGATGTCGTCCGGCGCAACATCGCGGCGCTGGGCGGGC
GGGTGGACATCGTCTCGCGCGCGGGGCGGGGCACGCGGTTCTCGGTCAGCGTGCCGCTGACGCTCGCCATCCTGGAAGGC
ATGCAGGTGGCCGTGGGCGACGAGGTCTTCATCCTGCCGCTCGATGCGATCGTCGAATCGCTGCAGCCCGAGCGGGCCAG
CGTCCGCAGCATTGGCGGCGCGCCGCGGCTGATTGCGGTGCGCGGCGAATACTGGCCGGTGGTCGAACTCGGCCACTTCT
TCGCCGTGCCCGAGGCGGGCCGCGACTGGACGCGCGGCATCATGGTGCTGGTGGAGCGCAACGGCAGCCGCGCGGCGCTG
TTCGTGGATGGTCTGGTCGGACAGCAGCAGGTGGTGATCAAGCCGCTCGAAACCCACTTCCGGCGCGTCCCGGGCGTGTC
TTCCGCAACCTTGCTCGGCGACGGCCGCGTCGCGCTGATCCTCGACGTCGCCGCCCTGATCGGCACCGCGCGCGACAGCG
CGGCGATCTGA

Upstream 100 bases:

>100_bases
CGGGCGCGAGGCCGGCGCCACCGGCTGGCTGGTGAAACCCTTCGATCCCGACCGCCTGCTGGAAGTGGTGCGCCGGGTGC
TGGGCTAGGAGGCAGCAGCG

Downstream 100 bases:

>100_bases
TGGCGCGGCGCTACAGATTGACCGCCGGCGGCCGTAGACCGATCAAAGCAATCAAGGAGTCCGAACATGTCAGCCCCTGA
CCGACCGGCGCTGGCGCCGG

Product: chemotaxis protein cheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MAFDMSQFYQIFFEEAAEHLATIETVLLSIDAARPDPEKVAEIFRAAHSIKGSAATFGFDDLTGLTHEMESLLDDVRRGR
RPLTQAMVQACLAAGDALHGLLAAHRGEGVADRAAAEAARQRLLQLKDAPDHDAAVTDPPAAAVPDATEWPLYRVRFVVA
RFLAGSDLLFGSMLEDLAALGDYELLEPDPAAPGTRCIRICSGESVDALRAAFERLAEPGSVEITAEQMAAANAAPALPE
PQPPAVAAAGDEALFDVADDGSYGFFVPLETLPAAPFGTDDPPAAAVPDEADAQPAATARELPRSADSSIRVGVERVDRM
MDLVGELVITQSMLLDAAAAIGPAAGERLLAGLALLQRHTRDLQQSVMAIRMVPVSMVFSRFPRLVHDLGMRLDKQIDLV
LEGEHTELDKGLVEKLADPLTHLVRNCIDHGIEPAERRRAAGKPEAGRLRLAASHLGGHVLIEVEDDGAGLDRERLIARA
RAQGLPCSEDMSDEEAWQLIFLPGFSTAEQVTDLSGRGVGMDVVRRNIAALGGRVDIVSRAGRGTRFSVSVPLTLAILEG
MQVAVGDEVFILPLDAIVESLQPERASVRSIGGAPRLIAVRGEYWPVVELGHFFAVPEAGRDWTRGIMVLVERNGSRAAL
FVDGLVGQQQVVIKPLETHFRRVPGVSSATLLGDGRVALILDVAALIGTARDSAAI

Sequences:

>Translated_696_residues
MAFDMSQFYQIFFEEAAEHLATIETVLLSIDAARPDPEKVAEIFRAAHSIKGSAATFGFDDLTGLTHEMESLLDDVRRGR
RPLTQAMVQACLAAGDALHGLLAAHRGEGVADRAAAEAARQRLLQLKDAPDHDAAVTDPPAAAVPDATEWPLYRVRFVVA
RFLAGSDLLFGSMLEDLAALGDYELLEPDPAAPGTRCIRICSGESVDALRAAFERLAEPGSVEITAEQMAAANAAPALPE
PQPPAVAAAGDEALFDVADDGSYGFFVPLETLPAAPFGTDDPPAAAVPDEADAQPAATARELPRSADSSIRVGVERVDRM
MDLVGELVITQSMLLDAAAAIGPAAGERLLAGLALLQRHTRDLQQSVMAIRMVPVSMVFSRFPRLVHDLGMRLDKQIDLV
LEGEHTELDKGLVEKLADPLTHLVRNCIDHGIEPAERRRAAGKPEAGRLRLAASHLGGHVLIEVEDDGAGLDRERLIARA
RAQGLPCSEDMSDEEAWQLIFLPGFSTAEQVTDLSGRGVGMDVVRRNIAALGGRVDIVSRAGRGTRFSVSVPLTLAILEG
MQVAVGDEVFILPLDAIVESLQPERASVRSIGGAPRLIAVRGEYWPVVELGHFFAVPEAGRDWTRGIMVLVERNGSRAAL
FVDGLVGQQQVVIKPLETHFRRVPGVSSATLLGDGRVALILDVAALIGTARDSAAI
>Mature_695_residues
AFDMSQFYQIFFEEAAEHLATIETVLLSIDAARPDPEKVAEIFRAAHSIKGSAATFGFDDLTGLTHEMESLLDDVRRGRR
PLTQAMVQACLAAGDALHGLLAAHRGEGVADRAAAEAARQRLLQLKDAPDHDAAVTDPPAAAVPDATEWPLYRVRFVVAR
FLAGSDLLFGSMLEDLAALGDYELLEPDPAAPGTRCIRICSGESVDALRAAFERLAEPGSVEITAEQMAAANAAPALPEP
QPPAVAAAGDEALFDVADDGSYGFFVPLETLPAAPFGTDDPPAAAVPDEADAQPAATARELPRSADSSIRVGVERVDRMM
DLVGELVITQSMLLDAAAAIGPAAGERLLAGLALLQRHTRDLQQSVMAIRMVPVSMVFSRFPRLVHDLGMRLDKQIDLVL
EGEHTELDKGLVEKLADPLTHLVRNCIDHGIEPAERRRAAGKPEAGRLRLAASHLGGHVLIEVEDDGAGLDRERLIARAR
AQGLPCSEDMSDEEAWQLIFLPGFSTAEQVTDLSGRGVGMDVVRRNIAALGGRVDIVSRAGRGTRFSVSVPLTLAILEGM
QVAVGDEVFILPLDAIVESLQPERASVRSIGGAPRLIAVRGEYWPVVELGHFFAVPEAGRDWTRGIMVLVERNGSRAALF
VDGLVGQQQVVIKPLETHFRRVPGVSSATLLGDGRVALILDVAALIGTARDSAAI

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=427, Percent_Identity=54.3325526932084, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74302; Mature: 74170

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDMSQFYQIFFEEAAEHLATIETVLLSIDAARPDPEKVAEIFRAAHSIKGSAATFGFD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCH
DLTGLTHEMESLLDDVRRGRRPLTQAMVQACLAAGDALHGLLAAHRGEGVADRAAAEAAR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QRLLQLKDAPDHDAAVTDPPAAAVPDATEWPLYRVRFVVARFLAGSDLLFGSMLEDLAAL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GDYELLEPDPAAPGTRCIRICSGESVDALRAAFERLAEPGSVEITAEQMAAANAAPALPE
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCC
PQPPAVAAAGDEALFDVADDGSYGFFVPLETLPAAPFGTDDPPAAAVPDEADAQPAATAR
CCCCCEEECCCCCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ELPRSADSSIRVGVERVDRMMDLVGELVITQSMLLDAAAAIGPAAGERLLAGLALLQRHT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
RDLQQSVMAIRMVPVSMVFSRFPRLVHDLGMRLDKQIDLVLEGEHTELDKGLVEKLADPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
THLVRNCIDHGIEPAERRRAAGKPEAGRLRLAASHLGGHVLIEVEDDGAGLDRERLIARA
HHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEHHCCCEEEEEECCCCCCCCHHHHHHHH
RAQGLPCSEDMSDEEAWQLIFLPGFSTAEQVTDLSGRGVGMDVVRRNIAALGGRVDIVSR
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEHHC
AGRGTRFSVSVPLTLAILEGMQVAVGDEVFILPLDAIVESLQPERASVRSIGGAPRLIAV
CCCCCEEEEECCHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHHCCCCCEEEEE
RGEYWPVVELGHFFAVPEAGRDWTRGIMVLVERNGSRAALFVDGLVGQQQVVIKPLETHF
CCCCCCCEECCCEEECCCCCCCHHCEEEEEEECCCCEEEEEEECCCCCCHHEEEHHHHHH
RRVPGVSSATLLGDGRVALILDVAALIGTARDSAAI
HHCCCCCCEEEECCCCEEHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AFDMSQFYQIFFEEAAEHLATIETVLLSIDAARPDPEKVAEIFRAAHSIKGSAATFGFD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCH
DLTGLTHEMESLLDDVRRGRRPLTQAMVQACLAAGDALHGLLAAHRGEGVADRAAAEAAR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QRLLQLKDAPDHDAAVTDPPAAAVPDATEWPLYRVRFVVARFLAGSDLLFGSMLEDLAAL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GDYELLEPDPAAPGTRCIRICSGESVDALRAAFERLAEPGSVEITAEQMAAANAAPALPE
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCC
PQPPAVAAAGDEALFDVADDGSYGFFVPLETLPAAPFGTDDPPAAAVPDEADAQPAATAR
CCCCCEEECCCCCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ELPRSADSSIRVGVERVDRMMDLVGELVITQSMLLDAAAAIGPAAGERLLAGLALLQRHT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
RDLQQSVMAIRMVPVSMVFSRFPRLVHDLGMRLDKQIDLVLEGEHTELDKGLVEKLADPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
THLVRNCIDHGIEPAERRRAAGKPEAGRLRLAASHLGGHVLIEVEDDGAGLDRERLIARA
HHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEHHCCCEEEEEECCCCCCCCHHHHHHHH
RAQGLPCSEDMSDEEAWQLIFLPGFSTAEQVTDLSGRGVGMDVVRRNIAALGGRVDIVSR
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEHHC
AGRGTRFSVSVPLTLAILEGMQVAVGDEVFILPLDAIVESLQPERASVRSIGGAPRLIAV
CCCCCEEEEECCHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHHCCCCCEEEEE
RGEYWPVVELGHFFAVPEAGRDWTRGIMVLVERNGSRAALFVDGLVGQQQVVIKPLETHF
CCCCCCCEECCCEEECCCCCCCHHCEEEEEEECCCCEEEEEEECCCCCCHHEEEHHHHHH
RRVPGVSSATLLGDGRVALILDVAALIGTARDSAAI
HHCCCCCCEEEECCCCEEHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]