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The map label for this gene is cbbF

Identifier: 119897259

GI number: 119897259

Start: 1039663

End: 1040664

Strand: Direct

Name: cbbF

Synonym: azo0968

Alternate gene names: 119897259

Gene position: 1039663-1040664 (Clockwise)

Preceding gene: 119897257

Following gene: 119897260

Centisome position: 23.76

GC content: 64.67

Gene sequence:

>1002_bases
ATGCGTCGTGTGACACTTACCCAATTCCTCATCGAGCAGCAGCGTGCAGGGCGCGTCTCGGCCGATCTGCGTCTGCTGAT
CGAGGTCGTCGCACGCGCGGTGAAGGCGATCAGCGTCAATGTCTCGAAGGGCGCACTGGCCGGCGTGCTGGGCGAGGCGG
GCACCGACAACGTGCAGGGCGAAGCGCAGAAGAAGCTCGATGTCATTGCCAACGAAATCCTGCTGCAGGCCAATGAGTGG
GGCGGGCACCTGGCGGCGATGGCGTCCGAAGAGGTCGAGACGGTGCACCAGATCCCGTTCGACTATCCGAAGGGCGGCTA
TCTGCTGCTGTTCGATCCGCTCGACGGTTCGTCCAATATCGACGTCAACATTTCGGTCGGCACCATCTTCTCGGTGCTGC
GTTTTCCCGAAGGCGAGGCCGAGCCGACCGAGCAGAGCTTCATGCAGCCGGGCCGCGAGCAGGTCGCTGCGGGCTATGCG
GTGTATGGACCGTCGACCCAGCTGGTGCTCACCGTGGGCCACGGCGTGCATGCGTTTACGCTGGACCGCGAGATGGGAAG
CTTCATCTACACCCACCCCTTCATGACCATTCCCGACGACACCCACGAGTTCGCGATCAACGCCTCCAACGCCCGCTTCT
GGGAGGAGCCGGTGCAGCGCTACGTGGGTGAACTCCAGGCGGGCAAGACCGGCCCGCGCGGCAAGGACTTCAACATGCGC
TGGGTGGCGTCGATGGTGGCCGACGTGCACCGCATCCTCACCCGTGGCGGCATCTTCATGTATCCGCTCGATGAGAAGTG
CCGCGCGCAGGGCGGCAAGCTGCGCCTGATGTACGAGGCCAATCCGATGGCAATGCTGGTGGAACAAGCCGGCGGCGCGG
CCACCACCGGGCGCGAGCGCATCCTGGACCTGATGCCGACCAAGCTTCACCAGCGTGTGCCGGTGATCCTCGGTTCGCGC
AACGAGGTCGAGCGTGTGACCGCCTATCACCGCGAGTCCTGA

Upstream 100 bases:

>100_bases
CGCCCCGTGCCCACCCTGGGGCGAGGCGGACCGTGCGTATCTCACGCGGAAGCGGGATAATCCGGCGGTTTCTGATCATT
CATCGGCAAGGGAGCCATCG

Downstream 100 bases:

>100_bases
CGGGGCCGGCGGTGCGCTGCAGCCTGCGCCTCGCCACAGCGGTCGTGCTGCTGTGTGCTGCGGGTGTGGCGGGCGCGCAG
TCGCCGCTGGAGATCGAACT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRRVTLTQFLIEQQRAGRVSADLRLLIEVVARAVKAISVNVSKGALAGVLGEAGTDNVQGEAQKKLDVIANEILLQANEW
GGHLAAMASEEVETVHQIPFDYPKGGYLLLFDPLDGSSNIDVNISVGTIFSVLRFPEGEAEPTEQSFMQPGREQVAAGYA
VYGPSTQLVLTVGHGVHAFTLDREMGSFIYTHPFMTIPDDTHEFAINASNARFWEEPVQRYVGELQAGKTGPRGKDFNMR
WVASMVADVHRILTRGGIFMYPLDEKCRAQGGKLRLMYEANPMAMLVEQAGGAATTGRERILDLMPTKLHQRVPVILGSR
NEVERVTAYHRES

Sequences:

>Translated_333_residues
MRRVTLTQFLIEQQRAGRVSADLRLLIEVVARAVKAISVNVSKGALAGVLGEAGTDNVQGEAQKKLDVIANEILLQANEW
GGHLAAMASEEVETVHQIPFDYPKGGYLLLFDPLDGSSNIDVNISVGTIFSVLRFPEGEAEPTEQSFMQPGREQVAAGYA
VYGPSTQLVLTVGHGVHAFTLDREMGSFIYTHPFMTIPDDTHEFAINASNARFWEEPVQRYVGELQAGKTGPRGKDFNMR
WVASMVADVHRILTRGGIFMYPLDEKCRAQGGKLRLMYEANPMAMLVEQAGGAATTGRERILDLMPTKLHQRVPVILGSR
NEVERVTAYHRES
>Mature_333_residues
MRRVTLTQFLIEQQRAGRVSADLRLLIEVVARAVKAISVNVSKGALAGVLGEAGTDNVQGEAQKKLDVIANEILLQANEW
GGHLAAMASEEVETVHQIPFDYPKGGYLLLFDPLDGSSNIDVNISVGTIFSVLRFPEGEAEPTEQSFMQPGREQVAAGYA
VYGPSTQLVLTVGHGVHAFTLDREMGSFIYTHPFMTIPDDTHEFAINASNARFWEEPVQRYVGELQAGKTGPRGKDFNMR
WVASMVADVHRILTRGGIFMYPLDEKCRAQGGKLRLMYEANPMAMLVEQAGGAATTGRERILDLMPTKLHQRVPVILGSR
NEVERVTAYHRES

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=332, Percent_Identity=44.2771084337349, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI16579888, Length=332, Percent_Identity=44.2771084337349, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI22907028, Length=321, Percent_Identity=41.1214953271028, Blast_Score=242, Evalue=3e-64,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=43.202416918429, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17508131, Length=327, Percent_Identity=43.1192660550459, Blast_Score=269, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323409, Length=324, Percent_Identity=41.9753086419753, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI19921562, Length=329, Percent_Identity=43.161094224924, Blast_Score=257, Evalue=7e-69,
Organism=Drosophila melanogaster, GI45550998, Length=329, Percent_Identity=43.161094224924, Blast_Score=257, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_AZOSB (A1K430)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932472.1
- ProteinModelPortal:   A1K430
- SMR:   A1K430
- STRING:   A1K430
- GeneID:   4608578
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0968
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   A1K430
- ProtClustDB:   PRK09293
- BioCyc:   ASP62928:AZO0968-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36710; Mature: 36710

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00124 FBPASE

Important sites: BINDING 207-207 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVTLTQFLIEQQRAGRVSADLRLLIEVVARAVKAISVNVSKGALAGVLGEAGTDNVQG
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCCC
EAQKKLDVIANEILLQANEWGGHLAAMASEEVETVHQIPFDYPKGGYLLLFDPLDGSSNI
HHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCE
DVNISVGTIFSVLRFPEGEAEPTEQSFMQPGREQVAAGYAVYGPSTQLVLTVGHGVHAFT
EEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHCCEEEECCCCEEEEEECCCEEEEE
LDREMGSFIYTHPFMTIPDDTHEFAINASNARFWEEPVQRYVGELQAGKTGPRGKDFNMR
ECHHHCCEEEECCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
WVASMVADVHRILTRGGIFMYPLDEKCRAQGGKLRLMYEANPMAMLVEQAGGAATTGRER
HHHHHHHHHHHHHHHCCEEEEECCHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCHHHH
ILDLMPTKLHQRVPVILGSRNEVERVTAYHRES
HHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRRVTLTQFLIEQQRAGRVSADLRLLIEVVARAVKAISVNVSKGALAGVLGEAGTDNVQG
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCCCC
EAQKKLDVIANEILLQANEWGGHLAAMASEEVETVHQIPFDYPKGGYLLLFDPLDGSSNI
HHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCE
DVNISVGTIFSVLRFPEGEAEPTEQSFMQPGREQVAAGYAVYGPSTQLVLTVGHGVHAFT
EEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHCCEEEECCCCEEEEEECCCEEEEE
LDREMGSFIYTHPFMTIPDDTHEFAINASNARFWEEPVQRYVGELQAGKTGPRGKDFNMR
ECHHHCCEEEECCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
WVASMVADVHRILTRGGIFMYPLDEKCRAQGGKLRLMYEANPMAMLVEQAGGAATTGRER
HHHHHHHHHHHHHHHCCEEEEECCHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCHHHH
ILDLMPTKLHQRVPVILGSRNEVERVTAYHRES
HHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA