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The map label for this gene is FtsK [H]

Identifier: 119897656

GI number: 119897656

Start: 1485243

End: 1487531

Strand: Direct

Name: FtsK [H]

Synonym: azo1365

Alternate gene names: 119897656

Gene position: 1485243-1487531 (Clockwise)

Preceding gene: 119897655

Following gene: 119897657

Centisome position: 33.94

GC content: 66.1

Gene sequence:

>2289_bases
ATGTTGCCTCGTTCGTCCCGTTCCCAGCCCCTGCCGGAAAAGATTTCGCTGCTGTTGCAGGAGGCGCGCTGGCTCATTCT
CGGCGTGATGTCGCTGTACGTCGGCCTGGTGCTCATCGGCTACAACAAGGCCGACCCCGGTTGGTCGCACGCCGCCGAGG
TGGCGCGCGTGGCCAATCCCGGCGGACGATTCGGTGCCTGGCTGGCCGACCTGCTGCTATACCTGTTCGGTATCTCGGCG
TGGTGGTGGGTGGTGTTCCTCGGCTATAGCCTGATGTGGGGCTTTCGCCGGCTGAAGAACCAGCTGACGCTCGACCGCCG
TTCGTTTTTCTTCGTGCTCGTCGGCTTTTTCAGCGTGCTCGTCACCAGCAGCGCGCTCGAGTACCTCCGCTTCCATTCGC
ACGGCGTCGCGGTGCCGCTCAGCCCGGGCGGGCTGCTCGGCATGGAGTTCGGACAACTCGTGCAGCGCTATCTTGGCTAC
ACCGGCGGCACACTGATGTTGCTCGCGCTGATGGCGTCCGGGCTGTCGCTGTTTACCGGTGTGTCCTGGCTCGCCGCGGT
GGAGCGGGTAGGGCTGGCGATCGAGCAGGCGGTGGCTGGCGCCCAGCAGGCTTACTACCGCTGGCTGGACCGGAAGGCCG
GGCGCCAGGTGGCCGAAAAGCGCGAGGCGGTGGTGGAGACGCGGCGCAAGAAGACCGAACAGGCGCCCGCCGCGCCGCTG
CGCATCGAACCCGCCGTCACCGTGGTGCAGAAATCCGAGCGGGTGGAGAAGGAGCGCCAGCAGACGCTCTTTGCCGACGC
GGTCGAAGGTGCGATTCCCCCGCTCAGCCTGCTCGACCCTGCCTCGGGCGATATCGAGCCGCCGTCGGCCGAGTCGCTCG
AATTCACCTCGCGGCTGATCGAAACCAAGCTTGGCGACTTCGGCGTCGAGGTCAAGGTGCTGGCCGCCTATCCGGGCCCG
GTGATTACCCGCTACGAAATCGAACCGGCCACCGGCGTGAAGGGCAGCCAGGTGGTCAACCTCGCCAAGGATCTGGCCCG
CGCGCTGTCGCTGGTGTCGGTGCGGGTGGTCGAAACGGTGCCGGGCAAATCGTGCATGGCGCTGGAACTGCCCAATCCCA
AGCGCCAGACGGTGCGCCTGTCGGAAATCGTCGGCTCCAAGGCTTATCACGACATGGCGTCGCCGCTCACGGTCGTGCTC
GGCAAGGACATCGGCGGCCAGCCGGTGGTGGCCGACCTCGCCAAGATGCCGCATCTGCTGGTGGCCGGTACCACCGGCTC
CGGCAAATCGGTGGGCATCAACGCCATGATCCTGTCCCTGCTCTACAAGAGCGAACCCGAGCGGGTGCGGATGATCATGG
TCGACCCGAAGATGCTGGAACTGTCGATCTACGAAGGCATTCCGCACCTGCTGGCCCCGGTGGTCACCGACATGAAGCAC
GCGGCCAACGCGCTCAACTGGTGCGTCGCAGAAATGGAAAAGCGCTACAAGCTGATGGCGGCCGTCGGCGTGCGTAACCT
GGCGGGGTTCAACAAGGCCGTGCTGGAGGCGCGGAAGGCTGAGGCACCGCTGACCAATCCGTTTGCGATCAACCCGGACA
ATCCGGAGCCGCTGGAGACGCTGCCCTATATCGTGGTGGTGGTGGATGAACTCGCCGACATGATGATGGTGGTCGGCAAG
AAGGTCGAAGAGCTCATCGCCCGTCTGGCGCAGAAGGCGCGCGCGGCCGGCATCCATCTCATCCTCGCCACCCAGCGGCC
GTCGGTGGATGTCATCACCGGCCTGATCAAGGCCAACGTGCCCACCCGCATCGCCTTCCAGGTGTCGAGCAAGATCGACT
CGCGCACCATCCTCGACCAGATGGGGGCGGAGACCCTGCTCGGCATGGGCGACATGCTCTATCTCGCGCCGGGTACCGGC
CTGCCGGTGCGGGTGCATGGTGCCTTCGTGGCCGACGAGGAAGTGCACAAGGTGGTCGACCACCTCAAGCGCGTCGGCCC
GCCGGACTACATCGACGGCATCCTTGCCGCGCCCGAGGACGACCTCGAGGCGCTCGCCGGGGCGGGCGGTGAGGATGGCG
ACGGCGAGGCCGATCCGCTCTACGACCAGGCAGTCGAGGTGGTGCTGAAAACGCGGCGGCCGTCGATCTCGCTGGTGCAA
CGCCACCTGCGCATCGGTTACAACCGCTCGGCACGGCTCATCGAACAGATGGAGCGCGCGGGGCTGGTGTCGCCCATGGG
CAGTAACGGCAATCGTGAAGTCATCGTGCCGGCGAAGGAGGCCGAATGA

Upstream 100 bases:

>100_bases
GATTGTGAGCAAGGGCAAACCGCGGCCGGGCAGGTGGGGTGATCGCATATAATCCCACCTGTTGTTTTTTGCAGTTGTCC
GCCTCAGGTTGCCCCCGCCG

Downstream 100 bases:

>100_bases
AGCGCGTCCTGGGGATGAATGCCGGTCATTGGGGGGCGCTGGTCGTATGCGCCGCCCTGGTCTTCGGCACGCGCTGCGCG
GTCGCCGCGGACGGCGTGGA

Product: putative cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MLPRSSRSQPLPEKISLLLQEARWLILGVMSLYVGLVLIGYNKADPGWSHAAEVARVANPGGRFGAWLADLLLYLFGISA
WWWVVFLGYSLMWGFRRLKNQLTLDRRSFFFVLVGFFSVLVTSSALEYLRFHSHGVAVPLSPGGLLGMEFGQLVQRYLGY
TGGTLMLLALMASGLSLFTGVSWLAAVERVGLAIEQAVAGAQQAYYRWLDRKAGRQVAEKREAVVETRRKKTEQAPAAPL
RIEPAVTVVQKSERVEKERQQTLFADAVEGAIPPLSLLDPASGDIEPPSAESLEFTSRLIETKLGDFGVEVKVLAAYPGP
VITRYEIEPATGVKGSQVVNLAKDLARALSLVSVRVVETVPGKSCMALELPNPKRQTVRLSEIVGSKAYHDMASPLTVVL
GKDIGGQPVVADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKSEPERVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKH
AANALNWCVAEMEKRYKLMAAVGVRNLAGFNKAVLEARKAEAPLTNPFAINPDNPEPLETLPYIVVVVDELADMMMVVGK
KVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAETLLGMGDMLYLAPGTG
LPVRVHGAFVADEEVHKVVDHLKRVGPPDYIDGILAAPEDDLEALAGAGGEDGDGEADPLYDQAVEVVLKTRRPSISLVQ
RHLRIGYNRSARLIEQMERAGLVSPMGSNGNREVIVPAKEAE

Sequences:

>Translated_762_residues
MLPRSSRSQPLPEKISLLLQEARWLILGVMSLYVGLVLIGYNKADPGWSHAAEVARVANPGGRFGAWLADLLLYLFGISA
WWWVVFLGYSLMWGFRRLKNQLTLDRRSFFFVLVGFFSVLVTSSALEYLRFHSHGVAVPLSPGGLLGMEFGQLVQRYLGY
TGGTLMLLALMASGLSLFTGVSWLAAVERVGLAIEQAVAGAQQAYYRWLDRKAGRQVAEKREAVVETRRKKTEQAPAAPL
RIEPAVTVVQKSERVEKERQQTLFADAVEGAIPPLSLLDPASGDIEPPSAESLEFTSRLIETKLGDFGVEVKVLAAYPGP
VITRYEIEPATGVKGSQVVNLAKDLARALSLVSVRVVETVPGKSCMALELPNPKRQTVRLSEIVGSKAYHDMASPLTVVL
GKDIGGQPVVADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKSEPERVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKH
AANALNWCVAEMEKRYKLMAAVGVRNLAGFNKAVLEARKAEAPLTNPFAINPDNPEPLETLPYIVVVVDELADMMMVVGK
KVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAETLLGMGDMLYLAPGTG
LPVRVHGAFVADEEVHKVVDHLKRVGPPDYIDGILAAPEDDLEALAGAGGEDGDGEADPLYDQAVEVVLKTRRPSISLVQ
RHLRIGYNRSARLIEQMERAGLVSPMGSNGNREVIVPAKEAE
>Mature_762_residues
MLPRSSRSQPLPEKISLLLQEARWLILGVMSLYVGLVLIGYNKADPGWSHAAEVARVANPGGRFGAWLADLLLYLFGISA
WWWVVFLGYSLMWGFRRLKNQLTLDRRSFFFVLVGFFSVLVTSSALEYLRFHSHGVAVPLSPGGLLGMEFGQLVQRYLGY
TGGTLMLLALMASGLSLFTGVSWLAAVERVGLAIEQAVAGAQQAYYRWLDRKAGRQVAEKREAVVETRRKKTEQAPAAPL
RIEPAVTVVQKSERVEKERQQTLFADAVEGAIPPLSLLDPASGDIEPPSAESLEFTSRLIETKLGDFGVEVKVLAAYPGP
VITRYEIEPATGVKGSQVVNLAKDLARALSLVSVRVVETVPGKSCMALELPNPKRQTVRLSEIVGSKAYHDMASPLTVVL
GKDIGGQPVVADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKSEPERVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKH
AANALNWCVAEMEKRYKLMAAVGVRNLAGFNKAVLEARKAEAPLTNPFAINPDNPEPLETLPYIVVVVDELADMMMVVGK
KVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAETLLGMGDMLYLAPGTG
LPVRVHGAFVADEEVHKVVDHLKRVGPPDYIDGILAAPEDDLEALAGAGGEDGDGEADPLYDQAVEVVLKTRRPSISLVQ
RHLRIGYNRSARLIEQMERAGLVSPMGSNGNREVIVPAKEAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=491, Percent_Identity=64.969450101833, Blast_Score=629, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 82822; Mature: 82822

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure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HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]