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The map label for this gene is cysS [H]

Identifier: 119897351

GI number: 119897351

Start: 1139410

End: 1140792

Strand: Direct

Name: cysS [H]

Synonym: azo1060

Alternate gene names: 119897351

Gene position: 1139410-1140792 (Clockwise)

Preceding gene: 119897345

Following gene: 119897356

Centisome position: 26.04

GC content: 66.38

Gene sequence:

>1383_bases
ATGCTCTCGATCCACAACACCCTGTCCCGCAGCAAGGAAGTCTTCCGTCCGATCGAACCCGGCAAGGTCCGCATGTATGT
GTGCGGAATGACGGTGTACGACTACTGCCACCTTGGCCACGCGCGGGTGATGGTGGTGTTCGACATGGTGGCACGCTGGC
TGCGCGCGAGTGGTTTCGATGTCACCTATGTGCGCAACATCACCGATATCGACGACAAGATCATCCGCCGTGCGCAGGAG
AATGGGGAGTCGATCCGCGCGCTGACCGACCGTTTCATCGCGGCGATGCACGAAGACGCGGATGCGCTGGGCGTGCTGCG
CCCGGATCATGAACCGCGCGCGACCGACTATGTGGCCAGCATGCAGAGCCTGATCGAGCGCCTGCACGCCAAGGGTCTTG
CCTACGTCGCCGCCAACCACGACGTGTGCTACGCGGTGCGCAAGTTCGAGGGCTACGGCAAGCTGTCGGGCAAGTCGCTG
GACGAGTTGCGCGCCGGCGAGCGCGTCGAGGTGGCCGGCGAGAAAAAGGACCCGCTCGACTTCGTGCTGTGGAAGCACGC
CAAGGCGGAAGAGCCGGACGAGGCCAAGTGGGCGTCCCCGTGGGGCAGCGGCCGTCCCGGCTGGCACATCGAGTGCTCGG
CGATGAGTTCGGACCTGCTCGGCGAGCATTTCGACATCCACGGCGGCGGCCAGGACCTGCAGTTCCCGCACCACGAGAAC
GAGATCGCGCAGTCGGAAGGCGCGCACGGCCACGCCTTCGTCAATTACTGGATGCACAACGGCTTCGTCCGCGTGGACGA
CGAGAAGATGTCGAAGTCGCTCGGCAACTTCTTCACCATCCGCGACGTGCTCGAAACCTACGATGCGGAAGTGGTCCGTT
TCTTCATCCTGCGCGCCCACTACCGCAGTCCGCTCAATTACTCCGATGCTCACCTGGACGACGCCCGCCAAGCGTTGACG
CGCTTGTATACCGCGCTGCGCTCGGTCGAGGCCGCCCCCGCGGCGGTGGACTGGACCGAAAGCCATGCGCTGCGCTTCAG
GGCGGCGATGGACGACGATTTCAATACCGCGGAGGCGTTGGCGGTGTTGTTCGAACTGGCGAACGAGGTCAACCGCGGCC
GCGACCCGCTGCTGGCCGCGCAGCTGAAGGCGCTCGGCGCGGTGCTCGGGCTGCTGGAGCGCGACCCGGTCGCTTTCCTG
CAGGGCAGCACGCCCGCTGCGAGCGGGCTGGGGCCGGAAGACATCGAGGCCCGGATAGCGGCGCGCGCGGCGGCCAAGAA
GGCCAAGGATTTCGCCGAGGCCGACCGGATTCGCGCCGAACTGCTGGCCGCGGGCATCGTTCTTGAGGACGGCGCGGGAG
GCACCACCTGGCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
TACTCCTACAATCCGACGTCGTACGGCCGCCGAGTTAGGCGTCGGCAAGGCGGGGCCACCAGGCACCCGCTTTTTTTGTG
CGATTTTTTTGGTAAAGCGC

Downstream 100 bases:

>100_bases
AAACGACAACGGCCCCGCTGGACGGGGCCGTTGTCATGGTGCGTGGTGTAGTCGCGGTGCGCCGTCAGCGGGTGAAGTTG
CCGCGGCTGATCACCGTCAG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLSIHNTLSRSKEVFRPIEPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFDVTYVRNITDIDDKIIRRAQE
NGESIRALTDRFIAAMHEDADALGVLRPDHEPRATDYVASMQSLIERLHAKGLAYVAANHDVCYAVRKFEGYGKLSGKSL
DELRAGERVEVAGEKKDPLDFVLWKHAKAEEPDEAKWASPWGSGRPGWHIECSAMSSDLLGEHFDIHGGGQDLQFPHHEN
EIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLETYDAEVVRFFILRAHYRSPLNYSDAHLDDARQALT
RLYTALRSVEAAPAAVDWTESHALRFRAAMDDDFNTAEALAVLFELANEVNRGRDPLLAAQLKALGAVLGLLERDPVAFL
QGSTPAASGLGPEDIEARIAARAAAKKAKDFAEADRIRAELLAAGIVLEDGAGGTTWRRA

Sequences:

>Translated_460_residues
MLSIHNTLSRSKEVFRPIEPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFDVTYVRNITDIDDKIIRRAQE
NGESIRALTDRFIAAMHEDADALGVLRPDHEPRATDYVASMQSLIERLHAKGLAYVAANHDVCYAVRKFEGYGKLSGKSL
DELRAGERVEVAGEKKDPLDFVLWKHAKAEEPDEAKWASPWGSGRPGWHIECSAMSSDLLGEHFDIHGGGQDLQFPHHEN
EIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLETYDAEVVRFFILRAHYRSPLNYSDAHLDDARQALT
RLYTALRSVEAAPAAVDWTESHALRFRAAMDDDFNTAEALAVLFELANEVNRGRDPLLAAQLKALGAVLGLLERDPVAFL
QGSTPAASGLGPEDIEARIAARAAAKKAKDFAEADRIRAELLAAGIVLEDGAGGTTWRRA
>Mature_460_residues
MLSIHNTLSRSKEVFRPIEPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFDVTYVRNITDIDDKIIRRAQE
NGESIRALTDRFIAAMHEDADALGVLRPDHEPRATDYVASMQSLIERLHAKGLAYVAANHDVCYAVRKFEGYGKLSGKSL
DELRAGERVEVAGEKKDPLDFVLWKHAKAEEPDEAKWASPWGSGRPGWHIECSAMSSDLLGEHFDIHGGGQDLQFPHHEN
EIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLETYDAEVVRFFILRAHYRSPLNYSDAHLDDARQALT
RLYTALRSVEAAPAAVDWTESHALRFRAAMDDDFNTAEALAVLFELANEVNRGRDPLLAAQLKALGAVLGLLERDPVAFL
QGSTPAASGLGPEDIEARIAARAAAKKAKDFAEADRIRAELLAAGIVLEDGAGGTTWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=391, Percent_Identity=39.8976982097187, Blast_Score=245, Evalue=7e-65,
Organism=Homo sapiens, GI21269877, Length=307, Percent_Identity=35.8306188925081, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI10835051, Length=319, Percent_Identity=35.423197492163, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI62240992, Length=319, Percent_Identity=35.423197492163, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI303304987, Length=307, Percent_Identity=35.8306188925081, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1786737, Length=467, Percent_Identity=59.9571734475375, Blast_Score=523, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17509795, Length=238, Percent_Identity=38.655462184874, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17509797, Length=238, Percent_Identity=38.655462184874, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324082, Length=331, Percent_Identity=31.7220543806647, Blast_Score=173, Evalue=4e-44,
Organism=Drosophila melanogaster, GI19922218, Length=507, Percent_Identity=33.9250493096647, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI19922364, Length=332, Percent_Identity=36.144578313253, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51171; Mature: 51171

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIHNTLSRSKEVFRPIEPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFD
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
VTYVRNITDIDDKIIRRAQENGESIRALTDRFIAAMHEDADALGVLRPDHEPRATDYVAS
EEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHH
MQSLIERLHAKGLAYVAANHDVCYAVRKFEGYGKLSGKSLDELRAGERVEVAGEKKDPLD
HHHHHHHHHHCCEEEEECCCCCEEHHHHHCCCCCCCCCCHHHHHCCCEEEECCCCCCCHH
FVLWKHAKAEEPDEAKWASPWGSGRPGWHIECSAMSSDLLGEHFDIHGGGQDLQFPHHEN
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCEECCCCCCCCCCCCCC
EIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLETYDAEVVRFFILRAH
HHHHCCCCCCHHHHEEHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YRSPLNYSDAHLDDARQALTRLYTALRSVEAAPAAVDWTESHALRFRAAMDDDFNTAEAL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHEEEEECCCCCCCHHHHH
AVLFELANEVNRGRDPLLAAQLKALGAVLGLLERDPVAFLQGSTPAASGLGPEDIEARIA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHH
ARAAAKKAKDFAEADRIRAELLAAGIVLEDGAGGTTWRRA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLSIHNTLSRSKEVFRPIEPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFD
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
VTYVRNITDIDDKIIRRAQENGESIRALTDRFIAAMHEDADALGVLRPDHEPRATDYVAS
EEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHH
MQSLIERLHAKGLAYVAANHDVCYAVRKFEGYGKLSGKSLDELRAGERVEVAGEKKDPLD
HHHHHHHHHHCCEEEEECCCCCEEHHHHHCCCCCCCCCCHHHHHCCCEEEECCCCCCCHH
FVLWKHAKAEEPDEAKWASPWGSGRPGWHIECSAMSSDLLGEHFDIHGGGQDLQFPHHEN
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCEECCCCCCCCCCCCCC
EIAQSEGAHGHAFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLETYDAEVVRFFILRAH
HHHHCCCCCCHHHHEEHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YRSPLNYSDAHLDDARQALTRLYTALRSVEAAPAAVDWTESHALRFRAAMDDDFNTAEAL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHEEEEECCCCCCCHHHHH
AVLFELANEVNRGRDPLLAAQLKALGAVLGLLERDPVAFLQGSTPAASGLGPEDIEARIA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHH
ARAAAKKAKDFAEADRIRAELLAAGIVLEDGAGGTTWRRA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA