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The map label for this gene is tctD [H]

Identifier: 119897270

GI number: 119897270

Start: 1052174

End: 1052845

Strand: Reverse

Name: tctD [H]

Synonym: azo0979

Alternate gene names: 119897270

Gene position: 1052845-1052174 (Counterclockwise)

Preceding gene: 119897275

Following gene: 119897258

Centisome position: 24.06

GC content: 69.2

Gene sequence:

>672_bases
ATGCACATCCTGGTGGCGGACGACGACGACCGCTTCACGCGCCCGCTTGCGGCCTTCCTGCGCACGCGGGGCGATCAGGT
CACCGTTGCGGTCGACGGCACCGCGGCGGACGGCCTCCTGCAACACAGCCCGTTCGACTTCGCCCTAGTGGAAGTCAACC
TCGCAGGCGTGAACGGATACGAGCTGGTGCGGCGTTTGCGAAGCCGGCGGCAGACAACCCCCGTGATCTTCATCAGTGCC
CGCCAGGCGCTGGAGGACCGCATCCACGGTCTCGACCTTGGCGCCGACGATTATGTGGTCAAGCCGGCGGAGATTTCCGA
GATCACCGCGCGGATGCGCGCGGTGCTGCGCCGCGGGCCCTACCGGATCGGCGACGAGATGCGCTTCGGGCCGATCATGC
TGGACGCCGACGGCCGGCTCGCCTCCCTCAACGGACAGGCACTGCCGCTCACCGGACGGGAATGGGAGATTCTCGAAGCA
CTGGTCGCGGCCGATGGGCGTACGGTCGCGAAGGACCGCCTGCAGGCGGACAGCGGCGGCAATGCCGCCGAGGTGTACAT
CTCCCGCCTCCGCCCCAGACTGGAACCCGCGGGGGTACTGATCCGTACCGTGCGCGGCTTCGGCTACCGGCTGGAACTCC
AGGCTGTCGCCGGCGAGGACGCGCCCGGCTGA

Upstream 100 bases:

>100_bases
AGCTATCGCCAGACGTCAAGCATGATTTCATTCCCGGCCTCGAAAGGACGGCGGCGAAGGCTTTCCGCCTCATGCGGGAA
CACTCCCAAGGCAGAACACG

Downstream 100 bases:

>100_bases
GTCGCTGCCGACCAGCTTCACGCGACCGGGAAGCAAAAAAGGAAAAAGCGGAGATCACCCGATCTCCGCTTTTTCTTTCC
GCAAGGGCCCGGCGCAAACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MHILVADDDDRFTRPLAAFLRTRGDQVTVAVDGTAADGLLQHSPFDFALVEVNLAGVNGYELVRRLRSRRQTTPVIFISA
RQALEDRIHGLDLGADDYVVKPAEISEITARMRAVLRRGPYRIGDEMRFGPIMLDADGRLASLNGQALPLTGREWEILEA
LVAADGRTVAKDRLQADSGGNAAEVYISRLRPRLEPAGVLIRTVRGFGYRLELQAVAGEDAPG

Sequences:

>Translated_223_residues
MHILVADDDDRFTRPLAAFLRTRGDQVTVAVDGTAADGLLQHSPFDFALVEVNLAGVNGYELVRRLRSRRQTTPVIFISA
RQALEDRIHGLDLGADDYVVKPAEISEITARMRAVLRRGPYRIGDEMRFGPIMLDADGRLASLNGQALPLTGREWEILEA
LVAADGRTVAKDRLQADSGGNAAEVYISRLRPRLEPAGVLIRTVRGFGYRLELQAVAGEDAPG
>Mature_223_residues
MHILVADDDDRFTRPLAAFLRTRGDQVTVAVDGTAADGLLQHSPFDFALVEVNLAGVNGYELVRRLRSRRQTTPVIFISA
RQALEDRIHGLDLGADDYVVKPAEISEITARMRAVLRRGPYRIGDEMRFGPIMLDADGRLASLNGQALPLTGREWEILEA
LVAADGRTVAKDRLQADSGGNAAEVYISRLRPRLEPAGVLIRTVRGFGYRLELQAVAGEDAPG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=33.9449541284404, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.6322869955157, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=32.8888888888889, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.4801762114537, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=35.1111111111111, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=33.4841628959276, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.2222222222222, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=34.6666666666667, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=29.8642533936652, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=29.2035398230088, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790860, Length=181, Percent_Identity=33.1491712707182, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=31.304347826087, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=27.0742358078603, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=29.8245614035088, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24430; Mature: 24430

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILVADDDDRFTRPLAAFLRTRGDQVTVAVDGTAADGLLQHSPFDFALVEVNLAGVNGY
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCCEEEEEEEEECCCHH
ELVRRLRSRRQTTPVIFISARQALEDRIHGLDLGADDYVVKPAEISEITARMRAVLRRGP
HHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCC
YRIGDEMRFGPIMLDADGRLASLNGQALPLTGREWEILEALVAADGRTVAKDRLQADSGG
CCCCCCCEECCEEECCCCCEEECCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCCCC
NAAEVYISRLRPRLEPAGVLIRTVRGFGYRLELQAVAGEDAPG
CHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MHILVADDDDRFTRPLAAFLRTRGDQVTVAVDGTAADGLLQHSPFDFALVEVNLAGVNGY
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCCEEEEEEEEECCCHH
ELVRRLRSRRQTTPVIFISARQALEDRIHGLDLGADDYVVKPAEISEITARMRAVLRRGP
HHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCC
YRIGDEMRFGPIMLDADGRLASLNGQALPLTGREWEILEALVAADGRTVAKDRLQADSGG
CCCCCCCEECCEEECCCCCEEECCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCCCC
NAAEVYISRLRPRLEPAGVLIRTVRGFGYRLELQAVAGEDAPG
CHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]