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The map label for this gene is ytfL2 [C]

Identifier: 119897204

GI number: 119897204

Start: 977524

End: 978858

Strand: Reverse

Name: ytfL2 [C]

Synonym: azo0913

Alternate gene names: 119897204

Gene position: 978858-977524 (Counterclockwise)

Preceding gene: 119897208

Following gene: 119897200

Centisome position: 22.37

GC content: 65.47

Gene sequence:

>1335_bases
ATGGAAGTCTTCATCCTCATCGCGCTGATCATTCTCAACGGCGCGTTCGCGATGTCCGAAATCGCCCTCGTCACCGCGCG
TCGCGCCCGTCTTGCCAAGCTGGCCGAAGAGGGCGACGCCTCGGCCGCAGTCGCGATCAAGCTCGGAGAAGAGCCCACCC
GTTTCCTCTCTACGATCCAGATCGGCATCACGTCGATCGGCATCCTCAACGGCATCGTCGGCGAGGCCGCCCTCGCCGCC
CCGCTGGCCGCCTGGCTGCAGGACCTGGGTCTGGCCCAGCGCCCCAGCGAGATCGGCGCCACGGTGCTGGTCGTGATGGT
CATCACCTACATTTCGATCGTGGTGGGCGAACTGGTCCCCAAGCGCGTGGGGCAGCTTAACCCGGAGGCGATCGCGCGCC
TGGTGGCCAAGCCGATGAACACCCTGTCCATCGTCTCGCGCCCCTTCGTCCGCCTGCTGTCGGGATCGACTGCGGTGCTG
CTCCGCATCCTCGGCCAGCGCGACGAAAGCGCGCCGGGCGTGACCGAGGAAGAAATCCACGCGCTGCTCGAAGAGGGTTC
GGTGGCCGGCATCATCGAGAAGAACGAGCACGCGATGGTGCGCAACGTGTTCCGCCTCGACGACCGCCAGATCGGTTCGC
TGATGGTGCCGCGTTCGGATATCGTCTGGCTCGACGTGACCCGTCCGCTGGAATCCAACCTCGCCCGCATGGCCGAATCG
GATCACTCCCGCTTCCCGGTCTGCCGCGGCGGCCTCGACGACATCCTCGGCATCATTTCGTCAAAGCAGCTCTTCAACCA
GACGCTCAAGGGCGGCAAGGCGGATCTGACCCGCCACCTGGAGACGCCGGTCTATGTGCCCGAGTCGCTGACCGGCATGG
AACTGCTGGACCAGTTCCGCGCCTCCAGTTCGCGCATGGTGTTCGTCATCGACGAATACGGCGAAGTGCAAGGCATGGTG
ACGCTGCAGGACGTGATGGAAGCCGTCACCGGGGAGTTCCAGCCGCACCGTCTGGAGGACGCCTGGGCGGTTCAGCGCGA
AGACGGTTCATGGCTGCTCGACGGCCTGATTCCGCTGCCCGAGCTGAAGGATCGCCTTGAGCTGAAGAGCGCTCCGGAAG
AGGAGAAGGGGCGCTATCACACGCTGAGCGGCATGATCATGTGGCTGCTCGGGCGCTTGCCCCGCACGGGGGACGTCACC
GTATGGGAACAGTGGCGGCTGGAGGTGGTTGACCTCGATGGCAAGCGCATCGACAAGATCCTCGCCACCCGGATTTCGAA
TCCCGAAGCGGGCGCGCCGCCGCAACCGGCAACGGACACGCCCGAAGCGCCGTAA

Upstream 100 bases:

>100_bases
GCCGCCACTCGCTCGCACGCGCCCGCACCGGCCCTGCGCAGCAGCCGGAATGCCAGACTGCGCGCGCCGAACCGCGCCGC
ACTGAGCTGACGGAGCGCAC

Downstream 100 bases:

>100_bases
CGCCCCTCAGGCGTGCTGCGCCGGCCGATGCGTGGCCGGCGCAGGCGCAAACCGTGCCACCACGTGGCCGGCCATGCCTT
TGGCGAGTTCCTCCTCCCCA

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MEVFILIALIILNGAFAMSEIALVTARRARLAKLAEEGDASAAVAIKLGEEPTRFLSTIQIGITSIGILNGIVGEAALAA
PLAAWLQDLGLAQRPSEIGATVLVVMVITYISIVVGELVPKRVGQLNPEAIARLVAKPMNTLSIVSRPFVRLLSGSTAVL
LRILGQRDESAPGVTEEEIHALLEEGSVAGIIEKNEHAMVRNVFRLDDRQIGSLMVPRSDIVWLDVTRPLESNLARMAES
DHSRFPVCRGGLDDILGIISSKQLFNQTLKGGKADLTRHLETPVYVPESLTGMELLDQFRASSSRMVFVIDEYGEVQGMV
TLQDVMEAVTGEFQPHRLEDAWAVQREDGSWLLDGLIPLPELKDRLELKSAPEEEKGRYHTLSGMIMWLLGRLPRTGDVT
VWEQWRLEVVDLDGKRIDKILATRISNPEAGAPPQPATDTPEAP

Sequences:

>Translated_444_residues
MEVFILIALIILNGAFAMSEIALVTARRARLAKLAEEGDASAAVAIKLGEEPTRFLSTIQIGITSIGILNGIVGEAALAA
PLAAWLQDLGLAQRPSEIGATVLVVMVITYISIVVGELVPKRVGQLNPEAIARLVAKPMNTLSIVSRPFVRLLSGSTAVL
LRILGQRDESAPGVTEEEIHALLEEGSVAGIIEKNEHAMVRNVFRLDDRQIGSLMVPRSDIVWLDVTRPLESNLARMAES
DHSRFPVCRGGLDDILGIISSKQLFNQTLKGGKADLTRHLETPVYVPESLTGMELLDQFRASSSRMVFVIDEYGEVQGMV
TLQDVMEAVTGEFQPHRLEDAWAVQREDGSWLLDGLIPLPELKDRLELKSAPEEEKGRYHTLSGMIMWLLGRLPRTGDVT
VWEQWRLEVVDLDGKRIDKILATRISNPEAGAPPQPATDTPEAP
>Mature_444_residues
MEVFILIALIILNGAFAMSEIALVTARRARLAKLAEEGDASAAVAIKLGEEPTRFLSTIQIGITSIGILNGIVGEAALAA
PLAAWLQDLGLAQRPSEIGATVLVVMVITYISIVVGELVPKRVGQLNPEAIARLVAKPMNTLSIVSRPFVRLLSGSTAVL
LRILGQRDESAPGVTEEEIHALLEEGSVAGIIEKNEHAMVRNVFRLDDRQIGSLMVPRSDIVWLDVTRPLESNLARMAES
DHSRFPVCRGGLDDILGIISSKQLFNQTLKGGKADLTRHLETPVYVPESLTGMELLDQFRASSSRMVFVIDEYGEVQGMV
TLQDVMEAVTGEFQPHRLEDAWAVQREDGSWLLDGLIPLPELKDRLELKSAPEEEKGRYHTLSGMIMWLLGRLPRTGDVT
VWEQWRLEVVDLDGKRIDKILATRISNPEAGAPPQPATDTPEAP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=368, Percent_Identity=26.6304347826087, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1790664, Length=445, Percent_Identity=33.0337078651685, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=25.7831325301205, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87082033, Length=336, Percent_Identity=28.2738095238095, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1788119, Length=397, Percent_Identity=26.9521410579345, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=268, Percent_Identity=27.6119402985075, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48588; Mature: 48588

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVFILIALIILNGAFAMSEIALVTARRARLAKLAEEGDASAAVAIKLGEEPTRFLSTIQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHH
IGITSIGILNGIVGEAALAAPLAAWLQDLGLAQRPSEIGATVLVVMVITYISIVVGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVGQLNPEAIARLVAKPMNTLSIVSRPFVRLLSGSTAVLLRILGQRDESAPGVTEEEIH
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHH
ALLEEGSVAGIIEKNEHAMVRNVFRLDDRQIGSLMVPRSDIVWLDVTRPLESNLARMAES
HHHHCCCEEEEEECCCHHHHHHHHHCCCHHHCCEECCCCCEEEEEECCCHHHHHHHHHHC
DHSRFPVCRGGLDDILGIISSKQLFNQTLKGGKADLTRHLETPVYVPESLTGMELLDQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ASSSRMVFVIDEYGEVQGMVTLQDVMEAVTGEFQPHRLEDAWAVQREDGSWLLDGLIPLP
CCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHEEECCCCEEECCCCCCH
ELKDRLELKSAPEEEKGRYHTLSGMIMWLLGRLPRTGDVTVWEQWRLEVVDLDGKRIDKI
HHHHHHHHCCCCCHHCCCEEHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCHHHHHH
LATRISNPEAGAPPQPATDTPEAP
HHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEVFILIALIILNGAFAMSEIALVTARRARLAKLAEEGDASAAVAIKLGEEPTRFLSTIQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHH
IGITSIGILNGIVGEAALAAPLAAWLQDLGLAQRPSEIGATVLVVMVITYISIVVGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVGQLNPEAIARLVAKPMNTLSIVSRPFVRLLSGSTAVLLRILGQRDESAPGVTEEEIH
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHH
ALLEEGSVAGIIEKNEHAMVRNVFRLDDRQIGSLMVPRSDIVWLDVTRPLESNLARMAES
HHHHCCCEEEEEECCCHHHHHHHHHCCCHHHCCEECCCCCEEEEEECCCHHHHHHHHHHC
DHSRFPVCRGGLDDILGIISSKQLFNQTLKGGKADLTRHLETPVYVPESLTGMELLDQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ASSSRMVFVIDEYGEVQGMVTLQDVMEAVTGEFQPHRLEDAWAVQREDGSWLLDGLIPLP
CCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHEEECCCCEEECCCCCCH
ELKDRLELKSAPEEEKGRYHTLSGMIMWLLGRLPRTGDVTVWEQWRLEVVDLDGKRIDKI
HHHHHHHHCCCCCHHCCCEEHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCHHHHHH
LATRISNPEAGAPPQPATDTPEAP
HHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]