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The map label for this gene is flhA [H]

Identifier: 119897395

GI number: 119897395

Start: 1187481

End: 1189580

Strand: Direct

Name: flhA [H]

Synonym: azo1104

Alternate gene names: 119897395

Gene position: 1187481-1189580 (Clockwise)

Preceding gene: 119897394

Following gene: 119897396

Centisome position: 27.14

GC content: 67.1

Gene sequence:

>2100_bases
ATGAACGCCCTGAACCTGCGCGAACTCTTCTCCGTCAGCAACCTGCGCCAGCTGTCGGCTCCGATCCTCATCGTCATGAT
CCTGTCGATGATGGTGTTGCCGCTGCCGGTGTTCCTGCTCGACGTCTTCTTCACCTTCAACATTGCGGTATCGGTGATGG
TGATGCTGGTGGCGATGTACTCGAAGAAGCCGCTGGACTTCTCGGTATTCCCCACCGTGCTGCTGGTGACCACGCTGCTG
CGGCTGTCGCTGAACGTCGCCTCCACCCGGATCGTGCTGCTCAACGGCCACAGCGGGCCGGATGCGGCCGGCAAGGTCAT
CGAGGCCTTCGGCCACTTCCTGGTGGGCGGCAACACTGCGGTCGGCATCGTGGTGTTTGTCATCCTCACCATCATCAACT
TCGTCGTCATCACCAAGGGCGCCGGGCGGATCGCCGAAGTGAGCGCGCGCTTCACGCTGGATGCGATGCCCGGCAAGCAG
ATGGCGATCGACGCCGACCTCAATGCCGGCCTGATCGACGAGAAGACCGCCAAGGCGCGGCGCAAGGAGATCGCGCAGGA
AGCCGACTTCTACGGCGCGATGGACGGTGCGTCCAAGTTCGTGCGCGGCGATGCGGTGGCCGGCATCCTGATCCTGGTCA
TCAACATCATCGGCGGGCTGTTCGTCGGTGTGGTCCAGCACAACATGGCGGCCGGTGATGCCGCCCACACCTACACGCTG
CTGACCATCGGTGACGGCCTCGTGGCGCAGATCCCGGCGCTGATCATCTCGGTGGCGGCGGGCCTGGTGGTGTCGCGCGT
GGGTGACGAGGGCGACATCGGCGGGTTGGTCATCGGCCAGCTCTTCAGCAACCCGCAGGTGCTCGCGCTCACCGCCGGCA
TCATCGGCGTGCTGGGCCTCATTCCCGGCATGCCGAACTTCGTGTTCCTGCTGCTCGCCGCCGGGTTGGGATGGCTGGCG
TGGTCACGCAACCGCAAACTGATGGAGCCCGAGAGCGTCGCCCAGACGCAGGCGGCAGCTGCCCAGGCCGCCGCGGCCGC
GCCGCAGGCCGAAGCGCAGGAGGCGAGCTGGAACGACGTCGCGCCGGTCGATGTGCTCGGGCTGGAAGTGGGTTACCGGC
TGATCCCGATGGTGGACAAGGGCCAGGATGGCGAGCTGCTCAAGCGTATCCGCGGCCTGCGCAAGAAGTTCGCGCAGGAG
GTCGGCTTCCTGTCGGCGCCGGTCCATATCCGCGACAACCTGGAACTCAAGCCCAATGCCTACCGGATCGCGCTGAAAGG
CGTGGAAATCGGCAGCGGCGAGGCCTATCCCGGCCAGTACCTGGCAATCAACCCCGGCCGCGTGTCCGGCCCGATGAGCG
GACGCGAAACCAAGGATCCGGCCTTCGGGCTGCCGGCCTACTGGATCGACGCCGGCAGTCGCGAGCAGGCCCACGGGCTG
GGCTATACGGTGGTCGATGCCAGCACCGTGGTCGCCACCCATCTCAACCACCTCATCCTCAACCACGCGGCGGAACTGCT
CGGCCGCCAGGAAACCCAGGCGCTGCTCGACCACATCGGCAAGGAATCGCCCAAGCTGGTCGACGACCTGGTGCCCAAGC
TGCTGCCGATCTCCGCGGTGCAGCGGGTGCTGCAGAATCTGCTGGACGAAGGCGTCAACATCCGCGACATGCGCACCATC
ATCGAGGTGCTCGCCGAGTTCGCGCCGCGCAACCAGGACCCGGTGGAGCTCACCAGCAAGGTCCGCGAGGCGCTCGGCCG
CGCGATCATCCAGGGGCTGTTCCCGGGTACCGCCGAGGTTCAGGTGATGGCGCTGGAGCCCAGCCTGGAACGCATCCTGA
TGCAGGCAATGAGCGCGAGCGGCGAGGGCGGTGCGATCGAACCCGGGCTGGCCGACACCCTGCTGCGCCAGACCGCGCAG
ATCGCCCAGCGCCAGGAAGACATCGGCCTGCCGCCGGTGCTGCTGGTGCCGGCGCCGCTGCGCATGCTGCTGTCGCGCTT
CCTGCGTCGCGCGGTGCCCACGCTCAAGGTCATCTCCAACGCCGAGGTGCCGGAGTCGCGCACGATCCGCGTCACCGCCA
TGGTCGGCGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
TGGAAAGCGGCGGCCTGCCGCCCACGACGCCGTCCGAACTGCCGGTGCCCGAGGGCATGGACCCCGGCTCGCCGGACGAG
GCCTGAGTGCCGCCTGAACC

Downstream 100 bases:

>100_bases
CCCCCGCCCCCGGCGCCGCTCGACGCATGCGGCGAGTGGAATAAGCGGGGGAAAGCCGGTTTATTCGCCCCATGGCGGGT
AGGGCCGGCTGGCGATAATC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MNALNLRELFSVSNLRQLSAPILIVMILSMMVLPLPVFLLDVFFTFNIAVSVMVMLVAMYSKKPLDFSVFPTVLLVTTLL
RLSLNVASTRIVLLNGHSGPDAAGKVIEAFGHFLVGGNTAVGIVVFVILTIINFVVITKGAGRIAEVSARFTLDAMPGKQ
MAIDADLNAGLIDEKTAKARRKEIAQEADFYGAMDGASKFVRGDAVAGILILVINIIGGLFVGVVQHNMAAGDAAHTYTL
LTIGDGLVAQIPALIISVAAGLVVSRVGDEGDIGGLVIGQLFSNPQVLALTAGIIGVLGLIPGMPNFVFLLLAAGLGWLA
WSRNRKLMEPESVAQTQAAAAQAAAAAPQAEAQEASWNDVAPVDVLGLEVGYRLIPMVDKGQDGELLKRIRGLRKKFAQE
VGFLSAPVHIRDNLELKPNAYRIALKGVEIGSGEAYPGQYLAINPGRVSGPMSGRETKDPAFGLPAYWIDAGSREQAHGL
GYTVVDASTVVATHLNHLILNHAAELLGRQETQALLDHIGKESPKLVDDLVPKLLPISAVQRVLQNLLDEGVNIRDMRTI
IEVLAEFAPRNQDPVELTSKVREALGRAIIQGLFPGTAEVQVMALEPSLERILMQAMSASGEGGAIEPGLADTLLRQTAQ
IAQRQEDIGLPPVLLVPAPLRMLLSRFLRRAVPTLKVISNAEVPESRTIRVTAMVGAAA

Sequences:

>Translated_699_residues
MNALNLRELFSVSNLRQLSAPILIVMILSMMVLPLPVFLLDVFFTFNIAVSVMVMLVAMYSKKPLDFSVFPTVLLVTTLL
RLSLNVASTRIVLLNGHSGPDAAGKVIEAFGHFLVGGNTAVGIVVFVILTIINFVVITKGAGRIAEVSARFTLDAMPGKQ
MAIDADLNAGLIDEKTAKARRKEIAQEADFYGAMDGASKFVRGDAVAGILILVINIIGGLFVGVVQHNMAAGDAAHTYTL
LTIGDGLVAQIPALIISVAAGLVVSRVGDEGDIGGLVIGQLFSNPQVLALTAGIIGVLGLIPGMPNFVFLLLAAGLGWLA
WSRNRKLMEPESVAQTQAAAAQAAAAAPQAEAQEASWNDVAPVDVLGLEVGYRLIPMVDKGQDGELLKRIRGLRKKFAQE
VGFLSAPVHIRDNLELKPNAYRIALKGVEIGSGEAYPGQYLAINPGRVSGPMSGRETKDPAFGLPAYWIDAGSREQAHGL
GYTVVDASTVVATHLNHLILNHAAELLGRQETQALLDHIGKESPKLVDDLVPKLLPISAVQRVLQNLLDEGVNIRDMRTI
IEVLAEFAPRNQDPVELTSKVREALGRAIIQGLFPGTAEVQVMALEPSLERILMQAMSASGEGGAIEPGLADTLLRQTAQ
IAQRQEDIGLPPVLLVPAPLRMLLSRFLRRAVPTLKVISNAEVPESRTIRVTAMVGAAA
>Mature_699_residues
MNALNLRELFSVSNLRQLSAPILIVMILSMMVLPLPVFLLDVFFTFNIAVSVMVMLVAMYSKKPLDFSVFPTVLLVTTLL
RLSLNVASTRIVLLNGHSGPDAAGKVIEAFGHFLVGGNTAVGIVVFVILTIINFVVITKGAGRIAEVSARFTLDAMPGKQ
MAIDADLNAGLIDEKTAKARRKEIAQEADFYGAMDGASKFVRGDAVAGILILVINIIGGLFVGVVQHNMAAGDAAHTYTL
LTIGDGLVAQIPALIISVAAGLVVSRVGDEGDIGGLVIGQLFSNPQVLALTAGIIGVLGLIPGMPNFVFLLLAAGLGWLA
WSRNRKLMEPESVAQTQAAAAQAAAAAPQAEAQEASWNDVAPVDVLGLEVGYRLIPMVDKGQDGELLKRIRGLRKKFAQE
VGFLSAPVHIRDNLELKPNAYRIALKGVEIGSGEAYPGQYLAINPGRVSGPMSGRETKDPAFGLPAYWIDAGSREQAHGL
GYTVVDASTVVATHLNHLILNHAAELLGRQETQALLDHIGKESPKLVDDLVPKLLPISAVQRVLQNLLDEGVNIRDMRTI
IEVLAEFAPRNQDPVELTSKVREALGRAIIQGLFPGTAEVQVMALEPSLERILMQAMSASGEGGAIEPGLADTLLRQTAQ
IAQRQEDIGLPPVLLVPAPLRMLLSRFLRRAVPTLKVISNAEVPESRTIRVTAMVGAAA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=680, Percent_Identity=64.7058823529412, Blast_Score=843, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74434; Mature: 74434

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNLRELFSVSNLRQLSAPILIVMILSMMVLPLPVFLLDVFFTFNIAVSVMVMLVAMY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKPLDFSVFPTVLLVTTLLRLSLNVASTRIVLLNGHSGPDAAGKVIEAFGHFLVGGNTA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHEECCCHH
VGIVVFVILTIINFVVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIDEKTAKAR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
RKEIAQEADFYGAMDGASKFVRGDAVAGILILVINIIGGLFVGVVQHNMAAGDAAHTYTL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEE
LTIGDGLVAQIPALIISVAAGLVVSRVGDEGDIGGLVIGQLFSNPQVLALTAGIIGVLGL
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHH
IPGMPNFVFLLLAAGLGWLAWSRNRKLMEPESVAQTQAAAAQAAAAAPQAEAQEASWNDV
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
APVDVLGLEVGYRLIPMVDKGQDGELLKRIRGLRKKFAQEVGFLSAPVHIRDNLELKPNA
CCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCE
YRIALKGVEIGSGEAYPGQYLAINPGRVSGPMSGRETKDPAFGLPAYWIDAGSREQAHGL
EEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
GYTVVDASTVVATHLNHLILNHAAELLGRQETQALLDHIGKESPKLVDDLVPKLLPISAV
CEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
QRVLQNLLDEGVNIRDMRTIIEVLAEFAPRNQDPVELTSKVREALGRAIIQGLFPGTAEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
QVMALEPSLERILMQAMSASGEGGAIEPGLADTLLRQTAQIAQRQEDIGLPPVLLVPAPL
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHH
RMLLSRFLRRAVPTLKVISNAEVPESRTIRVTAMVGAAA
HHHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNALNLRELFSVSNLRQLSAPILIVMILSMMVLPLPVFLLDVFFTFNIAVSVMVMLVAMY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKPLDFSVFPTVLLVTTLLRLSLNVASTRIVLLNGHSGPDAAGKVIEAFGHFLVGGNTA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHEECCCHH
VGIVVFVILTIINFVVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIDEKTAKAR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
RKEIAQEADFYGAMDGASKFVRGDAVAGILILVINIIGGLFVGVVQHNMAAGDAAHTYTL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEE
LTIGDGLVAQIPALIISVAAGLVVSRVGDEGDIGGLVIGQLFSNPQVLALTAGIIGVLGL
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHH
IPGMPNFVFLLLAAGLGWLAWSRNRKLMEPESVAQTQAAAAQAAAAAPQAEAQEASWNDV
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
APVDVLGLEVGYRLIPMVDKGQDGELLKRIRGLRKKFAQEVGFLSAPVHIRDNLELKPNA
CCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCE
YRIALKGVEIGSGEAYPGQYLAINPGRVSGPMSGRETKDPAFGLPAYWIDAGSREQAHGL
EEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
GYTVVDASTVVATHLNHLILNHAAELLGRQETQALLDHIGKESPKLVDDLVPKLLPISAV
CEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
QRVLQNLLDEGVNIRDMRTIIEVLAEFAPRNQDPVELTSKVREALGRAIIQGLFPGTAEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
QVMALEPSLERILMQAMSASGEGGAIEPGLADTLLRQTAQIAQRQEDIGLPPVLLVPAPL
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHH
RMLLSRFLRRAVPTLKVISNAEVPESRTIRVTAMVGAAA
HHHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]