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The map label for this gene is hemX [H]

Identifier: 119897286

GI number: 119897286

Start: 1069486

End: 1070682

Strand: Direct

Name: hemX [H]

Synonym: azo0995

Alternate gene names: 119897286

Gene position: 1069486-1070682 (Clockwise)

Preceding gene: 119897285

Following gene: 119897287

Centisome position: 24.44

GC content: 72.43

Gene sequence:

>1197_bases
ATGAACGAAGAAACTCCCGCGCTCACCTCGTCCCCGGCCGCCGCGCAGCCGGCCGCCTCCGTAGAACCTCCCCCGTCGGA
CCCGCGTCCGGCCGCCCCGTCCCGCTCATCGGGCGCCAGCGGCTGGGCGGTGCTCCTTGCCGTGCTCGCGCTTGGCGGCG
CCGGGCTGGCCGGCTGGCAGGCGTGGGAGACCCGGGCGCGGGTCGGCGAACTGCGCCAGGAGCTGGCGAGCCGCCTCAAC
GCGGGCGACACCGTGGCAGCCGAGGCACGCGCGCTTGCGCGCCAGCAGCAGGAGGCGATGGCCGCGCTGCAGGGCCGGGT
CGGCGCGCTTGCGGCGCAGATCGAGGCGACCGAAGGGCAGGCCGCGGCCCTGGAGGCGCTCTATCAGGAGTTTTCCCGCT
CGCGCGAAGATCGCGTGGTGGCGGAAGTGGAACAGGCGGTCAATGTGGCGGCCCAGCAGCTTCAGCTCGCCGGCAACATC
GAGGCTGCACTGATCGCGCTGCAGGGCGCGGAGGCGCGGCTGGCGTTGCAGGACAAGGGCCAGCTGGCAGTGCTGCGGCG
TGCGCTCGCCAAGGATATCGAGCAGCTCAAGCTGCAGCCCGAGGTGGATGTCGGCGGTATCGCACTGCGCCTCGAGCGTC
TGCTGGAACGCGGCGATGCGCTGCCGCTCGCCTTCGAAAGCCAGCCGCCCGCCAATGCCGAGCACGGCGGGGAACAGGCG
GCAGCGGTTGAACCCGGGCGCCTCAATGTGGCGCTGGCCTTCATCACCGAGCTGGGGCGCGACGTGTGGCGCGAACTGCG
TTCGCTGGTCCGTGTCGAGCGGCTGGATCAGTCCGAACCGGTGCTGCTGGCCCCGGCGCAGAGCACTTTCCTGCGCGAAA
ACCTCAAGATCCGCCTGCTCACGGCGCGGCTGGCCTTGCTCGCGCGCGACGGCCGCACCTATGCCGCCGACCTCGCCCAG
GCGCGCAGCTGGATGGAGCGGTTCTTCGATACACGCGACGAACGTGTCCGCGAAGCGATCGGCGAACTCAAGGCGCTCGA
GGCGATGTCGGTCGGCGACGAACGCCCGGCCCTGACCGAGAGCTTCGCCGCGCTGCGGGTGCTGCAGACCCGCGCCGGCG
AACCCCGCACGCCCGCTGTTGCGGCAGAACCGGCCAGGCCGGCCAATGGTGGTCGCGCGCCGGCCCCGCAGCGCTGA

Upstream 100 bases:

>100_bases
GCACGCCCGCGCCGCCGGCTTCGATCGCGTCGAGGAAACCCCGCCCGGCGATGACGGCCTGCTGGAGACGCTGGTCCGCC
ACTTTGGTTAAACTCTCGGC

Downstream 100 bases:

>100_bases
GGAACCGGCCCCATGCGCGCCCTGTTCTGGCTGATCGGCATCTTTGCCACCGCGGTGGGGCTGGCGATGCTTGCCCGCCT
CAATGACGGCTACGTGCTGG

Product: uroporphyrin-III C-methyltransferase

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNEETPALTSSPAAAQPAASVEPPPSDPRPAAPSRSSGASGWAVLLAVLALGGAGLAGWQAWETRARVGELRQELASRLN
AGDTVAAEARALARQQQEAMAALQGRVGALAAQIEATEGQAAALEALYQEFSRSREDRVVAEVEQAVNVAAQQLQLAGNI
EAALIALQGAEARLALQDKGQLAVLRRALAKDIEQLKLQPEVDVGGIALRLERLLERGDALPLAFESQPPANAEHGGEQA
AAVEPGRLNVALAFITELGRDVWRELRSLVRVERLDQSEPVLLAPAQSTFLRENLKIRLLTARLALLARDGRTYAADLAQ
ARSWMERFFDTRDERVREAIGELKALEAMSVGDERPALTESFAALRVLQTRAGEPRTPAVAAEPARPANGGRAPAPQR

Sequences:

>Translated_398_residues
MNEETPALTSSPAAAQPAASVEPPPSDPRPAAPSRSSGASGWAVLLAVLALGGAGLAGWQAWETRARVGELRQELASRLN
AGDTVAAEARALARQQQEAMAALQGRVGALAAQIEATEGQAAALEALYQEFSRSREDRVVAEVEQAVNVAAQQLQLAGNI
EAALIALQGAEARLALQDKGQLAVLRRALAKDIEQLKLQPEVDVGGIALRLERLLERGDALPLAFESQPPANAEHGGEQA
AAVEPGRLNVALAFITELGRDVWRELRSLVRVERLDQSEPVLLAPAQSTFLRENLKIRLLTARLALLARDGRTYAADLAQ
ARSWMERFFDTRDERVREAIGELKALEAMSVGDERPALTESFAALRVLQTRAGEPRTPAVAAEPARPANGGRAPAPQR
>Mature_398_residues
MNEETPALTSSPAAAQPAASVEPPPSDPRPAAPSRSSGASGWAVLLAVLALGGAGLAGWQAWETRARVGELRQELASRLN
AGDTVAAEARALARQQQEAMAALQGRVGALAAQIEATEGQAAALEALYQEFSRSREDRVVAEVEQAVNVAAQQLQLAGNI
EAALIALQGAEARLALQDKGQLAVLRRALAKDIEQLKLQPEVDVGGIALRLERLLERGDALPLAFESQPPANAEHGGEQA
AAVEPGRLNVALAFITELGRDVWRELRSLVRVERLDQSEPVLLAPAQSTFLRENLKIRLLTARLALLARDGRTYAADLAQ
ARSWMERFFDTRDERVREAIGELKALEAMSVGDERPALTESFAALRVLQTRAGEPRTPAVAAEPARPANGGRAPAPQR

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=338, Percent_Identity=26.6272189349112, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 42486; Mature: 42486

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEETPALTSSPAAAQPAASVEPPPSDPRPAAPSRSSGASGWAVLLAVLALGGAGLAGWQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
AWETRARVGELRQELASRLNAGDTVAAEARALARQQQEAMAALQGRVGALAAQIEATEGQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAALEALYQEFSRSREDRVVAEVEQAVNVAAQQLQLAGNIEAALIALQGAEARLALQDKG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCC
QLAVLRRALAKDIEQLKLQPEVDVGGIALRLERLLERGDALPLAFESQPPANAEHGGEQA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AAVEPGRLNVALAFITELGRDVWRELRSLVRVERLDQSEPVLLAPAQSTFLRENLKIRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCEEHH
TARLALLARDGRTYAADLAQARSWMERFFDTRDERVREAIGELKALEAMSVGDERPALTE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SFAALRVLQTRAGEPRTPAVAAEPARPANGGRAPAPQR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNEETPALTSSPAAAQPAASVEPPPSDPRPAAPSRSSGASGWAVLLAVLALGGAGLAGWQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
AWETRARVGELRQELASRLNAGDTVAAEARALARQQQEAMAALQGRVGALAAQIEATEGQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AAALEALYQEFSRSREDRVVAEVEQAVNVAAQQLQLAGNIEAALIALQGAEARLALQDKG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCC
QLAVLRRALAKDIEQLKLQPEVDVGGIALRLERLLERGDALPLAFESQPPANAEHGGEQA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AAVEPGRLNVALAFITELGRDVWRELRSLVRVERLDQSEPVLLAPAQSTFLRENLKIRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCEEHH
TARLALLARDGRTYAADLAQARSWMERFFDTRDERVREAIGELKALEAMSVGDERPALTE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SFAALRVLQTRAGEPRTPAVAAEPARPANGGRAPAPQR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]