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The map label for this gene is ttdR [H]

Identifier: 119897538

GI number: 119897538

Start: 1343604

End: 1344530

Strand: Direct

Name: ttdR [H]

Synonym: azo1247

Alternate gene names: 119897538

Gene position: 1343604-1344530 (Clockwise)

Preceding gene: 119897536

Following gene: 119897539

Centisome position: 30.7

GC content: 70.77

Gene sequence:

>927_bases
ATGGACGCCGTCGCTTCCGAACTCGCCTTCTTCCTGCTGCTGGCCGACAAGGGTTCCTTCACCGCCGCCGCGCGCGAACT
CAACCTCACGCCGCCGGCGGTCAGCAAGCGGCTGGCGCAGATCGAGCAGCGCCTGGGTGTGCGCCTGCTCAACCGCAGCA
CGCGGCGGGTCAGCCTCACCGACGAGGGCGAGCTGTACCTGGAGCATGCGCGCCGCATCGTGGCCGACATCGAGGACATG
GAAGCCTCGCTCGGCAGCCGGCGGGCGGCGCCGAAGGGGCTGCTGCGGGTCAATGCCACGCTCGGTTTCGGCCGCACCAC
CATCGCGCCCATCGTGTCGGCCTTCGCGCGCCAGCATCCGGAGGTGGAAGTGCAGCTGCAGCTCACCGACGCGCCGATCG
ATCTGGTCGCGACCGGCTTCGATCTCGCGATCCGCTTCGGCGAGTTGCCGGACAGCCGGCTGTCGGCGCGCAAGCTGATG
AGCAACCGCCGCTTCCTGTGCGCCTCGCCGGCCTATCTCGACGCCCACGGCACGCCGCAGACGCCGGCCGAACTCGCCCG
CCACGCCTGCATCCTCCACCGCCAGAACGACGACGCCTACGGCATCTGGCGCCTGGCGCGCGGGCGGCACGTGGAGACGG
TGAAGGTGCGCGGCACGCTGTCGTCCAACGATGGCGACGTGGTGCTGGGCTGGGCGCTCGACGGCCACGGCATCCTGATC
CGCTCCGAGTGGGATCTGGCCAAGTACCTGGAGAGCGGGCGGCTGCGCGCGGTGCTGCCGGACTACACGTTGCCCACCGC
AGACCTCTACGCGGTGTATCCGGCGCGGCGCAACCAGCCCGCGCGGGTGCGCGCCTTCATCGACTTCCTGCTTGCCCGCT
TTGCACCGGCGGGCGGTGCGCCGGGTGCGCAATTGTCGAGCGTCTGA

Upstream 100 bases:

>100_bases
GGAGGAGTTCAGTCGCCGTAACGAAACGCCCCCAGCTTATTGAATTCCAGAAGCCGTAGAATCTATAAAAACTCAATTCA
TTAAGTCGTAGAAGTTAAAA

Downstream 100 bases:

>100_bases
CACAGGCCGCGGCGCCATCCGGCCCCGTTACAGTCGAACAATCCGCATCGAATCATGGGTTTGGCTCGGGTGCGCTCCGC
GGGCGGCACTGGCACTCATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDAVASELAFFLLLADKGSFTAAARELNLTPPAVSKRLAQIEQRLGVRLLNRSTRRVSLTDEGELYLEHARRIVADIEDM
EASLGSRRAAPKGLLRVNATLGFGRTTIAPIVSAFARQHPEVEVQLQLTDAPIDLVATGFDLAIRFGELPDSRLSARKLM
SNRRFLCASPAYLDAHGTPQTPAELARHACILHRQNDDAYGIWRLARGRHVETVKVRGTLSSNDGDVVLGWALDGHGILI
RSEWDLAKYLESGRLRAVLPDYTLPTADLYAVYPARRNQPARVRAFIDFLLARFAPAGGAPGAQLSSV

Sequences:

>Translated_308_residues
MDAVASELAFFLLLADKGSFTAAARELNLTPPAVSKRLAQIEQRLGVRLLNRSTRRVSLTDEGELYLEHARRIVADIEDM
EASLGSRRAAPKGLLRVNATLGFGRTTIAPIVSAFARQHPEVEVQLQLTDAPIDLVATGFDLAIRFGELPDSRLSARKLM
SNRRFLCASPAYLDAHGTPQTPAELARHACILHRQNDDAYGIWRLARGRHVETVKVRGTLSSNDGDVVLGWALDGHGILI
RSEWDLAKYLESGRLRAVLPDYTLPTADLYAVYPARRNQPARVRAFIDFLLARFAPAGGAPGAQLSSV
>Mature_308_residues
MDAVASELAFFLLLADKGSFTAAARELNLTPPAVSKRLAQIEQRLGVRLLNRSTRRVSLTDEGELYLEHARRIVADIEDM
EASLGSRRAAPKGLLRVNATLGFGRTTIAPIVSAFARQHPEVEVQLQLTDAPIDLVATGFDLAIRFGELPDSRLSARKLM
SNRRFLCASPAYLDAHGTPQTPAELARHACILHRQNDDAYGIWRLARGRHVETVKVRGTLSSNDGDVVLGWALDGHGILI
RSEWDLAKYLESGRLRAVLPDYTLPTADLYAVYPARRNQPARVRAFIDFLLARFAPAGGAPGAQLSSV

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=40.4682274247492, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=42.0689655172414, Blast_Score=230, Evalue=7e-62,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=35.7615894039735, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=32.3024054982818, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=31.0104529616725, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=29.1095890410959, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=31.1418685121107, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=27.7027027027027, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789173, Length=277, Percent_Identity=28.158844765343, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786448, Length=276, Percent_Identity=25.7246376811594, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=156, Percent_Identity=31.4102564102564, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=167, Percent_Identity=26.9461077844311, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788297, Length=223, Percent_Identity=25.5605381165919, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=173, Percent_Identity=26.0115606936416, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081904, Length=149, Percent_Identity=30.8724832214765, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=132, Percent_Identity=31.0606060606061, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33783; Mature: 33783

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVASELAFFLLLADKGSFTAAARELNLTPPAVSKRLAQIEQRLGVRLLNRSTRRVSLT
CCHHHHHHEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
DEGELYLEHARRIVADIEDMEASLGSRRAAPKGLLRVNATLGFGRTTIAPIVSAFARQHP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCC
EVEVQLQLTDAPIDLVATGFDLAIRFGELPDSRLSARKLMSNRRFLCASPAYLDAHGTPQ
CEEEEEEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCEEECCCCCC
TPAELARHACILHRQNDDAYGIWRLARGRHVETVKVRGTLSSNDGDVVLGWALDGHGILI
CHHHHHHHHEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEECCCEEEE
RSEWDLAKYLESGRLRAVLPDYTLPTADLYAVYPARRNQPARVRAFIDFLLARFAPAGGA
ECCCHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PGAQLSSV
CCCCCCCC
>Mature Secondary Structure
MDAVASELAFFLLLADKGSFTAAARELNLTPPAVSKRLAQIEQRLGVRLLNRSTRRVSLT
CCHHHHHHEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
DEGELYLEHARRIVADIEDMEASLGSRRAAPKGLLRVNATLGFGRTTIAPIVSAFARQHP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCC
EVEVQLQLTDAPIDLVATGFDLAIRFGELPDSRLSARKLMSNRRFLCASPAYLDAHGTPQ
CEEEEEEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCEEECCCCCC
TPAELARHACILHRQNDDAYGIWRLARGRHVETVKVRGTLSSNDGDVVLGWALDGHGILI
CHHHHHHHHEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEECCCEEEE
RSEWDLAKYLESGRLRAVLPDYTLPTADLYAVYPARRNQPARVRAFIDFLLARFAPAGGA
ECCCHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
PGAQLSSV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]