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The map label for this gene is tas [H]

Identifier: 119897301

GI number: 119897301

Start: 1086606

End: 1087658

Strand: Direct

Name: tas [H]

Synonym: azo1010

Alternate gene names: 119897301

Gene position: 1086606-1087658 (Clockwise)

Preceding gene: 119897297

Following gene: 119897303

Centisome position: 24.83

GC content: 67.9

Gene sequence:

>1053_bases
ATGCTGCAGCGTTCCATGGAATACCGCGTACTGGGCCGCAACGGCCCGCGTGTCTCTGCGATCTGCCTCGGCACCATGAC
CTTCGGCCAGCAGAACAGCGAGGCCGAGGCGCACGAGCAGCTCGACTTCGCCCTTGCCCAAGGCATCAATTTCATCGACA
CGGCCGAGATGTACCCCGTGCCCGCGCGGGCGGAAACCAGCGGCGCCACCGAGCGGTTCGTCGGCAGCTGGCTGGCGCGC
CAGGCGCGCGAGCGCATCGTGTTGGCGACCAAGGTGGCGGGGCCGGCGCGCAGCCTGGGCTGGATCCGCGGAGGCCCGCT
CGCGCTCGACCGCGCCAACATCCGCGAGGCGGTCGAGGGCAGCCTGCGCCGCCTGCGCACCGACTATATCGATCTTTATC
AACTGCACTGGCCGGAACGCAACCAGCCGATGTTCGGCCAGTGGCAGTACGAGCCGGACAAGGAGCGCGAATGCACATCG
ATTCGCGCCCAGCTCGAGGCGCTGGCCGAACTGGTGGACGAGGGCAAGGTGCGCTACGTCGGCCTGTCCAACGAGCATCC
GTGGGGCGTGATGGAGTTCGTGCGCCTGGCCGCGCTGCACGGCTTGCCGCGGGTGGTGTCGACGCAGAACGCTTACAGCC
TCCTCAATCGTGTGTTCGAGTACGGCCTGGCCGAAGTCTGCCACCGCGAGTCGGTGGGTCTGCTGGCGTACTCGCCGCTG
GCGTTCGGGCACCTGACCGGCAAGTACCTCGCCGATCCGCAGGCGCCGGGCAGGCTGAGCTTGTTCGAGCAGTTCGGCCA
GCGCTACGGCAAACCCAATGTGGTGCCGGCCGCTCGCGCCTACGCGGAACTTGCCGCCGAGCGCGGGCTGACGCCCGCGC
AGCTCGCGCTCGTCTTCACCTATCGACGGCCGTGCGTGGCGAGCACCATCATCGGTGCGACGACGATGGCGCAACTGAAG
GAAAACCTGTCAGCGTGGGATGTGCCGCTGGATGCGGAGCTGGTGTCTGCGATCGACGCCATCCACCTGCGCTACACCAA
TCCGGCGCCCTGA

Upstream 100 bases:

>100_bases
TGCTGCAGTATCATGCTGCGAAGCGGCGCATCATAAGGTGCCGCGCCACGGCAGGCGAGTGTCGCCAGTCGGTTTTATGG
CAACAGGAGATCCGTCCCCG

Downstream 100 bases:

>100_bases
CGCGCCTTCAGTGCTGGGCGGCCCGCGCCGCGGCGGGCGCTTCCGCCGCTTGGGCGGGAGCCGCCTTGGGCTGCGGTGGC
ACCTGGGGCAGCTGCGACGG

Product: oxidoreductase Tas

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MLQRSMEYRVLGRNGPRVSAICLGTMTFGQQNSEAEAHEQLDFALAQGINFIDTAEMYPVPARAETSGATERFVGSWLAR
QARERIVLATKVAGPARSLGWIRGGPLALDRANIREAVEGSLRRLRTDYIDLYQLHWPERNQPMFGQWQYEPDKERECTS
IRAQLEALAELVDEGKVRYVGLSNEHPWGVMEFVRLAALHGLPRVVSTQNAYSLLNRVFEYGLAEVCHRESVGLLAYSPL
AFGHLTGKYLADPQAPGRLSLFEQFGQRYGKPNVVPAARAYAELAAERGLTPAQLALVFTYRRPCVASTIIGATTMAQLK
ENLSAWDVPLDAELVSAIDAIHLRYTNPAP

Sequences:

>Translated_350_residues
MLQRSMEYRVLGRNGPRVSAICLGTMTFGQQNSEAEAHEQLDFALAQGINFIDTAEMYPVPARAETSGATERFVGSWLAR
QARERIVLATKVAGPARSLGWIRGGPLALDRANIREAVEGSLRRLRTDYIDLYQLHWPERNQPMFGQWQYEPDKERECTS
IRAQLEALAELVDEGKVRYVGLSNEHPWGVMEFVRLAALHGLPRVVSTQNAYSLLNRVFEYGLAEVCHRESVGLLAYSPL
AFGHLTGKYLADPQAPGRLSLFEQFGQRYGKPNVVPAARAYAELAAERGLTPAQLALVFTYRRPCVASTIIGATTMAQLK
ENLSAWDVPLDAELVSAIDAIHLRYTNPAP
>Mature_350_residues
MLQRSMEYRVLGRNGPRVSAICLGTMTFGQQNSEAEAHEQLDFALAQGINFIDTAEMYPVPARAETSGATERFVGSWLAR
QARERIVLATKVAGPARSLGWIRGGPLALDRANIREAVEGSLRRLRTDYIDLYQLHWPERNQPMFGQWQYEPDKERECTS
IRAQLEALAELVDEGKVRYVGLSNEHPWGVMEFVRLAALHGLPRVVSTQNAYSLLNRVFEYGLAEVCHRESVGLLAYSPL
AFGHLTGKYLADPQAPGRLSLFEQFGQRYGKPNVVPAARAYAELAAERGLTPAQLALVFTYRRPCVASTIIGATTMAQLK
ENLSAWDVPLDAELVSAIDAIHLRYTNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=352, Percent_Identity=31.25, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436962, Length=349, Percent_Identity=31.2320916905444, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436969, Length=352, Percent_Identity=30.6818181818182, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=349, Percent_Identity=30.945558739255, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4504825, Length=350, Percent_Identity=30.5714285714286, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436971, Length=355, Percent_Identity=30.7042253521127, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41327764, Length=348, Percent_Identity=29.0229885057471, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223718702, Length=356, Percent_Identity=28.0898876404494, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI291291012, Length=260, Percent_Identity=26.5384615384615, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI41152114, Length=355, Percent_Identity=28.169014084507, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=51.8731988472622, Blast_Score=344, Evalue=4e-96,
Organism=Escherichia coli, GI87081735, Length=347, Percent_Identity=33.4293948126801, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=30.7462686567164, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788070, Length=341, Percent_Identity=29.9120234604106, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=337, Percent_Identity=28.486646884273, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=348, Percent_Identity=27.5862068965517, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=321, Percent_Identity=26.791277258567, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=354, Percent_Identity=24.5762711864407, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=343, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=268, Percent_Identity=24.6268656716418, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321052, Length=142, Percent_Identity=35.2112676056338, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646155, Length=336, Percent_Identity=30.0595238095238, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646159, Length=343, Percent_Identity=26.2390670553936, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38942; Mature: 38942

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRSMEYRVLGRNGPRVSAICLGTMTFGQQNSEAEAHEQLDFALAQGINFIDTAEMYPV
CCCCCCCEEEECCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PARAETSGATERFVGSWLARQARERIVLATKVAGPARSLGWIRGGPLALDRANIREAVEG
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCCCEEECHHHHHHHHHH
SLRRLRTDYIDLYQLHWPERNQPMFGQWQYEPDKERECTSIRAQLEALAELVDEGKVRYV
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
GLSNEHPWGVMEFVRLAALHGLPRVVSTQNAYSLLNRVFEYGLAEVCHRESVGLLAYSPL
ECCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
AFGHLTGKYLADPQAPGRLSLFEQFGQRYGKPNVVPAARAYAELAAERGLTPAQLALVFT
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
YRRPCVASTIIGATTMAQLKENLSAWDVPLDAELVSAIDAIHLRYTNPAP
HCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHEEEECCCCC
>Mature Secondary Structure
MLQRSMEYRVLGRNGPRVSAICLGTMTFGQQNSEAEAHEQLDFALAQGINFIDTAEMYPV
CCCCCCCEEEECCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PARAETSGATERFVGSWLARQARERIVLATKVAGPARSLGWIRGGPLALDRANIREAVEG
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCCCEEECHHHHHHHHHH
SLRRLRTDYIDLYQLHWPERNQPMFGQWQYEPDKERECTSIRAQLEALAELVDEGKVRYV
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
GLSNEHPWGVMEFVRLAALHGLPRVVSTQNAYSLLNRVFEYGLAEVCHRESVGLLAYSPL
ECCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
AFGHLTGKYLADPQAPGRLSLFEQFGQRYGKPNVVPAARAYAELAAERGLTPAQLALVFT
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
YRRPCVASTIIGATTMAQLKENLSAWDVPLDAELVSAIDAIHLRYTNPAP
HCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]