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The map label for this gene is nuoC

Identifier: 119897689

GI number: 119897689

Start: 1525851

End: 1526456

Strand: Direct

Name: nuoC

Synonym: azo1398

Alternate gene names: 119897689

Gene position: 1525851-1526456 (Clockwise)

Preceding gene: 119897688

Following gene: 119897690

Centisome position: 34.87

GC content: 57.59

Gene sequence:

>606_bases
ATGAGTGCCAAGCTTGAACGCCTGAGTCAAACGCTTCGCGATGTCCTCGGTGATGTTGTTGAGTCGCTGGTGGTGGATCG
CGGCGAGGTGACGATAGAAGTCGCCGCCGGAAATTTTCTTGATGTTGCCCGCAGGCTGCGAGACGAGGCTGCGCTCGGTT
TCGAGCAGCTGATGGATATCTCCGGTATCGACTATTCCGCCTTTGGCAATGGTGCCTGGCAAGGCAAGCGATTTGCCTCT
GTTGCGCACCTGCTGTCCGTCAAGAATAACTGGCGCCTGCGGCTTCGCGTGTTTGCGGATGACGATGACTTTCCGGTCCT
GGGTTCGCTCGTCGAAGTGTGGCCTAGCGCGAACTGGTTTGAACGCGAGGCGTTCGATCTTTACGGAATTCTCTACGCAG
GCCATCCGGATCTTCGTCGTATCCTGACCGACTACGGTTTCGTCGGTCATCCGTTCCGCAAGGATTTCCCCATCTCGGGC
TACGTAGAAATGCGCTATGACCCGGAGCAGGGGCGCGTGGTGTATCAGCCGGTAACGATCGAGCCTCGCGAGAATACCCC
GCGCATCGTGCGTGAAGAGAATTACGGGGATGTCGGTCATGGCTGA

Upstream 100 bases:

>100_bases
GTCCGCCGACGGCCGAGGCATTGTTGTACGGCATTATTCAGCTGCAGAACAAGATCAAGCGGACCAACACGATTGCCCGC
TGATTGACGGATGCCCAGAC

Downstream 100 bases:

>100_bases
AATTCGCAACTACACGATCAACTTCGGTCCGCAGCATCCGTCGGCGCACGGTGTGCTGCGCCTGGTTCTGGAACTGGATG
GCGAAGTCGTCGAGCGCGCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSAKLERLSQTLRDVLGDVVESLVVDRGEVTIEVAAGNFLDVARRLRDEAALGFEQLMDISGIDYSAFGNGAWQGKRFAS
VAHLLSVKNNWRLRLRVFADDDDFPVLGSLVEVWPSANWFEREAFDLYGILYAGHPDLRRILTDYGFVGHPFRKDFPISG
YVEMRYDPEQGRVVYQPVTIEPRENTPRIVREENYGDVGHG

Sequences:

>Translated_201_residues
MSAKLERLSQTLRDVLGDVVESLVVDRGEVTIEVAAGNFLDVARRLRDEAALGFEQLMDISGIDYSAFGNGAWQGKRFAS
VAHLLSVKNNWRLRLRVFADDDDFPVLGSLVEVWPSANWFEREAFDLYGILYAGHPDLRRILTDYGFVGHPFRKDFPISG
YVEMRYDPEQGRVVYQPVTIEPRENTPRIVREENYGDVGHG
>Mature_200_residues
SAKLERLSQTLRDVLGDVVESLVVDRGEVTIEVAAGNFLDVARRLRDEAALGFEQLMDISGIDYSAFGNGAWQGKRFASV
AHLLSVKNNWRLRLRVFADDDDFPVLGSLVEVWPSANWFEREAFDLYGILYAGHPDLRRILTDYGFVGHPFRKDFPISGY
VEMRYDPEQGRVVYQPVTIEPRENTPRIVREENYGDVGHG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=178, Percent_Identity=40.4494382022472, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI145693162, Length=80, Percent_Identity=42.5, Blast_Score=77, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=173, Percent_Identity=41.0404624277457, Blast_Score=126, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71990788, Length=173, Percent_Identity=41.0404624277457, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24656494, Length=176, Percent_Identity=42.6136363636364, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_AZOSB (A1K5B0)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932902.1
- ProteinModelPortal:   A1K5B0
- SMR:   A1K5B0
- STRING:   A1K5B0
- GeneID:   4609420
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo1398
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- BioCyc:   ASP62928:AZO1398-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 22852; Mature: 22721

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKLERLSQTLRDVLGDVVESLVVDRGEVTIEVAAGNFLDVARRLRDEAALGFEQLMDI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCHHHHHHC
SGIDYSAFGNGAWQGKRFASVAHLLSVKNNWRLRLRVFADDDDFPVLGSLVEVWPSANWF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCC
EREAFDLYGILYAGHPDLRRILTDYGFVGHPFRKDFPISGYVEMRYDPEQGRVVYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECEEE
EPRENTPRIVREENYGDVGHG
CCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
SAKLERLSQTLRDVLGDVVESLVVDRGEVTIEVAAGNFLDVARRLRDEAALGFEQLMDI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCHHHHHHC
SGIDYSAFGNGAWQGKRFASVAHLLSVKNNWRLRLRVFADDDDFPVLGSLVEVWPSANWF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCC
EREAFDLYGILYAGHPDLRRILTDYGFVGHPFRKDFPISGYVEMRYDPEQGRVVYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECEEE
EPRENTPRIVREENYGDVGHG
CCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA