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The map label for this gene is ywlC [H]

Identifier: 119897671

GI number: 119897671

Start: 1507398

End: 1508429

Strand: Direct

Name: ywlC [H]

Synonym: azo1380

Alternate gene names: 119897671

Gene position: 1507398-1508429 (Clockwise)

Preceding gene: 119897670

Following gene: 119897672

Centisome position: 34.45

GC content: 70.25

Gene sequence:

>1032_bases
ATGAGGCCGCTCGGCGTCGTGCCGGCGCAGGAAGACAACATCCAGAGTGCTGCGGAGGCGCTGCGCGCAGGCGAACTTGT
CGGCCTGCCGACCGAAACCGTGTATGGGCTGGCGGCTGACGCGCGCAATCCCGTCGCGGTGCGCAGGATTTTTGCGGCGA
AGGGACGGCCAGCAGATCATCCACTGATCGTGCACCTGCCCGCGCTCGATCAGCTGTCGCAGTGGGCGGCCGCCGTTCCG
GTTGAAGCCGTTGCGCTCGGCCGCGCCTTCTGGCCTGGCCCGCTGACGCTCATCCTCAGGCGCCAGCCGCACGTTCCCGA
CGAAGTCACTGGCGGTCAGGATACGGTGGGCGTGCGGGTGCCCGCCCATCCGGCCGCGCTGGCGTTGCTTGCAGCCTTCG
GGTCCGGGCTCGCGGCACCCAGTGCCAATCGCTTCGGGCGCATCAGCCCCACGACCGCGGCTCATGTGGCCGAAGAGTTG
GGTGATGCGGTTGCGATGGTGATCGACGGCGGCGCGTGCGAGGTCGGCATCGAATCCACCATTCTCGATCTTTCCCGACT
CGACACCTGCGGGCCGGTGATCCTGCGACCGGGTGCGATTTCCGCCGACGCGATTGCAGCGGTGATCGGCCAGCGTCCGC
TGGGACGCGCCGAAAGCGAGGGGGCGGGCGGAGCGCAGGCGCCGCGGGTGGCGGGTGCGCTTGCCGCACACTACGCACCG
CGTACGCCGATGCGCCTGGTCGAGCCCGCTGCACTTGCCGACGAGGCGGGCCGGCAACTGGCCGCCGGTGTCCGCACCGG
TGTGCTTGTGCGCGCGGGGGCATCGTTTCCGCGCGGCGTCACCGTGCGGATGGCGCCCGCCGACGTCGAAGGTTACGCGC
ACGCGCTCTACGCAAACCTGCGTGATCTCGACGCGGCGGAGCTGGATCTCATCCTGGTTGAGGCAGTGCCGCTGGAGACG
GCATGGGACGCGGTGCACGACAGGCTGGGCCGTGCGGCGGTGGGGGCGGGTCTGGAACAGGACGAGACCTGA

Upstream 100 bases:

>100_bases
CGGGGCGCAAGATGGGGCATTTCACGGTGGTGGGCGAGGATCAGGCGGCCGTGCTGGCGCAGGCCTTGCGTGCTCGCGGC
GCGATCGGGGTGACTGACGA

Downstream 100 bases:

>100_bases
GAAAAAATGCGCGGCGGGCACTTCCCAATCGTCGGACTCTTGCCTATAATGCTCGCTCTTTCGGGCCGATAGCTCAGCTG
GGAGAGCGCTGCGTTCGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRPLGVVPAQEDNIQSAAEALRAGELVGLPTETVYGLAADARNPVAVRRIFAAKGRPADHPLIVHLPALDQLSQWAAAVP
VEAVALGRAFWPGPLTLILRRQPHVPDEVTGGQDTVGVRVPAHPAALALLAAFGSGLAAPSANRFGRISPTTAAHVAEEL
GDAVAMVIDGGACEVGIESTILDLSRLDTCGPVILRPGAISADAIAAVIGQRPLGRAESEGAGGAQAPRVAGALAAHYAP
RTPMRLVEPAALADEAGRQLAAGVRTGVLVRAGASFPRGVTVRMAPADVEGYAHALYANLRDLDAAELDLILVEAVPLET
AWDAVHDRLGRAAVGAGLEQDET

Sequences:

>Translated_343_residues
MRPLGVVPAQEDNIQSAAEALRAGELVGLPTETVYGLAADARNPVAVRRIFAAKGRPADHPLIVHLPALDQLSQWAAAVP
VEAVALGRAFWPGPLTLILRRQPHVPDEVTGGQDTVGVRVPAHPAALALLAAFGSGLAAPSANRFGRISPTTAAHVAEEL
GDAVAMVIDGGACEVGIESTILDLSRLDTCGPVILRPGAISADAIAAVIGQRPLGRAESEGAGGAQAPRVAGALAAHYAP
RTPMRLVEPAALADEAGRQLAAGVRTGVLVRAGASFPRGVTVRMAPADVEGYAHALYANLRDLDAAELDLILVEAVPLET
AWDAVHDRLGRAAVGAGLEQDET
>Mature_343_residues
MRPLGVVPAQEDNIQSAAEALRAGELVGLPTETVYGLAADARNPVAVRRIFAAKGRPADHPLIVHLPALDQLSQWAAAVP
VEAVALGRAFWPGPLTLILRRQPHVPDEVTGGQDTVGVRVPAHPAALALLAAFGSGLAAPSANRFGRISPTTAAHVAEEL
GDAVAMVIDGGACEVGIESTILDLSRLDTCGPVILRPGAISADAIAAVIGQRPLGRAESEGAGGAQAPRVAGALAAHYAP
RTPMRLVEPAALADEAGRQLAAGVRTGVLVRAGASFPRGVTVRMAPADVEGYAHALYANLRDLDAAELDLILVEAVPLET
AWDAVHDRLGRAAVGAGLEQDET

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=212, Percent_Identity=31.1320754716981, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI2367210, Length=160, Percent_Identity=32.5, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081864, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=234, Percent_Identity=29.0598290598291, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=385, Percent_Identity=30.6493506493506, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI78707274, Length=179, Percent_Identity=30.7262569832402, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35231; Mature: 35231

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLGVVPAQEDNIQSAAEALRAGELVGLPTETVYGLAADARNPVAVRRIFAAKGRPADH
CCCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
PLIVHLPALDQLSQWAAAVPVEAVALGRAFWPGPLTLILRRQPHVPDEVTGGQDTVGVRV
CEEEEECCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEC
PAHPAALALLAAFGSGLAAPSANRFGRISPTTAAHVAEELGDAVAMVIDGGACEVGIEST
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCEECHHHH
ILDLSRLDTCGPVILRPGAISADAIAAVIGQRPLGRAESEGAGGAQAPRVAGALAAHYAP
HHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
RTPMRLVEPAALADEAGRQLAAGVRTGVLVRAGASFPRGVTVRMAPADVEGYAHALYANL
CCCHHHHCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
RDLDAAELDLILVEAVPLETAWDAVHDRLGRAAVGAGLEQDET
HHCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRPLGVVPAQEDNIQSAAEALRAGELVGLPTETVYGLAADARNPVAVRRIFAAKGRPADH
CCCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
PLIVHLPALDQLSQWAAAVPVEAVALGRAFWPGPLTLILRRQPHVPDEVTGGQDTVGVRV
CEEEEECCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEC
PAHPAALALLAAFGSGLAAPSANRFGRISPTTAAHVAEELGDAVAMVIDGGACEVGIEST
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCEECHHHH
ILDLSRLDTCGPVILRPGAISADAIAAVIGQRPLGRAESEGAGGAQAPRVAGALAAHYAP
HHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
RTPMRLVEPAALADEAGRQLAAGVRTGVLVRAGASFPRGVTVRMAPADVEGYAHALYANL
CCCHHHHCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
RDLDAAELDLILVEAVPLETAWDAVHDRLGRAAVGAGLEQDET
HHCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]