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The map label for this gene is hoxH [H]

Identifier: 119897706

GI number: 119897706

Start: 1546567

End: 1548030

Strand: Direct

Name: hoxH [H]

Synonym: azo1415

Alternate gene names: 119897706

Gene position: 1546567-1548030 (Clockwise)

Preceding gene: 119897705

Following gene: 119897707

Centisome position: 35.34

GC content: 69.81

Gene sequence:

>1464_bases
ATGAGCGAACACCTTCAACCGACAGTGCAGCAGGACGGCCTGCGCCGGGTCGCGATCGACCCGGTGTCGCGCGTGGAAGG
CCATGGCAAGGTCACGCTGCTGCTCGATGCAGACGGCGAGGTGTGCGAGGCGCGCCTGCACATCGTCGAGTTCCGTGGCT
TCGAGGTCTTCGTGCAGGGGCGGCCGTACTGGGAAGTGCCGGTCATCGTGCAGCGCCTGTGCGGCATCTGCCCGGTCAGT
CATCACCTTGCCGCGTGCAAGGCGCTCGACCACGTGGTGGGTGCCGCCCCGGTGCCGGCCAGCGCCGACCGCCTGCGCCG
GCTGATGCACTACGGGCAGATCCTGCAGTCGCATGCGCTCCACTTCTTCCATCTGGCTTCGCCCGACCTGCTGTTCGGCT
TCGACGCCGAACCCGCGCGGCGCAACATCCTCGCGGTCGCCGCTGCGTACCCGGAGATCGCGCGGCAAGGCGTAATGCTG
CGCAAGTTTGGGCAGGAGGTCATCCGCGCCACGGCCGGCAAGCGCATCCACGGCACCGGCGCGGTGCCCGGCGGCATGAA
CCGCCATCTCGCGCCGGCCGACCATGCGCTGCTGTTGGCGGGCATCGACGAGGTGCTGACGTGGTGCCGCGGCGCAGTGG
AACTGGTGCGCCGGCTGCACGACGCCGACGCCGCGTTCTACGACAGCTTCGGCACCGTGGCGTCGGGCTTCATGAGCCTG
GTCGGGGAGGGCGGCGGGCTCGAGTTCTACGACGGCACGCTGCGCTTCCGTGATGCCGACGGGCAGATCGTCCGCGACGG
CGTGGCCGATCGCGACTATCACCGCGTGCTGCGCGAGGCGGTGAAGCCCTGGAGCTACATGAAGTTTCCCTACCTCGCGG
AGCGCGGGCCGGAGCAGGGCTGGTACAAGGTCGGGCCGCTGGCGCGGGTGCAGAACTGCGATTTCATTCCCACCCCGCTG
GCCGAGTCCGAACGTCGCGCGTTCCTCGATTACGGTGGCGGGCGCCCGCTGCATGCGCCGCTCGCCTACCACTGGGCACG
CATGATCGAAATGCTGCACGCCGCCGAGCTGATCCGCGACCTGCTGGAGGACCCCGCGCTGTTGGCGGGGCCGCTGACCG
CCGCGGGGCCGCGGGCAAGCGAGGGCGTCGGCGTCATCGAGGCACCGCGCGGTACGCTGATCCACCACTACCGCGTGGGC
GAGGACGACCTGGTGACGATGTGCAACCTGATCGTGTCGACGACCCACAACAACGAGGCGATGAACGCCGCGGTGCGGGC
GGTGGCGCGCCAGACGGTGTCGAAGCAGACCTTGACCGAGGCGGCGCTGAACAGCATCGAGGTGGCAATCCGCGCCTTCG
ACCCCTGTCTGTCCTGCGCGACCCACGCGCTGGGCAGGATGCCGCTGGAGCTCGCGCTGGTGGGGGCCGACGGCGCACTG
ATCGAGCGGGTGCTGCGGGATTGA

Upstream 100 bases:

>100_bases
CCGCCCTCGGGCGATGCGATCTGGAAATTCCTGTCCGACCTCGTGGCCGGCCGCACCCCGCGGCTGCCCTACGCATTGAT
GCATTTCGACTGAGCCGGCG

Downstream 100 bases:

>100_bases
TGCCGCCGGCAAAGGCGCGGCAACGGGAGAAATGAGCATGCAGCTTGTCGTGATCGCGGTGGGCAACGATGCGCGTGGCG
ACGACGCGCTCGGCCCGCTG

Product: hydrogen dehydrogenase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSEHLQPTVQQDGLRRVAIDPVSRVEGHGKVTLLLDADGEVCEARLHIVEFRGFEVFVQGRPYWEVPVIVQRLCGICPVS
HHLAACKALDHVVGAAPVPASADRLRRLMHYGQILQSHALHFFHLASPDLLFGFDAEPARRNILAVAAAYPEIARQGVML
RKFGQEVIRATAGKRIHGTGAVPGGMNRHLAPADHALLLAGIDEVLTWCRGAVELVRRLHDADAAFYDSFGTVASGFMSL
VGEGGGLEFYDGTLRFRDADGQIVRDGVADRDYHRVLREAVKPWSYMKFPYLAERGPEQGWYKVGPLARVQNCDFIPTPL
AESERRAFLDYGGGRPLHAPLAYHWARMIEMLHAAELIRDLLEDPALLAGPLTAAGPRASEGVGVIEAPRGTLIHHYRVG
EDDLVTMCNLIVSTTHNNEAMNAAVRAVARQTVSKQTLTEAALNSIEVAIRAFDPCLSCATHALGRMPLELALVGADGAL
IERVLRD

Sequences:

>Translated_487_residues
MSEHLQPTVQQDGLRRVAIDPVSRVEGHGKVTLLLDADGEVCEARLHIVEFRGFEVFVQGRPYWEVPVIVQRLCGICPVS
HHLAACKALDHVVGAAPVPASADRLRRLMHYGQILQSHALHFFHLASPDLLFGFDAEPARRNILAVAAAYPEIARQGVML
RKFGQEVIRATAGKRIHGTGAVPGGMNRHLAPADHALLLAGIDEVLTWCRGAVELVRRLHDADAAFYDSFGTVASGFMSL
VGEGGGLEFYDGTLRFRDADGQIVRDGVADRDYHRVLREAVKPWSYMKFPYLAERGPEQGWYKVGPLARVQNCDFIPTPL
AESERRAFLDYGGGRPLHAPLAYHWARMIEMLHAAELIRDLLEDPALLAGPLTAAGPRASEGVGVIEAPRGTLIHHYRVG
EDDLVTMCNLIVSTTHNNEAMNAAVRAVARQTVSKQTLTEAALNSIEVAIRAFDPCLSCATHALGRMPLELALVGADGAL
IERVLRD
>Mature_486_residues
SEHLQPTVQQDGLRRVAIDPVSRVEGHGKVTLLLDADGEVCEARLHIVEFRGFEVFVQGRPYWEVPVIVQRLCGICPVSH
HLAACKALDHVVGAAPVPASADRLRRLMHYGQILQSHALHFFHLASPDLLFGFDAEPARRNILAVAAAYPEIARQGVMLR
KFGQEVIRATAGKRIHGTGAVPGGMNRHLAPADHALLLAGIDEVLTWCRGAVELVRRLHDADAAFYDSFGTVASGFMSLV
GEGGGLEFYDGTLRFRDADGQIVRDGVADRDYHRVLREAVKPWSYMKFPYLAERGPEQGWYKVGPLARVQNCDFIPTPLA
ESERRAFLDYGGGRPLHAPLAYHWARMIEMLHAAELIRDLLEDPALLAGPLTAAGPRASEGVGVIEAPRGTLIHHYRVGE
DDLVTMCNLIVSTTHNNEAMNAAVRAVARQTVSKQTLTEAALNSIEVAIRAFDPCLSCATHALGRMPLELALVGADGALI
ERVLRD

Specific function: This Is One Of Three E.Coli Hydrogenases Synthesized In Response To Different Physiological Conditions. Hyd1 Is Believed To Have A Role In Hydrogen Cycling During Fermentative Growth. [C]

COG id: COG3259

COG function: function code C; Coenzyme F420-reducing hydrogenase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family [H]

Homologues:

Organism=Escherichia coli, GI1787207, Length=149, Percent_Identity=30.2013422818792, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789368, Length=129, Percent_Identity=29.4573643410853, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001501
- InterPro:   IPR018194 [H]

Pfam domain/function: PF00374 NiFeSe_Hases [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 53292; Mature: 53161

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00507 NI_HGENASE_L_1 ; PS00508 NI_HGENASE_L_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHLQPTVQQDGLRRVAIDPVSRVEGHGKVTLLLDADGEVCEARLHIVEFRGFEVFVQG
CCCCCCCHHHHCCCEEEECCCHHHCCCCCCEEEEECCCCHHHHHHHEEEEECCEEEEECC
RPYWEVPVIVQRLCGICPVSHHLAACKALDHVVGAAPVPASADRLRRLMHYGQILQSHAL
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCH
HFFHLASPDLLFGFDAEPARRNILAVAAAYPEIARQGVMLRKFGQEVIRATAGKRIHGTG
HEEEECCCCEEEECCCCHHHHHEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCC
AVPGGMNRHLAPADHALLLAGIDEVLTWCRGAVELVRRLHDADAAFYDSFGTVASGFMSL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEGGGLEFYDGTLRFRDADGQIVRDGVADRDYHRVLREAVKPWSYMKFPYLAERGPEQG
HCCCCCEEEECCEEEEECCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
WYKVGPLARVQNCDFIPTPLAESERRAFLDYGGGRPLHAPLAYHWARMIEMLHAAELIRD
CEECCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLEDPALLAGPLTAAGPRASEGVGVIEAPRGTLIHHYRVGEDDLVTMCNLIVSTTHNNEA
HHHCCCEEECCCCCCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCHH
MNAAVRAVARQTVSKQTLTEAALNSIEVAIRAFDPCLSCATHALGRMPLELALVGADGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHH
IERVLRD
HHHHHCC
>Mature Secondary Structure 
SEHLQPTVQQDGLRRVAIDPVSRVEGHGKVTLLLDADGEVCEARLHIVEFRGFEVFVQG
CCCCCCHHHHCCCEEEECCCHHHCCCCCCEEEEECCCCHHHHHHHEEEEECCEEEEECC
RPYWEVPVIVQRLCGICPVSHHLAACKALDHVVGAAPVPASADRLRRLMHYGQILQSHAL
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCH
HFFHLASPDLLFGFDAEPARRNILAVAAAYPEIARQGVMLRKFGQEVIRATAGKRIHGTG
HEEEECCCCEEEECCCCHHHHHEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCC
AVPGGMNRHLAPADHALLLAGIDEVLTWCRGAVELVRRLHDADAAFYDSFGTVASGFMSL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEGGGLEFYDGTLRFRDADGQIVRDGVADRDYHRVLREAVKPWSYMKFPYLAERGPEQG
HCCCCCEEEECCEEEEECCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
WYKVGPLARVQNCDFIPTPLAESERRAFLDYGGGRPLHAPLAYHWARMIEMLHAAELIRD
CEECCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLEDPALLAGPLTAAGPRASEGVGVIEAPRGTLIHHYRVGEDDLVTMCNLIVSTTHNNEA
HHHCCCEEECCCCCCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCHH
MNAAVRAVARQTVSKQTLTEAALNSIEVAIRAFDPCLSCATHALGRMPLELALVGADGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHH
IERVLRD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]